Abstract: Methods and systems to predict network performance of a network are disclosed. In one embodiment, a method comprises: training a first sub-model using a subset of a plurality of time series of data values, where the first sub-model comprises a type of generalized additive model, and where training the first sub-model comprises determining parameters within a plurality of univariate functions of the first sub-model; and training a second sub-model using the subset of the time series of data values, wherein the second sub-model comprises a type of autoregressive integrated moving average (ARIMA) model. The method further comprises determining a weight distribution between the first and second sub-models using additional data values from the time series of data values to generate a hybrid model incorporating the first and second sub-models, and predicting a data value of the performance indicator of the network at a later day using the hybrid model.

Abstract: Anti-angiogenic agents or polypeptides have an amino acid segment substantially similar to domain one of CD2. The polypeptide has a ?-sheet formed by two segments. Methods of using such agents and polypeptide are also included.

Abstract: A method of synchronizing tasks in a test and measurement system, includes receiving, at a client in the system, a task input, receiving, at a job manager running on a first device processor in the system, a call from the client to create a job associated with the task, returning to the client an action containing at least one job code block associated with the job, receiving a call for the action, executing the at least one job code block by at least one processor in the system, determining that the job has completed, and completing the task.

Abstract: Anti-angiogenic agents or polypeptides have an amino acid segment substantially similar to domain one of CD2. The polypeptide has a ?-sheet formed by two segments. Methods of using such agents and polypeptide are also included.

Abstract: A method of synchronizing tasks in a test and measurement system, includes receiving, at a client in the system, a task input, receiving, at a job manager running on a first device processor in the system, a call from the client to create a job associated with the task, returning to the client an action containing at least one job code block associated with the job, receiving a call for the action, executing the at least one job code block by at least one processor in the system, determining that the job has completed, and completing the task.

Abstract: A non-toxic anti-angiogenesis protein that inhibits tumor growth and exhibits in vitro activity in induction of angiogenic endothelial cell apoptosis without targeting VEGF/VEGFR or any other RTK pathways is described. The protein targets integrins ?v?3, at a groove in the ?A domain of ?3 formed by ?2 helix, B-C loop, and ?2-?3 loop.

Abstract: Anti-angiogenic agents or polypeptides comprising an amino acid segment substantially similar to domain one of CD2 wherein the polypeptide has a ?-sheet formed by two segments. Methods of using such agents and polypeptide are also included.

Abstract: A method for constructing an analyte binding motif by accessing a database that comprises structural data on analyte binding sites, generating at least one preliminary analyte binding site from the structural data, selecting an analyte binding site from the at least one preliminary analyte binding sites, and constructing the analyte binding motif by tailoring the selected analyte binding site and operatively linking it with a host protein, in which the analyte binding motif has a specificity for a selected analyte.

Abstract: A method for constructing an analyte binding motif by identifying an analyte binding peptide that binds an analyte with specificity, ascertaining at least a portion of a nucleic acid sequence encoding the analyte binding peptide, tailoring the nucleic acid sequence encoding the analyte binding peptide into an analyte binding site, identifying a host protein and a relevant portion of the nucleic acid sequence of the host protein, operatively linking the tailored nucleic acid sequence encoding the analyte binding peptide and the host protein nucleic acid sequence into an analyte binding motif sequence, and expressing analyte binding motif sequence, in which the nucleic acid sequence encoding the analyte binding peptide is tailored so as to achieve the analyte binding motif with a desired specificity for the analyte. Also, the proteins encoded by the analyte binding motif sequence as constructed by the method.

Abstract: An analyte sensor with a tailored analyte binding motif that binds an analyte and a host protein operatively linked to the analyte binding motif, in which the binding of the analyte to the analyte binding motif produces a detectable change and manipulation of the analyte binding motif manipulates the responsiveness of the sensor. Also, a method for constructing an analyte sensor by constructing a tailored analyte binding motif capable of responding to an analyte and operatively inserting the analyte binding motif into a host protein. Included is a method for quantifying an analyte by introducing a nucleotide sequence for a protein having an analyte sensor with a tailored analyte binding motif that is able to produce a detectable change upon excitation, expressing the protein, providing excitement to the analyte sensor, and quantifying the detectable change.