Patents by Inventor Jenny B. Lin

Jenny B. Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR
    Publication number: 20230346960
    Abstract: The present disclosure provides pro-angiogenic proteoglycan mimetics that can provide a provisional, pro-angiogenic scaffold to support tissue regeneration while limiting systemic exposure to VEGF activity. These mimetics can protect a collagen matrix from rapid degradation, and in conjunction with EPCs promote angiogenesis in order to accelerate ischemic wound healing. For example, the provided compounds can be delivered from the end of a catheter following balloon angioplasty to coat the collagen exposed areas, prevent platelet binding and thrombosis, support capture of EPCs from blood to facilitate reendothelialization, and reduce late-lumen loss (neointimal hyperplasia).
    Type: Application
    Filed: February 14, 2023
    Publication date: November 2, 2023
    Applicants: The Regents of the University of California, Purdue Research Foundation
    Inventors: Alyssa Panitch, Emily Michelle Misnick, Jenny B. Lin, Kit S. Lam, Ruiwu Liu, Dake Hao, Aijun Wang
  • Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair
    Patent number: 11612663
    Abstract: The present disclosure provides pro-angiogenic proteoglycan mimetics that can provide a provisional, pro-angiogenic scaffold to support tissue regeneration while limiting systemic exposure to VEGF activity. These mimetics can protect a collagen matrix from rapid degradation, and in conjunction with EPCs promote angiogenesis in order to accelerate ischemic wound healing. For example, the provided compounds can be delivered from the end of a catheter following balloon angioplasty to coat the collagen exposed areas, prevent platelet binding and thrombosis, support capture of EPCs from blood to facilitate reendothelialization, and reduce late-lumen loss (neointimal hyperplasia).
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: March 28, 2023
    Assignees: The Regents of the University of California, Purdue Research Foundation
    Inventors: Alyssa Panitch, Emily Michelle Misnick, Jenny B. Lin, Kit S. Lam, Ruiwu Liu, Dake Hao, Aijun Wang
  • PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR
    Publication number: 20210093728
    Abstract: The present disclosure provides pro-angiogenic proteoglycan mimetics that can provide a provisional, pro-angiogenic scaffold to support tissue regeneration while limiting systemic exposure to VEGF activity. These mimetics can protect a collagen matrix from rapid degradation, and in conjunction with EPCs promote angiogenesis in order to accelerate ischemic wound healing. For example, the provided compounds can be delivered from the end of a catheter following balloon angioplasty to coat the collagen exposed areas, prevent platelet binding and thrombosis, support capture of EPCs from blood to facilitate reendothelialization, and reduce late-lumen loss (neointimal hyperplasia).
    Type: Application
    Filed: October 2, 2020
    Publication date: April 1, 2021
    Applicants: The Regents of the University of California, Purdue Research Foundation
    Inventors: Alyssa Panitch, Emily Michelle Misnick, Jenny B. Lin, Kit S. Lam, Ruiwu Liu, Dake Hao, Aijun Wang