Patents by Inventor Jennifer Stratton

Jennifer Stratton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody variants transmigrating the blood-brain barrier and uses thereof
    Patent number: 10906973
    Abstract: The present invention relates, in general, to polypeptides capable of transmigrating the blood-brain barrier, and uses thereof. More specifically, the present invention relates to polypeptides derived by site-directed mutagenesis of an existing antibody fragment and uses thereof, and methods of making such molecules. The polypeptides of the present invention show enhanced blood-brain barrier crossing and brain exposure levels in vitro and in vivo.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: February 2, 2021
    Assignees: National Research Council of Canada, Cephalon, Inc.
    Inventors: Danica Stanimirovic, Traian Sulea, Kristin Kemmerich, David Wilson, Jennifer Stratton, Matthew Pollard, Adam Clarke
  • ANTIBODY VARIANTS TRANSMIGRATING THE BLOOD-BRAIN BARRIER AND USES THEREOF
    Publication number: 20200095316
    Abstract: The present invention relates, in general, to polypeptides capable of transmigrating the blood-brain barrier, and uses thereof. More specifically, the present invention relates to polypeptides derived by site-directed mutagenesis of an existing antibody fragment and uses thereof, and methods of making such molecules. The polypeptides of the present invention show enhanced blood-brain barrier crossing and brain exposure levels in vitro and in vivo.
    Type: Application
    Filed: December 12, 2017
    Publication date: March 26, 2020
    Applicants: National Research Council of Canada, Cephalon, Inc.
    Inventors: Danica Stanimirovic, Traian Sulea, Kristin Kemmerich, David Wilson, Jennifer Stratton, Matthew Pollard, Adam Clarke
  • METHODS WANTED FOR TREATING UNWANTED WEIGHT LOSS OR EATING DISORDERS BY ADMINISTERING A TRKB AGONIST
    Publication number: 20070248611
    Abstract: This invention relates to methods for treating unwanted body weight loss (such as with cachexia and with aging), eating disorders (such as anorexia nervosa), or opioid-induced emesis by peripheral administration of a trkB agonist. The invention also relates to compositions and kits comprising a trkB agonist.
    Type: Application
    Filed: February 1, 2007
    Publication date: October 25, 2007
    Inventors: Chia-Yang Lin, Arnon Rosenthal, Jennifer Stratton
  • Methods of treating obesity or diabetes using NT-4/5
    Publication number: 20050209148
    Abstract: The invention concerns methods for treating obesity, non-insulin dependent diabetes mellitus, metabolic syndrome, and other related diseases by administering an NT-4/5 polypeptide. The invention also concerns compositions and kits comprising an NT-4/5 polypeptide.
    Type: Application
    Filed: February 22, 2005
    Publication date: September 22, 2005
    Inventors: Arnon Rosenthal, John Lin, Jennifer Stratton, Robert Klein, Jaume Pons