Patents by Inventor Jennifer X. Qiao

Jennifer X. Qiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,1-Disubstitutedcycloalkyl-, glycinamidyl-, sulfonyl-amidino-, and tetrahydropyrimidinyl-containing diaminoalkyl, ?-aminoacids, ?-aminoacids and derivatives thereof as factor Xa inhibitors
    Patent number: 7250415
    Abstract: The present application describes 1,1-disubstitutedcycloalkyl-, glycinamidyl-, sulfonyl-amidino-, and tetrahydropyrimidinyl-containing diaminoalkyl, ?-aminoacids, ?-aminoacids and derivatives thereof of Formula I: P-M-M1I or a stereoisomer or pharmaceutically acceptable salt or solvate form thereof, wherein M is a linear core. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Grant
    Filed: June 1, 2004
    Date of Patent: July 31, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jennifer X. Qiao, Donald J. Pinto
  • Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors
    Patent number: 7205318
    Abstract: The present application describes lactam-containing cyclic diamines and derivatives thereof of Formula I: P4-M-M4I or pharmaceutically acceptable salt forms thereof, wherein M is a non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: April 17, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jennifer X. Qiao, Tammy C. Wang, Gren Z. Wang, Timur Gungor
  • Monocyclic and bicyclic lactams as factor Xa inhibitors
    Patent number: 7199149
    Abstract: The present application describes monocyclic and bicyclic lactams and derivatives thereof of Formulae Ia–e: wherein one of one of T1 and T2 is carbonyl, thiocarbonyl, or sulfonyl or pharmaceutically acceptable salt forms thereof. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Grant
    Filed: September 28, 2004
    Date of Patent: April 3, 2007
    Assignee: Bristol Myers Squibb Company
    Inventors: Wei Han, Jennifer X. Qiao, Zilun Hu
  • Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors
    Patent number: 7157470
    Abstract: The present application describes sulfonylaminovalerolactams and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein ring G is a mono- or bicyclic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Grant
    Filed: May 5, 2003
    Date of Patent: January 2, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joanne M. Smallheer, Donald J. Pinto, Shuaige Wang, Jennifer X. Qiao, Wei Han, Zilun Hu
  • Sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds as factor Xa inhibitors
    Patent number: 7122557
    Abstract: The present application describes sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds and derivatives thereof of Formula I: P4-P-M-M4I or pharmaceutically acceptable salt forms thereof, wherein M is a ring, P is an optional ring, and P4 and M4 are as defined below. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: October 17, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Donald J. Pinto, Jennifer X. Qiao, Timur Gungor, Patrick Y. S. Lam, Yun-Long Li
  • Cyclic diamines and derivatives as factor Xa inhibitors
    Patent number: 7115646
    Abstract: The present application describes cyclic diamino compounds, derivatives thereof, and pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa.
    Type: Grant
    Filed: October 6, 2004
    Date of Patent: October 3, 2006
    Assignee: Bristol Myers Squibb, Co.
    Inventor: Jennifer X. Qiao
  • Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
    Patent number: 6995172
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4-P-M-M4 I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5–7 membered carbocycle or heterocycle and ring M is a 5–7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: February 7, 2006
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Donald J. P. Pinto, Mimi L. Quan, Michael J. Orwat, Yun-Long Li, Wei Han, Jennifer X. Qiao, Patrick Y. S. Lam, Stephanie L. Koch
  • Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
    Patent number: 6989391
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4—P-M-M4??I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: January 24, 2006
    Assignee: Bristol-Myers-Squibb Pharma Company
    Inventors: Donald J. P. Pinto, Mimi L. Quan, Michael J. Orwat, Yun-Long Li, Jennifer X. Qiao, Patrick Y. S. Lam, Stephanie L. Koch
  • Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
    Patent number: 6967208
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Grant
    Filed: September 17, 2002
    Date of Patent: November 22, 2005
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Donald J. P. Pinto, Mimi L. Quan, Michael J. Orwat, Yun-Long Li, Wei Han, Jennifer X. Qiao, Patrick Y. S. Lam, Stephanie L. Koch
  • 1,1-Disubstitutedcycloalkyl-, glycinamidyl-, sulfonyl-amidino-, and Tetrahydropyrimidinyl-containing diaminoalkyl, beta-aminoacids, alpha-aminoacids and derivatives thereof as factor Xa inhibitors
    Publication number: 20040266761
    Abstract: The present application describes 1,1-disubstitutedcycloalkyl-, glycinamidyl-, sulfonyl-amidino-, and tetrahydropyrimidinyl-containing diaminoalkyl, &bgr;-aminoacids, &agr;-aminoacids and derivatives thereof of Formula I:
    Type: Application
    Filed: June 1, 2004
    Publication date: December 30, 2004
    Inventors: Jennifer X. Qiao, Donald J. Pinto
  • 1,1-Disubstituted cycloalkyl derivatives as factor Xa inhibitors
    Publication number: 20040254158
    Abstract: The present application describes 1,1-disubstituted cycloalkyl compounds and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa.
    Type: Application
    Filed: May 5, 2003
    Publication date: December 16, 2004
    Inventors: Jennifer X. Qiao, Donald J. Pinto, Michael J. Orwat, Sarah R. Friedrich, Wei Han
  • Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
    Publication number: 20040220174
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I:
    Type: Application
    Filed: May 20, 2004
    Publication date: November 4, 2004
    Inventors: Donald J.P. Pinto, Mimi L. Quan, Michael J. Orwat, Yun-Long Li, Wei Han, Jennifer X. Qiao, Patrick Y.S. Lam, Stephanie L. Koch
  • Sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds as factor Xa inhibitors
    Publication number: 20040209863
    Abstract: The present application describes sulfonyl-amidino-containing and tetrahydropyrimidino-containing compounds and derivatives thereof of Formula I:
    Type: Application
    Filed: March 16, 2004
    Publication date: October 21, 2004
    Inventors: Donald J. Pinto, Jennifer X. Qiao, Timur Gungor, Patrick Y.S. Lam, Yun-Long Li
  • Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors
    Publication number: 20040204454
    Abstract: The present application describes lactam-containing cyclic diamines and derivatives thereof of Formula I:
    Type: Application
    Filed: March 16, 2004
    Publication date: October 14, 2004
    Inventors: Jennifer X. Qiao, Tammy C. Wang
  • Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors
    Publication number: 20040132718
    Abstract: The present application describes monocyclic or bicyclic carbocycles and heterocycles and derivatives thereof of Formula I: 1
    Type: Application
    Filed: December 8, 2003
    Publication date: July 8, 2004
    Inventors: Irina C. Jacobson, Ruth R. Wexler, Suanne Nakajima, Mimi L. Quan, Shuaige Wang, Joanne M. Smallheer, Jennifer X. Qiao
  • Lactam-containing diaminoalkyl, beta-aminoacids, alpha-aminoacids and derivatives thereof as factor Xa inhibitors
    Publication number: 20040077635
    Abstract: The present application describes lactam-containing diaminoalkyl, &bgr;-aminoacids, &agr;-aminoacids and derivatives thereof of Formula I:
    Type: Application
    Filed: October 1, 2003
    Publication date: April 22, 2004
    Inventors: Jennifer X. Qiao, Wei Han
  • Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors
    Publication number: 20040006062
    Abstract: The present application describes sulfonylaminovalerolactams and derivatives thereof of Formula I: 1
    Type: Application
    Filed: May 5, 2003
    Publication date: January 8, 2004
    Inventors: Joanne M. Smallheer, Donald J. Pinto, Shuaige Wang, Jennifer X. Qiao, Wei Han, Zilun Hu
  • Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
    Publication number: 20030191115
    Abstract: The present application describes lactam-containing compounds and derivatives thereof of Formula I: 1
    Type: Application
    Filed: September 17, 2002
    Publication date: October 9, 2003
    Inventors: Donald J.P. Pinto, Mimi L. Quan, Michael J. Orwat, Yun-Long Li, Wei Han, Jennifer X. Qiao, Patrick Y.S. Lam, Stephanie L. Koch