Patents by Inventor Jenny Karlsson

Jenny Karlsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220125960
    Abstract: The present invention relates to combinations of at least two components, component A and component B, component A being a PD-1/PD-L1 inhibitor, and component B being a targeted thorium conjugate. Another aspect of the present invention relates to the use of such combinations as described herein for the preparation of a medicament for the treatment or prophylaxis of a disease, particularly for the treatment of breast and prostate cancer.
    Type: Application
    Filed: February 17, 2020
    Publication date: April 28, 2022
    Applicants: Bayer Aktiengesellschaft, Bayer AS
    Inventors: Urs Beat HAGEMANN, Pascale LEJEUNE, Jenny KARLSSON, Alan CUTHBERTSON, Stefanie HAMMER
  • Publication number: 20220118123
    Abstract: The present invention covers combinations of at least two components, component A and component B, comprising component A being PSMA-TTC, and component B being an antiandrogen selected form AR antagonists such as from cyproterone acetate, bicalutamide, flutamide, nilutamide, enzalutamide, apalutamide, darolutamide or keto-darolutamide, or an AR degrader such as ARV-110, or an ARN-terminal domain binder such as EPI-506, or an antisense oligonucleotide that reduces AR expression such as EZN-4176 or AZD-5312, or an androgen synthesis inhibitor such as abiraterone, particularly abiraterone acetate, seviteronel, galeterone, orteronel or ketoconazole, or a dual AR antagonist and androgen synthesis inhibitor such as ODM-204. Another aspect of the present invention covers the use of such combinations as described herein for the preparation of a medicament for the treatment or prophylaxis of a disease, particularly for the treatment of a hyper-proliferative disease.
    Type: Application
    Filed: February 17, 2020
    Publication date: April 21, 2022
    Applicants: Bayer Aktiengesellschaft, BAYER AS
    Inventors: Stefanie HAMMER, Urs Beat HAGEMANN, Bernard HAENDLER, Pascale LEJEUNE, Sabine ZITZMANN-KOLBE, Christoph SCHATZ, Jenny KARLSSON
  • Publication number: 20190298865
    Abstract: The invention provides a method for the formation of a tissue-targeting thorium complex, said method comprising; a) forming an octadentate chelator comprising four hydroxypyridinone (HOPO) moieties, substituted in the N-position with a methyl group, and a coupling moiety terminating in a carboxylic acid group; b) coupling said octadentate chelator to at least one tissue-targeting moiety targeting prolyl endopeptidase FAP; and c) contacting said tissue-targeting chelator with an aqueous solution comprising an ion of at least one alpha-emitting thorium isotope. A method of treatment of a neoplastic or hyperplastic disease comprising administration of such a tissue-targeting thorium complex, as well as the complex and corresponding pharmaceutical formulations are also provided.
    Type: Application
    Filed: June 6, 2017
    Publication date: October 3, 2019
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER AS
    Inventors: Alan CUTHBERTSON, Mark TRAUTWEIN, Ernst WEBER, Jenny KARLSSON, Stefanie HAMMER
  • Publication number: 20160214177
    Abstract: The invention relates to a corrosion and wear resistance cold work tool steel. The steel includes the following main components (in wt. %): C 0.3-0.8, N 1.0-2.2, (C+N) 1.3-2.2, C/N 0.17-0.50, Si?1.0, Mn 0.2-2.0, Cr 13-30, Mo 0.5-3.0, V 2.0-5.0, balance optional elementals, iron and impurities.
    Type: Application
    Filed: October 2, 2014
    Publication date: July 28, 2016
    Inventors: Sebastian Ejnermark, Thomas Hillskog, Lars Ekman, Rikard Robertsson, Victoria Bergqvist, Jenny Karlsson, Petter Damm, Ulrika Mossfeldt, Roland Edvinsson, Annika Engstrom Svensson, Berne Hogman