Patents by Inventor Jens Brodbeck

Jens Brodbeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of identifying agents that modulate mitochondrial function
    Patent number: 8512958
    Abstract: The present invention provides isolated cells comprising a nucleic acid encoding a toxic form of apoE. The present invention further provides screening methods for identifying compounds that reduce apoE-induced impairment of mitochondrial integrity and/or function. The present invention further provides kits for use in carrying out a subject screening method. The present invention provides agents that reduce apoE-induced impairment of mitochondrial integrity and/or function; and use of such agents in the treatment of apoE-related disorders.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: August 20, 2013
    Assignee: The J. David Gladstone Institutes
    Inventors: Yadong Huang, Jens Brodbeck
  • Methods of identifying agents that modulate mitochondrial function
    Publication number: 20070178535
    Abstract: The present invention provides isolated cells comprising a nucleic acid encoding a toxic form of apoE. The present invention further provides screening methods for identifying compounds that reduce apoE-induced impairment of mitochondrial integrity and/or function. The present invention further provides kits for use in carrying out a subject screening method. The present invention provides agents that reduce apoE-induced impairment of mitochondrial integrity and/or function; and use of such agents in the treatment of apoE-related disorders.
    Type: Application
    Filed: December 7, 2006
    Publication date: August 2, 2007
    Inventors: Yadong Huang, Jens Brodbeck