Abstract: A medical device may include a handle and a flexible sheath extending from the handle. The sheath may include a first chamber configured to receive a first agent and a second chamber configured to receive a second agent. Each of the first chamber and the second chamber may be disposed in a distal portion of the sheath. The sheath may also include a first piston received within the first chamber and a second piston received within the second chamber and at least one actuation element configured to transmit a force from the handle to each of the first piston and the second piston. In a first configuration, the first agent may be maintained within the first chamber and the second agent is maintained within the second chamber. In a second configuration, the first agent may be released from the first chamber to mix with the second agent.

Abstract: A medical system includes a propellant source containing a propellant fluid, containers containing a material, and a shaft having a plurality of lumens, each of the plurality of lumens having a first opening at a proximal end of the shaft and a second opening at a distal end of the shaft. The plurality of lumens are fluidly coupled to one or more of the propellant source and at least one of the plurality of containers, and a first lumen surrounds, is coaxial with, or is side-by-side with, at least one other lumen.

Abstract: A medical system includes a propellant source containing a propellant fluid, containers containing a material, and a shaft having a plurality of lumens, each of the plurality of lumens having a first opening at a proximal end of the shaft and a second opening at a distal end of the shaft. The plurality of lumens are fluidly coupled to one or more of the propellant source and at least one of the plurality of containers, and a first lumen surrounds, is coaxial with, or is side-by-side with, at least one other lumen.

Abstract: A delivery system for delivering a stent to a body lumen. The delivery system includes a tubular member having an expandable stent disposed about the outer surface of the inner tubular member. The stent is maintained in a radially compressed configuration with a removable sheath. The sheath can be released using a variety of techniques.

Abstract: In accordance with some aspects, the present disclosure is directed to medical compositions that comprises (a) a first hydrophilic polymer functionalized with a plurality of first functional groups and (b) a second hydrophilic polymer functionalized with a plurality of second functional groups, wherein the first and second functional groups are selected to react and form covalent bonds upon a change in conditions such that the first and second hydrophilic polymers crosslink with one another. In other aspects the present disclosure is directed to kits that comprise such medical compositions and to medical procedures that utilize such medical compositions.

Abstract: A delivery system for delivering a stent to a body lumen. The delivery system includes a tubular member having an expandable stent disposed about the outer surface of the inner tubular member. The stent is maintained in a radially compressed configuration with a removable sheath. The sheath can be released using a variety of techniques.

Abstract: In accordance with some aspects, the present disclosure is directed to medical compositions that comprises (a) a first hydrophilic polymer functionalized with a plurality of first functional groups and (b) a second hydrophilic polymer functionalized with a plurality of second functional groups, wherein the first and second functional groups are selected to react and form covalent bonds upon a change in conditions such that the first and second hydrophilic polymers crosslink with one another. In other aspects the present disclosure is directed to kits that comprise such medical compositions and to medical procedures that utilize such medical compositions.

Abstract: A valve assembly for a medical device that includes an enclosure for storing an agent and a funnel downstream of the enclosure for receiving the agent. The enclosure including a first end and the funnel including a second end positioned adjacent to the first end. The valve assembly including a first plate coupled to the enclosure at the first end, and a second plate coupled to the funnel at the second end. The first plate including at least one opening, and the second plate including at least one opening that is in fluid communication with the opening of the first plate. The first and second plates are positioned against one another, and an exterior surface of the first or second plate includes textured surface elements configured to displace the agent stored in the enclosure in response to the first or second plate moving relative to one another.

Abstract: A medical device may comprise a handle, a first shaft extending from a distal end of the handle, and a second shaft extending a lumen of the first shaft. The handle may further include a first actuator and a second actuator. The first shaft may include (1) a plurality of lumens extending therethrough, (2) a distal face, and (3) a longitudinal axis. Actuation of the first actuator may articulate a distal portion of the first shaft. The second shaft may be axially movable relative to the first shaft such that the second shaft extends out of a distal opening of the first lumen and distally of the distal face. Actuation of the second actuator may articulate a distal portion of the second shaft.

Abstract: A medical device comprising a first tube, a second tube configured to sheath at least a portion of the first tube and configured to translate along a length of the first tube, an expandable device at a distal portion of the first tube, the expandable device having a collapsed state and an expanded state, a patch surrounding at least a portion of an outer surface of the expandable device, and a connector for holding the patch to the expandable device when the second tube covers the patch and the expandable device and for releasing the patch from the expandable device after the second tube uncovers the patch and the expandable device.

Abstract: A delivery system for delivering a stent to a body lumen. The delivery system includes a tubular member having an expandable stent disposed about the outer surface of the inner tubular member. The stent is maintained in a radially compressed configuration with a removable sheath. The sheath can be released using a variety of techniques.

Abstract: A medical device may comprise a handle and a flexible sheath extending from the handle. The sheath may include a first chamber configured to receive a first agent and a second chamber configured to receive a second agent. Each of the first chamber and the second chamber may be disposed in a distal portion of the sheath. The sheath may also include a first piston received within the first chamber and a second piston received within the second chamber and at least one actuation element configured to transmit a force from the handle to each of the first piston and the second piston. When the handle is in a first configuration, the first agent may be maintained within the first chamber and the second agent is maintained within the second chamber. When the handle is in a second configuration, the first agent may be released from the first chamber to mix with the second agent.

Abstract: A medical system includes a propellant source containing a propellant fluid, containers containing a material, and a shaft having a plurality of lumens, each of the plurality of lumens having a first opening at a proximal end of the shaft and a second opening at a distal end of the shaft. The plurality of lumens are fluidly coupled to one or more of the propellant source and at least one of the plurality of containers, and a first lumen surrounds, is coaxial with, or is side-by-side with, at least one other lumen.

Abstract: In accordance with some aspects, the present disclosure is directed to medical compositions that comprises (a) a first hydrophilic polymer functionalized with a plurality of first functional groups and (b) a second hydrophilic polymer functionalized with a plurality of second functional groups, wherein the first and second functional groups are selected to react and form covalent bonds upon a change in conditions such that the first and second hydrophilic polymers crosslink with one another. In other aspects the present disclosure is directed to kits that comprise such medical compositions and to medical procedures that utilize such medical compositions.