Patents by Inventor Jenny Presto

Jenny Presto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE
    Publication number: 20180305404
    Abstract: The present invention relates to the field of molecular biochemistry and medicine, and in particular to ligands comprising modified amino acid residues, targeting the amyloid-? peptide associated with Alzheimer's disease for prevention of aggregation, neurotoxicity and use thereof as drugs for treatment of Alzheimer's disease.
    Type: Application
    Filed: May 15, 2018
    Publication date: October 25, 2018
    Inventors: Roger Strömberg, Dmytro Honcharenko, Jyotirmoy Maity, Alok Juneja, Firoz Roshan Kurudenkandy, Jenny Presto, Lisa Dolfe, André Fisahn, Jan Johansson, Lennart Nilsson
  • Ligands for prevention of neurotoxicity of the alzheimer's disease related amyloid-beta peptide
    Patent number: 10023610
    Abstract: The present invention relates to the field of molecular biochemistry and medicine, and in particular to ligands comprising modified amino acid residues, targeting the amyloid-? peptide associated with Alzheimer's disease for prevention of aggregation, neurotoxicity and use thereof as drugs for treatment of Alzheimer's disease.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: July 17, 2018
    Assignee: AlphaBeta AB
    Inventors: Roger Strömberg, Dmytro Honcharenko, Jyotirmoy Maity, Alok Juneja, Firoz Roshan Kurudenkandy, Jenny Presto, Lisa Dolfe, André Fisahn, Jan Johansson, Lennart Nilsson
  • Methods of screening compounds for the fibril formation of A? peptides based on a decreased trimer/monomer ratio of a chaperone protein
    Patent number: 9522170
    Abstract: A method involves screening a candidate compound for activity in the treatment of a condition associated with formation of amyloid protein fibrils in a mammal, such as Alzheimer's disease. It is determined whether the trimer/monomer ratio of a chaperone protein is decreased in the presence of the candidate compound. The chaperone protein is or has a high identity to the Brichos domains of Bri2, Bri3 or proSP-C from human. Monomers of the chaperone proteins and/or compounds that promote formation of these monomers are useful for medical treatment of the condition.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: December 20, 2016
    Assignee: ALPHABETA AB
    Inventors: Jan Johansson, Jenny Presto
  • NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE
    Publication number: 20160340387
    Abstract: The present invention relates to the field of molecular biochemistry and medicine, and in particular to ligands comprising modified amino acid residues, targeting the amyloid-? peptide associated with Alzheimer's disease for prevention of aggregation, neurotoxicity and use thereof as drugs for treatment of Alzheimer's disease.
    Type: Application
    Filed: January 16, 2015
    Publication date: November 24, 2016
    Inventors: Roger Strömberg, Dmytro Honcharenko, Jyotirmoy Maity, Alok Juneja, Firoz Roshan Kurudenkandy, Jenny Presto, Lisa Dolfe, André Fisahn, Jan Johansson, Lennart Nilsson
  • AMYLOIDOSIS TARGET USEFUL IN METHODS OF TREATMENT AND FOR SCREENING OF COMPOUNDS
    Publication number: 20140030274
    Abstract: A method involves screening a candidate compound for activity in the treatment of a condition associated with formation of amyloid protein fibrils in a mammal, such as Alzheimer's disease. It is determined whether the trimer/monomer ratio of a chaperone protein is decreased in the presence of the candidate compound. The chaperone protein is or has a high identity to the Brichos domains of Bri2, Bri3 or proSP-C from human. Monomers of the chaperone proteins and/or compounds that promote formation of these monomers are useful for medical treatment of the condition.
    Type: Application
    Filed: March 30, 2012
    Publication date: January 30, 2014
    Applicant: AlphaBeta AB
    Inventors: Jan Johansson, Jenny Presto