Patents by Inventor Jens Chr. Norrild

Jens Chr. Norrild has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of compounds modifying a cellular response
    Patent number: 9150899
    Abstract: The present invention relates to methods for identifying compounds capable of modulating a cellular response. The methods involve attaching living cells to solid supports comprising a library of test compounds. The test compounds are linked to the solid support via cleavable linkers and may thus be released from the solid supports. Solid supports comprising cells, wherein the cellular response of interest has been modulated are selected and the test compound of the solid support can then be identified. The cellular response may for example be changes in complex formation between proteins.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: October 6, 2015
    Assignee: 2cureX
    Inventors: Ole Thastrup, Morten Meldal, Grith Hagel, Jens Chr. Norrild, Morten Hentzer
  • IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE
    Publication number: 20130123140
    Abstract: The present invention relates to methods for identifying compounds capable of modulating a cellular response. The methods involve attaching living cells to solid supports comprising a library of test compounds. The test compounds are linked to the solid support via cleavable linkers and may thus be released from the solid supports. Solid supports comprising cells, wherein the cellular response of interest has been modulated are selected and the test compound of the solid support can then be identified. The cellular response may for example be changes in complex formation between proteins.
    Type: Application
    Filed: April 6, 2012
    Publication date: May 16, 2013
    Applicant: 2cureX
    Inventors: Ole Thastrup, Morten Meldal, Grith Hagel, Jens Chr. Norrild, Morten Hentzer
  • Compounds modifying apoptosis
    Patent number: 8318717
    Abstract: The present invention relates to compounds capable of inhibiting binding of the Smac protein to Inhibitors of apoptosis (IAPs). Such compounds are preferably capable of inhibiting IAP and thus may promote apoptosis or sensitize cells for apoptosis. The compounds may be used in the treatment of proliferative diseases, such as cancer.
    Type: Grant
    Filed: May 23, 2006
    Date of Patent: November 27, 2012
    Assignee: 2cureX
    Inventors: Ole Thastrup, Jens Chr. Norrild
  • Identification of Compounds Modifying A Cellular Response
    Publication number: 20090239755
    Abstract: The present invention relates to methods for identifying compounds capable of modulating a cellular response. The methods involve attaching living cells to solid supports comprising a library of test compounds. The test compounds are linked to the solid support via cleavable linkers and may thus be released from the solid supports. Solid supports comprising cells, wherein the cellular response of interest has been modulated are selected and the test compound of the solid support can then be identified. The cellular response may for example be changes in complex formation between proteins.
    Type: Application
    Filed: May 25, 2005
    Publication date: September 24, 2009
    Applicant: 2cureX
    Inventors: Ole Thastrup, Morten Meldal, Grith Hagel, Jens Chr. Norrild, Morten Hentzer
  • Compounds Modifying Apoptosis
    Publication number: 20080194537
    Abstract: The present invention relates to compounds capable of inhibiting binding of the Smac protein to Inhibitors of apoptosis (IAPs). Such compounds are preferably capable of inhibiting IAP and thus may promote apoptosis or sensitize cells for apoptosis. The compounds may be used in the treatment of proliferative diseases, such as cancer.
    Type: Application
    Filed: May 23, 2006
    Publication date: August 14, 2008
    Inventors: Ole Thastrup, Jens Chr. Norrild