Patents by Inventor Jenny Che

Jenny Che has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING CANCER WITH IMMUNE CELLS
    Publication number: 20250049846
    Abstract: The invention provides compositions and methods for treating a patient with cancer with an immune cell, e.g., a T-cell, e.g., an engineered T-cell, with increased sialidase activity. The invention also provides compositions and methods for treating a patient with cancer with an immune cell, e.g., a T-cell, e.g., an engineered T-cell, in combination with a sialidase. The invention also provides compositions and methods for treating a patient with cancer with an immune cell, e.g., a T-cell, e.g., an engineered T-cell, pretreated with a sialidase.
    Type: Application
    Filed: January 3, 2020
    Publication date: February 13, 2025
    Inventors: Ahmed Alkhateeb, Karl D. Normington, Li Peng, James W. Broderick, Zakir B. Siddiquee, Jenny Che, Weiguo Yao, Abhishek Das
  • ANTI-PD-L1 ANTIBODIES AND FUSION PROTEINS THEREOF
    Publication number: 20240067729
    Abstract: The invention relates generally to anti-PD-L1 antibodies, and recombinant sialidase and anti-PD-L1 immunoglobulin antigen-binding domain fusion proteins. The invention also provides antibody conjugates including a sialidase and an anti-PD-L1 antibody or a portion thereof. The invention further relates to methods of using the antibodies, sialidase fusion proteins, or antibody conjugates for treating cancer.
    Type: Application
    Filed: January 6, 2022
    Publication date: February 29, 2024
    Inventors: Li Peng, Jenny Che, Lihui Xu
  • SIALIDASE-HER2-ANTIBODY FUSION PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20220387616
    Abstract: The invention relates generally to recombinant sialidase and anti-HER2 immunoglobulin antigen-binding domain fusion proteins. The invention also provides antibody conjugates including a sialidase and an anti-HER2 antibody or a portion thereof. The invention further relates to methods of using the sialidase fusion proteins or antibody conjugates for treating cancer.
    Type: Application
    Filed: July 3, 2020
    Publication date: December 8, 2022
    Inventors: Li Peng, Lizhi Cao, Wayne C. Gatlin, Weiguo Yao, Zakir B. Siddiquee, Sujata B. Nerle, Jenny Che