Patents by Inventor Jens Broscheit

Jens Broscheit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210137919
    Abstract: The invention provides a pharmaceutical buccal, sublingual, gingival or intranasal formulation comprising tadalafil or salt thereof as active substance, a polymer, and a surfactant, and also a method for the production thereof and the use of the formulation in a medicament for treating sexual dysfunction. The average particle size of the active substance is within a range from 8 to 500 nm and the polymer is polyvinylpyrrolidone (PVP) and/or vinylpyrrolidone-vinyl acetate copolymer (KVA). The surfactant may, for example, be sodium dodecyl sulfate (SDS). The maximum serum active substance concentration occurs within just 1 hour after administration of the medicament.
    Type: Application
    Filed: February 7, 2019
    Publication date: May 13, 2021
    Inventors: Norbert Roewer, Jens Broscheit, Isabell Steer
  • Publication number: 20210047441
    Abstract: The invention relates to a complex of pure anthocyanidin and a sulfoalkyl ether ?-cyclodextrin, which complex can be formulated as an aqueous solution and as a solid, and a method for producing such a complex. Complexes according to the invention are storage-stable and can be well formulated as an aqueous solution.
    Type: Application
    Filed: April 28, 2020
    Publication date: February 18, 2021
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20210030713
    Abstract: The invention relates to a complex of an anthocyanidin and a methylated ?-cyclodextrin which can be formulated as an aqueous solution and as a solid, and to a process for the preparation of such a complex. Complexes according to the invention are storage-stable and can be readily formulated in aqueous solution.
    Type: Application
    Filed: May 18, 2020
    Publication date: February 4, 2021
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20180298115
    Abstract: The invention relates to a complex of pure anthocyanidin and a sulfoalkyl ether ?-cyclodextrin, which complex can be formulated as an aqueous solution and as a solid, and a method for producing such a complex. Complexes according to the invention are storage-stable and can be well formulated as an aqueous solution.
    Type: Application
    Filed: June 20, 2018
    Publication date: October 18, 2018
    Inventors: Norbert Roewer, Jens Broscheit
  • Patent number: 10085949
    Abstract: A method for producing a flurane complex, comprising the steps of producing an aqueous solution of sulfobutylether-?-cyclodextrin (SBECD); controlling the temperature of said solution to a temperature of from 2 to 15° C.; adding the flurane to the aqueous solution; allowing the solution to react to produce the complex; and separating the complex.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: October 2, 2018
    Assignee: Sapiotec GmbH
    Inventors: Norbert Roewer, Jens Broscheit
  • Patent number: 9949947
    Abstract: The invention relates to a composition comprising a complex of delphinidin and a sulfoalkyl ether-?-cyclodextrin for use in the treatment of malignant melanoma.
    Type: Grant
    Filed: November 28, 2013
    Date of Patent: April 24, 2018
    Assignee: SAPIOTEC GMBH
    Inventors: Norbert Roewer, Jens Broscheit
  • Patent number: 9925274
    Abstract: The invention relates to a composition comprising a complex of delphinidin and a sulfoalkyl ether ?-cyclodextrin for use as an antiphlogistic and/or immunosuppressive.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: March 27, 2018
    Assignee: SAPIOTEC GMBH
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20170239171
    Abstract: The Invention relates to an oromucosal film preparation. According to the invention, said oromucosal film preparation comprises an active-ingredient containing surface area (3) and an active-ingredient free surface area (4). Said surface area (4) which is free of active-ingredients can be used as an application aid for the safe and simple application of the film preparation.
    Type: Application
    Filed: September 22, 2015
    Publication date: August 24, 2017
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20170065537
    Abstract: The invention relates to a method for producing a flurane complex, comprising the following steps: producing an aqueous solution of sulfobutylether-?-cyclodextrin (SBECD); controlling the temperature of said solution to a temperature of from 2 to 15° C.; adding the flurane to the aqueous solution; allowing the solution to react to produce the complex; and separating the complex.
    Type: Application
    Filed: February 26, 2015
    Publication date: March 9, 2017
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20170014377
    Abstract: The invention relates to a complex of an anthocyanidin and a methylated ?-cyclodextrin which can be formulated as an aqueous solution and as a solid, and to a process for the preparation of such a complex. Complexes according to the invention are storage-stable and can be readily formulated in aqueous solution.
    Type: Application
    Filed: February 26, 2015
    Publication date: January 19, 2017
    Inventors: Norbert Roewer, Jens Broscheit
  • Patent number: 9511047
    Abstract: The invention relates to a composition comprising: a complex of delphinidin and a sulfoalkyl ether-?-cyclodextrin and/or delphinidin and the salts thereof as a first component; and a tumour-necrosis factor related apoptosis-inducing ligand (TRAIL) as a second component, for use in the treatment of malignant melanoma.
    Type: Grant
    Filed: November 28, 2013
    Date of Patent: December 6, 2016
    Assignee: SAPIOTEC GMBH
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20150328336
    Abstract: The invention relates to a composition comprising a complex of delphinidin and a sulfoalkyl ether-?-cyclodextrin for use in the treatment of malignant melanoma.
    Type: Application
    Filed: November 28, 2013
    Publication date: November 19, 2015
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20150320719
    Abstract: The invention relates to a composition comprising: a complex of delphinidin and a sulfoalkyl ether-?-cyclodextrin and/or delphinidin and the salts thereof as a first component; and a tumour-necrosis factor related apoptosis-inducing ligand (TRAIL) as a second component, for use in the treatment of malignant melanoma.
    Type: Application
    Filed: November 28, 2013
    Publication date: November 12, 2015
    Inventors: Norbert ROEWER, Jens BROSCHEIT
  • Publication number: 20150306247
    Abstract: The invention relates to a composition comprising a complex of delphinidin and a sulfoalkyl ether ?-cyclodextrin for use as an antiphlogistic and/or immunosuppressive.
    Type: Application
    Filed: November 1, 2013
    Publication date: October 29, 2015
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20150258202
    Abstract: The subject matter of the invention is a complex of delphinidin and a sulfoalkyl ether ?-cyclodextrin for use as a medicinal drug, in particular in the treatment of multiple myeloma.
    Type: Application
    Filed: October 17, 2013
    Publication date: September 17, 2015
    Inventors: Norbert Roewer, Jens Broscheit
  • Patent number: 9125953
    Abstract: The invention relates to a complex made of ?-cyclodextrin and a halogenated ether, characterized by a content of the halogenated ether of at least 3 wt % of the total weight of the complex.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: September 8, 2015
    Assignee: SAPIOTEC GMBH
    Inventors: Norbert Roewer, Jens Broscheit
  • Patent number: 9006215
    Abstract: The invention relates to a pharmaceutical formulation that contains a complex of a propofol salt with a cyclodextrin. The invention makes it possible to provide propofol in a formulation that can be stored and that can be administered intravenously without problems.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: April 14, 2015
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20150087822
    Abstract: The invention relates to a complex of pure anthocyanidin and a sulfoalkyl ether ?-cyclodextrin, which complex can be formulated as an aqueous solution and as a solid, and a method for producing such a complex. Complexes according to the invention are storage-stable and can be well formulated as an aqueous solution.
    Type: Application
    Filed: March 28, 2013
    Publication date: March 26, 2015
    Inventors: Norbert Roewer, Jens Broscheit
  • Patent number: 8980882
    Abstract: The invention relates to a pharmaceutical preparation for applying a pharmaceutical agent. According to the invention, the preparation contains: a) a pharmaceutical agent which has an aromatic group or an aromatic part and the molecule of which has a maximum diameter of ?2 nm; b) a permethylated cyclodextrin having a degree of substitution of 3 methyl groups per glucopyranose unit. The permethylated cyclodextrin and the pharmaceutical agent form a complex.
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: March 17, 2015
    Inventors: Norbert Roewer, Jens Broscheit
  • Publication number: 20150051273
    Abstract: The invention relates to the use of delphinidin or salts thereof, which is aimed at bacteria selected from the group comprising antibiotic-resistant Staphylococcus aureus and antibiotic-sensitive Staphylococcus aureus and at least partially neutralizes said bacteria, and methods for treating objects with delphinidin or salts thereof.
    Type: Application
    Filed: March 28, 2013
    Publication date: February 19, 2015
    Inventors: Norbert Roewer, Jens Broscheit