Abstract: A continuous-flow system for the treatment of edema in an injured central nervous system (CNS) tissue, including: a reversibly implantable device having: an inflow pathway, an outflow pathway, and a fluid flow pathway connecting the first outlet of the inflow pathway and the second inlet of the outflow pathway, wherein the fluid flow pathway includes a semi-permeable membrane; a first reservoir; a fluid-driving apparatus; a second reservoir; and a plurality of fluid flow conduits that fluidically connect the first reservoir, the fluid-driving apparatus, the second reservoir, and the reversibly implantable device; wherein the reversibly implantable device is configured to allow direct contact between the semi-permeable membrane and at least a portion of the injured CNS tissue; wherein the system is configured to contain a solution that pass through the fluid flow pathway and induces osmotic flow of water from the injured CNS tissue across the semipermeable membrane and into the solution, thereby decreasing swe