Patents by Inventor Jennings Franklin Worley, III

Jennings Franklin Worley, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzoxazines as modulators of ion channels
    Patent number: 9365588
    Abstract: The invention relates to benzoxazines useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: June 14, 2016
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Sara Sabina Hadida-Ruah, Peter Diederik Jan Grootenhuis, Mark Thomas Miller, Corey Anderson, Joseph Pontillo, Edward Adam Kallel, Mehdi Michael Djamel Numa, Bryan A. Frieman, Jason McCartney, Jennings Franklin Worley, III, Vijayalaksmi Arumugam, Johnny Uy, Nicole Hilgraf, Brian Richard Bear
  • COMPOUNDS USEFUL IN CFTR ASSAYS AND METHODS THEREWITH
    Publication number: 20150293078
    Abstract: The present invention relates to compounds useful in CFTR assays. The present invention also relates to compounds useful in monitoring CFTR activity in therapies for CFTR-mediated diseases. The present invention also provides an assay for use in measuring CFTR correction.
    Type: Application
    Filed: April 17, 2015
    Publication date: October 15, 2015
    Inventors: Ashvani K. Singh, Fredrick F. Van Goor, Jennings Franklin Worley, III, Thomas Knapp
  • BENZOXAZINES AS MODULATORS OF ION CHANNELS
    Publication number: 20140309220
    Abstract: The invention relates to benzoxazines useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: November 2, 2012
    Publication date: October 16, 2014
    Inventors: Sara Sabina Hadida-Ruah, Peter Diederik Jan Grootenhuis, Mark Thomas Miller, Corey Anderson, Joseph Pontillo, Edward Adam Kallel, Mehdi Michael Djamel Numa, Bryan A. Frieman, Jason McCartney, Jennings Franklin Worley, III, Vijayalaksmi Arumugam, Johnny Uy, Nicole Hilgraf, Brian Richard Bear
  • COMPOUNDS USEFUL IN CFTR ASSAYS AND METHODS THEREWITH
    Publication number: 20090246820
    Abstract: The present invention relates to compounds useful in CFTR assays. The present invention also relates to compounds useful in monitoring CFTR activity in therapies for CFTR-mediated diseases. The present invention also provides an assay for use in measuring CFTR correction.
    Type: Application
    Filed: June 27, 2008
    Publication date: October 1, 2009
    Inventors: Ashvani K. Singh, Fredrick F. Van Goor, Jennings Franklin Worley, III, Thomas Knapp
  • Kv2.1 antagonists
    Patent number: 6589934
    Abstract: The invention relates to methods of treatment of non insulin dependent diabetes mellitus, antagonists of the delayed rectifier potassium channel Kv2.1, methods of using and preparing the antagonists and assays for identifying such antagonists.
    Type: Grant
    Filed: June 13, 2000
    Date of Patent: July 8, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Dulce Garrido Bubacz, Iain David Dukes, Ed Williams McLean, Robert Anderson Noe, Andrew James Peat, Jerzy Ryszard Szewczyk, Stephen Andrew Thomson, Jennings Franklin Worley, III