Patents by Inventor Jennitte STEVENS

Jennitte STEVENS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROMULTIMER BINDING DLL3 AND CD3
    Publication number: 20250282869
    Abstract: The disclosure provides a heteromultimer comprising a first heterodimer that binds to human delta-like ligand 3 (DLL3) and a second heterodimer that binds to human CD3, which can bind to DLL3-expressing cancer cells. The disclosure also provides methods of treating a DLL3-expressing cancer in a subject in need thereof, which comprises administering to the subject an effective amount of the heteromultimer or a composition comprising the heteromultimer.
    Type: Application
    Filed: May 4, 2023
    Publication date: September 11, 2025
    Applicants: AMGEN INC., AMGEN RESEARCH (MUNICH) GMBH
    Inventors: Julie BAILIS, Tobias RAUM, Matthias KLINGER, Doris RAU, Jennitte STEVENS, Suzanne EDAVETTAL, Reudiger NEEF, Janette WALTER, Mathias KAEFER, Tara ARVEDSON, Fernando GARCES
  • METHODS FOR REDUCING LOW MOLECULAR WEIGHT SPECIES OF RECOMBINANTLY-PRODUCED PROTEINS
    Publication number: 20240209115
    Abstract: The present invention relates to methods for reducing low molecular weight species of recombinantly-produced proteins. In particular, methods of reducing the formation of low molecular weight species produced by a host cell during the cell culture process through pH control of the production cell culture are disclosed. Also disclosed are methods for reducing or eliminating the generation of alternative splice variants by a host cell during production of a recombinant protein.
    Type: Application
    Filed: April 28, 2022
    Publication date: June 27, 2024
    Applicants: AMGEN INC., AMGEN RESEARCH (MUNICH) GmbH
    Inventors: Anika MENTHE, Joseph BASCONI, Nitya M. JACOB, Russell JAMPOL, Huong Thi Ngoc LE, Kim LE, Jessica PEDROSO, Jennitte STEVENS, Sreekanth SURAVAJJALA, Charilyn TEJAMO, Pheng YAM
  • Human antigen binding proteins that bind to a complex comprising ?-Klotho and an FGF receptor
    Patent number: 9574002
    Abstract: The present invention provides compositions and methods relating to or derived from antigen binding proteins capable of inducing B-Klotho, and or FGF21-like mediated signaling.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: February 21, 2017
    Assignee: AMGEN INC.
    Inventors: Yang Li, Jennitte Stevens, Chadwick Terence King, Ian Foltz, Gunasekaran Kannan, Junming Yie, Shaw-Fen Sylvia Hu
  • HUMAN ANTIGEN BINDING PROTEINS THAT BIND TO A COMPLEX COMPRISING BETA-KLOTHO AND AN FGF RECEPTOR
    Publication number: 20120328616
    Abstract: The present invention provides compositions and methods relating to or derived from antigen binding proteins capable of inducing B-Klotho, and or FGF21-like mediated signaling.
    Type: Application
    Filed: June 1, 2012
    Publication date: December 27, 2012
    Applicant: AMGEN INC.
    Inventors: YANG LI, Jennitte STEVENS, Chadwick Terence KING, Ian FOLTZ, Gunasekaran KANNAN, Junming YIE, Shaw-Fen Sylvia HU