Patents by Inventor Jenny Ellen Rooke

Jenny Ellen Rooke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8697399
    Abstract: The present invention provides methods of determining the size of a particular nucleic acid segment of interest in a sample of nucleic acids through fragmentation of DNA, size fractionation, an optional second fragmentation, and identification using a marker sequence. In particular aspects, an expansion or reduction of tandem repeat sequences can be detected. In further aspects, carriers and individuals afflicted with fragile X syndrome or other diseases associated with tandem repeats can be distinguished from normal individuals.
    Type: Grant
    Filed: April 11, 2007
    Date of Patent: April 15, 2014
    Assignees: Quest Diagnostics Investments Incorporated, US Genomics, Inc.
    Inventors: Donghui Huang, Charles M. Strom, Steven J. Potts, Jenny Ellen Rooke
  • Patent number: 8163480
    Abstract: The present invention provides methods of determining the size of a particular nucleic acid segment of interest in a sample of nucleic acids through fragmentation of DNA, size fractionation, an optional second fragmentation, and identification using a marker sequence. In particular aspects, an expansion or reduction of tandem repeat sequences can be detected. In further aspects, carriers and individuals afflicted with fragile X syndrome or other diseases associated with tandem repeats can be distinguished from normal individuals.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: April 24, 2012
    Assignees: Quest Diagnostics Investments Incorporated, US Genomics, Inc.
    Inventors: Donghui Huang, Charles M. Strom, Steven J. Potts, Jenny Ellen Rooke
  • Publication number: 20100167284
    Abstract: The present invention provides methods of determining the size of a particular nucleic acid segment of interest in a sample of nucleic acids through fragmentation of DNA, size fractionation, an optional second fragmentation, and identification using a marker sequence. In particular aspects, an expansion or reduction of tandem repeat sequences can be detected. In further aspects, carriers and individuals afflicted with fragile X syndrome or other diseases associated with tandem repeats can be distinguished from normal individuals.
    Type: Application
    Filed: April 11, 2007
    Publication date: July 1, 2010
    Inventors: Donghui Huang, Charles M. Strom, Steven J. Potts, Jenny Ellen Rooke
  • Publication number: 20080124709
    Abstract: The present invention provides methods of determining the size of a particular nucleic acid segment of interest in a sample of nucleic acids through fragmentation of DNA, size fractionation, an optional second fragmentation, and identification using a marker sequence. In particular aspects, an expansion or reduction of tandem repeat sequences can be detected. In further aspects, carriers and individuals afflicted with fragile X syndrome or other diseases associated with tandem repeats can be distinguished from normal individuals.
    Type: Application
    Filed: October 5, 2006
    Publication date: May 29, 2008
    Inventors: Donghui Huang, Charles M. Strom, Steven J. Potts, Jenny Ellen Rooke