Abstract: A system can identify an attribute-based access control policy that comprises a pair comprising a permission policy and a condition policy that is associated with performing an operation on a computing resource. The system can identify that the attribute-based access control policy corresponds to a role policy that is associated with the account. The system can determine whether the account and the role policy satisfy the attribute-based access control policy with respect to the operation, wherein the determining comprises evaluating whether the computing resource and a required permission of the permission policy is declared in the role policy, and evaluating whether the account and the role policy satisfy the condition policy evaluates to true based on attributes of the account and attributes of the computing resource. The system can, in response to determining that the account satisfy the permission policy and the condition policy, perform the operation on the computing resource.

Abstract: The present disclosure relates to modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25, pharmaceutical compositions comprising the inhibitors, and methods of using the inhibitors. The modulators, such as inhibitors, of at least one pathway chosen from USP28 and USP25 can be useful in the treatment of cancers, among other ailments.

Abstract: Coated articles can comprise a coating disposed over a first major surface of a substrate. The coating comprises a plurality of functionalized oligomeric silsesquioxanes and a pencil hardness of about 5H or more. In aspects, the coating comprises a linker terminated with a first functional group and a second functional group. In aspects, the coating comprises a silane coupling agent attaching the coating to the first major surface. Methods of making a coated article comprise depositing a layer comprise a plurality of functionalized oligomeric silsesquioxanes over a first major surface of a substrate and curing the layer to form the coating. Methods of forming a composition comprise reacting a plurality of functionalized oligomeric silsesquioxanes with a linker terminated with a first functional group at a first end of the linker and a second functional group at a second end of the linker opposite the first end of the linker.

Abstract: A method for preparing a cooled radiofrequency probe for use to treat tissue of a patient's body includes providing a plurality of cooled radiofrequency probes. Each of the plurality of cooled radiofrequency probes includes an elongate member with a distal region and a proximal region. The distal regions each have an electrically and thermally-conductive energy delivery device for delivering one of electrical and radiofrequency energy to the patient's body. The electrically and thermally-conductive energy delivery devices each have one or more internal lumens for circulating a cooling fluid therethrough and an electrically and thermally-conductive protrusion having a temperature sensing element. The temperature sensing elements of each protrusion extends from a distal end of the energy delivery device. Further, each of the temperature sensing elements has a different length that extends from the distal end of the energy delivery device.

Abstract: This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a tetrahydroacridine (or similar) structure, an acridine (or similar) structure, a benzonaphthyridine (or similar) structure, or a tetrahydrobenzonaphthyridine (or similar) structure which function as autophagy inhibitors and/or histone deactylase inhibitors, and their use as therapeutics for the treatment of conditions characterized with aberrant autophagy activity and/or aberrant HDAC activity (e.g., cancer, pulmonary hypertension, diabetes, neurodegenerative disorders, aging, heart disease, rheumatoid arthritis, infectious discuses, conditions and symptoms caused by a viral infection (e.g., COVID-19)).

Abstract: Systems and methods for generating object references with selectable scopes are provided. The systems and methods perform operations including calling, by a first entity, a reference generator function using one or more arguments associated with a database object that the first entity is authorized to access according to a first set of access privileges, the one or more arguments comprising a scope definition that defines persistence of a reference. The operations include obtaining, from the reference generator function, a reference to the database object, the reference persisting according to the scope definition. The operations include passing the reference to a second entity to enable the second entity to perform one or more database operations on the database object according to a second set of access privileges derived from the first set of access privileges.

Abstract: A system receives vehicle metric data from a gateway device connected to a vehicle. The vehicle gateway device gathers data related to operation of the vehicle and/or location data. The system receives data from multiple vehicles. The vehicle gateway device gathers vehicle metric data and correlates the metric data with location data. The system presents the correlated data in an interactive map graphical user interface.

Abstract: An object induction system is disclosed for assigning handling parameters to an object. The system includes an analysis system, an association system, and an assignment system. The analysis system includes at least one characteristic perception system for providing perception data regarding an object to be processed. The association system includes an object information database and assigns association data to the object responsive to commonality with any of the characteristic perception data with any of the characteristic recorded data. The assignment system is for assigning programmable motion device handling parameters to the indicia perception data based on the association data, and includes a workflow management system as well as a separate operational controller.

Abstract: The present disclosure provides a method for conversion of a mixture of high-boiling fluorinated components comprising 1,1,3,3-tetrachloro-1-fluoropropane (HCFC-241fa), 1,3,3-trichloro-1,1-difluoropropane (HCFC-242fa), 1,1,3-trichloro-1,3-difluoropropane (HCFC-242fb), 3,3-dichloro-1,1,1-trifluoropropane (HCFC-243fa), 1,3-dichloro-1,1,3-trifluoropropane (HCFC-243fb), 3-chloro-1,1,1,3-tetrafluoropropane (HCFC-244fa), their isomers, and combinations thereof, to 1-chloro-3,3,3-trifluoropropene (HCFO-1233zd). Heavy impurities, such as oligomers and other high boiling impurities, that are present may be purged during the process to prevent yield loss and reduction of catalyst efficacy.

Abstract: A method and a system for using machine learning technology to optimize a scheduling strategy for establishing contact with a customer are provided. The method includes: receiving a data set that relates to a customer account; analyzing the data set to determine at least one proposed schedule for an attempt to contact the customer; and generating, based on a result of the analysis, a report that includes the proposed schedule. The analysis may be performed by applying a machine learning model that is trained by using historical data that relates to interactions associated with the customer.

Abstract: An analytics reporting system to perform operations that include: aggregating sensor data collected from a plurality of sensor devices within a database, the sensor data comprising a set of values that correspond with a metric; generating a threshold value based on the set of values that correspond with the metric; accessing a portion of the sensor data based on an identifier associated with the portion of the sensor data; determining the portion of the sensor data transgresses the threshold value; and generating a report that comprises a display of the portion of the sensor data based on the determining that the portion of the sensor data transgresses the threshold value.

Abstract: Aspects of the disclosure provide for controlling an autonomous vehicle. For instance, a trajectory for the autonomous vehicle to traverse in order to follow a route to a destination may be generated. A first error value for a boundary of an object, a second error value for a location of the autonomous vehicle, a third error value for a predicted future location of the object may be received. An uncertainty value for the object may be determined by combining the first error value, the second error value, and the third error value. A lateral gap threshold for the object may be determined based on the uncertainty value. The autonomous vehicle may be controlled in an autonomous driving mode based on the lateral gap threshold for the object.

Abstract: In some aspects, the described systems and methods provide for validating performance of a model trained on a plurality of annotated pathology images. In validating the trained model, frames may be sampled from one or more pathology images. Each frame may include a distinct portion of a pathology image. Reference annotations on the frames may be received from a plurality of users, each reference annotation describing at least one of a plurality of tissue or cellular characteristic categories or other biological objects for a frame. The frames may be processed using the trained model to generate model predictions, each model prediction describing at least one of the tissue or cellular characteristic categories for a processed frame. Performance of the trained model may be validated based on associating the model predicted annotations with the reference annotations across the one or more pathology images from the plurality of users.

Abstract: In-place recovery of fatal system errors at virtualization hosts. A device identifies an occurrence of a fatal system error in the first instance of a host operating system (OS) executing in a computer system. The device determines to perform an in-place recovery for the fatal system error. The device performs the in-place recovery, including pausing the execution of a virtual machine (VM) by the first instance of the host OS, preserving a state of the VM within system memory of the computer system, and resuming the execution of the VM by a second instance of the host OS executing in the computer system based on the state of the VM that is preserved within the system memory of the computer system.

Abstract: A method for real-time invoice updating and account-to-account payment includes: receiving invoice data based on presentation of an invoice by a distributor to a recipient at a delivery location, modification of the invoice by the recipient, and acceptance of the invoice by the recipient; generating a request for payment (RFP) message based on the invoice data; transmitting the RFP message to a financial institution associated with the recipient via a financial institution of the distributor; receiving, from the financial institution associated with the distributor, a payment confirmation for the invoice based on a real-time payment from the financial institution associated with the recipient; generating reconciliation data based on the payment confirmation and the invoice data; and transmitting the reconciliation data to a computing device of the distributor and a computing device of the recipient.

Abstract: A method for manufacturing electrodes for a battery cell includes providing a first free-standing electrode; providing a current collector including holes; providing a second free-standing electrode; and laminating the current collector between the first free-standing electrode and the second free-standing electrode using at least one of heat and pressure and without using a solvent.

Abstract: Disclosed are systems, methods, and non-transitory computer-readable storage media for managing projects using references between the project and project items. Project items can be, for example, synchronized content items, collaborative content items, other projects, folders, tasks, user accounts, etc. The content management system can create a project identifier for managing data and/or people associated with a project. In various implementations, the content management system can store references between the project and project items in one or more folders associated with the project, in a database, in content item metadata, etc. In some implementations, the storage location of a content item does not affect whether it is associated with the project. When a project is selected by a user, the content management system can generate project view that presents various project items associated with the project in a convenient and easy to access graphical user interface.