Abstract: The present invention is directed to antibodies and antigen binding fragments thereof having binding specificity for PACAP. The antibodies and antigen binding fragments thereof comprise the sequences of the VH, VL, and CDR polypeptides described herein, and the polynucleotides encoding them. Antibodies and antigen binding fragments described herein bind to and/or compete for binding to the same linear or conformational epitope(s) on human PACAP as an anti-PACAP antibody. The invention contemplates conjugates of anti-PACAP antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. Methods of making said anti-PACAP antibodies and antigen binding fragments thereof are also contemplated.

Abstract: A method for treating coronavirus infection and bacterial infection in a subject in need thereof, including: applying to the subject a topical solution containing a therapeutically effective amount of Phyllanthus urinaria (PU) extract or one of its physiologically acceptable forms; and administering to the subject a composition comprising a therapeutically effective amount of Houttuynia cordata (HC) extract or one of its physiologically acceptable forms.

Abstract: A multi time-phase treatment for one of a range of maladies. A dosage form is administered in a first dosage of a therapeutic effective amount of a first plant concentrate or one of its physiological acceptable forms. A dosage form is administered in a second dosage of a therapeutic effective amount of a second plant concentrate or one of its physiological acceptable forms. The first dosage is applied at a first time-phase and the second dosage is applied at a second time-phase spaced from the first time-phase. A combination of the first and second dosage forms administered in at least the first and second time-phases assist in treatment of abnormal cells for treatment for one of the range of maladies.

Abstract: Disclosed herein is a sensor attached to viscera to measure a change in length, in which the sensor includes a first layer having a first surface attached to the viscera and a second surface opposite to the first surface, a second layer having a third surface attached to the second surface and a fourth surface opposite to the third surface and expanded or contracted as the viscera is expanded or contracted, and a third layer having a fifth surface attached to the fourth surface and a sixth surface opposite to the fifth surface and attached to a catheter, and the first layer to the third layer are a film including silk fibroin and a calcium compound.

Abstract: A multi time-phase treatment for one of a range of maladies. A dosage form is administered in a first dosage of a therapeutic effective amount of a first plant concentrate or one of its physiological acceptable forms. A dosage form is administered in a second dosage of a therapeutic effective amount of a second plant concentrate or one of its physiological acceptable forms. The first dosage is applied at a first time-phase and the second dosage is applied at a second time-phase spaced from the first time-phase. A combination of the first and second dosage forms administered in at least the first and second time-phases assist in treatment of abnormal cells for treatment for one of the range of maladies.

Abstract: Disclosed herein is a sensor attached to viscera to measure a change in length, in which the sensor includes a first layer having a first surface attached to the viscera and a second surface opposite to the first surface, a second layer having a third surface attached to the second surface and a fourth surface opposite to the third surface and expanded or contracted as the viscera is expanded or contracted, and a third layer having a fifth surface attached to the fourth surface and a sixth surface opposite to the fifth surface and attached to a catheter, and the first layer to the third layer are a film including silk fibroin and a calcium compound.

Abstract: A neural probe structure has a probe having a microfluidic channel. The probe is inserted into an inside of a subject. A body to which the probe is fixed has a fluid entrance communicating with the microfluidic channel. A cover element is fixed to the body to cover the fluid entrance. The cover element has a connecting opening to which an external conduit is connected, and a fluid delivery channel extending such that the connecting opening and the fluid entrance are in fluid communication. A fluid fed from the external conduit flows along the fluid delivery channel, goes into the fluid entrance, and is delivered to the subject through the microfluidic channel.

Abstract: The present disclosure is directed to organic electroluminescent devices comprising thermally activated emission material(s) in an emission layer. The present disclosure is also directed to compounds capable of providing thermally activated delayed fluorescence, and to emission layers comprising at least one of the compounds. The compounds may be used in organic layers such as emission layers of an organic electroluminescence device such as fluorescent OLEDs.

Abstract: Breast-supportive garments comprise a left cup structure, a right cup structure, a first supportive panel, and a second supportive panel. The right cup structure is operatively coupled to the left cup structure. The first supportive panel extends from left of the left cup structure to right of the right cup structure, extending at least partially below the left cup structure and at least partially below the right cup structure. The second supportive panel extends from right of the right cup structure to left of the left cup structure, extending at least partially below the right cup structure and at least partially below the left cup structure. One of the first supportive panel and the second supportive panel extends substantially in front of the other of the first supportive panel and the second supportive panel.

Abstract: A neural probe structure has a probe having a microfluidic channel. The probe is inserted into an inside of a subject. A body to which the probe is fixed has a fluid entrance communicating with the microfluidic channel. A cover element is fixed to the body to cover the fluid entrance. The cover element has a connecting opening to which an external conduit is connected, and a fluid delivery channel extending such that the connecting opening and the fluid entrance are in fluid communication. A fluid fed from the external conduit flows along the fluid delivery channel, goes into the fluid entrance, and is delivered to the subject through the microfluidic channel.

Abstract: The invention concerns a process for the production of a low-fat mozzarella comprising the steps of preparing a bulking pre-mix of dry components such as one or a mixture of rennet casein, sodium casein, milk protein concentrate and whey protein concentrate, salt, potassium sorbate and/or sorbic acid, sodium aluminium phosphate, sodium citrate, starch, skim milk powder, and stabiliser; adding said pre-mix to water at ambient temperature; raising the temperature to 80 to 85° C. whilst stirring the mixture; and adding natural mozzarella, sequestering agent, and citric acid monohydrate or lactic acid until the mixture is smooth and homogeneous.

Abstract: A micro sensing system for real-time sensing a neurotrophic factor included in a body fluid includes a body, a neurotrophic factor channel formed in the body to allow a fluid flow therein, and a biosensor formed at the body to sense the neurotrophic factor, wherein the body fluid is extracted in a living body through the neurotrophic factor channel, and wherein the biosensor is disposed on a path of the neurotrophic factor channel to directly contact a body fluid flowing through the neurotrophic factor channel and senses a concentration of a neurotrophic factor in the body fluid.

Abstract: A neural probe array includes a probe body that is implanted into a subject, a fixture body to support a rear end of the probe body, a cladding extending in a lengthwise direction of the probe body in an upper part of the probe body, and an optical waveguide member installed on the cladding along the cladding, and the cladding is embedded in a recessed cavity formed in the upper part of the probe body. A method for manufacturing the neural probe array includes forming the cavity in an upper part of a first substrate, embedding the cladding in the cavity, forming the optical waveguide member on the cladding along the cladding, and forming the probe body by cutting the first substrate off.

Abstract: As an apparatus for manufacturing a micro lens array includes a first substrate having a plurality of cavities formed at locations corresponding to locations of the plurality of micro lenses, and a second substrate having a lower softening point than the first substrate and bonded on the first substrate to close the plurality of cavities, wherein a portion of the second substrate located on the cavities swells convexly by air trapped in the cavities expanding its volume in response to a temperature above the softening point of the second substrate being applied, to form domes corresponding to a shape of the micro lenses, and the micro lens array is cast using the second substrate having the formed domes as a mold.

Abstract: A bag for the transportation of table settings. The bag may have multiple compartments with multiple sections within the compartments. The sections may be configured to fit table setting items to prevent damage during transportation.

Abstract: An organic electroluminescent device comprising: a pair of electrodes comprising an anode and a cathode, and one or more layers arranged between the anode and the cathode; wherein at least one of the one or more layers is a light emitting layer and wherein the one or more layers, comprises an organic compound represented by a substituted 2,2?-biimidazole.

Abstract: A thin, flat device (10) for inserting scrapbook page device (22) for quick application of article protectors (20). The device is made of a flexible material, with a spine (12) so it can be repeatedly folded, without fracturing, tearing or cracking. In addition it provides a fast, easy and hassles free approach to applying article protectors (20). Not only does it provide a quick method of inserting it also protects a scrapbook page (22) from being torn, folded, bent or torn during the application of article protectors (20).

Abstract: An assembly of denture bridge includes a lingual restoration and a buccal restoration so as to install a denture to the place where a tooth is missing. The buccal restoration has two wings on two ends thereof so as to contact the inside of the nature teeth and the lingual restoration is formed according the mesio-distal side of the lingual side and the occusal surface. Two lingual restorations are connected to the buccal restoration by a screw so as to secured onto the nature teeth. The nature teeth need not to be remove a lot and the denture can be set within a short period of time. The patient needs not to wear a temporary grown.

Abstract: A nonwoven structure or web is provided where a binder fiber contains an energy receptive additive. The fiber provides rapid heating when subjected to dielectric energy such as radio frequency or microwave radiation. The energy receptive additive has a dielectric loss of at between 0.5, preferably 0.1 and most preferably 5, and 15.