Patents by Inventor Jens-Dietmar Heinrich

Jens-Dietmar Heinrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 2,2-difluoroethylamine starting from a benzylamine compound
    Patent number: 8450528
    Abstract: Process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2??(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the general formula (II) CHF2—CH2Hal??(II), with a benzylamine compound of the formula (III) in the presence of an acid scavenger, in which, in formula (II), Hal is chlorine, bromine or iodine, and, in the formulae (III), R1 is hydrogen or C1-C12-alkyl, and R2 is hydrogen, halogen, C1-C12-alkyl or C1-C6-alkoxy; stage (ii): catalytic hydrogenation of the N-benzyl-2,2-difluoroethanamine compound obtained in the stage (i) to give 2,2-difluoroethylamine of the formula (I) or a salt thereof.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: May 28, 2013
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich, Christian Funke, Günter Schlegel, Thomas Norbert Müller
  • PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 1-ALKYLTETRAZOLES
    Publication number: 20120330027
    Abstract: The present invention relates to a process for the preparation of 5-substituted 1-alkyltetrazoles.
    Type: Application
    Filed: March 11, 2011
    Publication date: December 27, 2012
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Stephane Caillon-Morisseau, Pierre-Yves Coqueron, Jens-Dietmar Heinrich, Robert Lui
  • METHOD FOR PREPARING 4-AMINOBUT-2-ENOLIDES
    Publication number: 20120323023
    Abstract: Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are reduced to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A radical is as defined in the description:
    Type: Application
    Filed: August 22, 2012
    Publication date: December 20, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Jens-Dietmar HEINRICH
  • Method for producing 2,2-difluoroethylamine derivatives by imine hydrogenation
    Patent number: 8324393
    Abstract: Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are hydrogenated to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A radical is as defined in the description:
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: December 4, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich
  • Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates
    Patent number: 8318955
    Abstract: Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates of the formula (I) and/or (I?) comprising the reaction of a haloacetyl chloride compound of the formula (II) with a malonic ester of the formula (III) in which Hal, R1 and R2 have the definitions stated in the application, in the presence of a suitable base and optionally in the presence of a solvent; the addition of a sufficient amount of water to the reaction mixture; and the isolation of the desired 2,4-dioxotetrahydrofuran-3-carboxylate.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: November 27, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich, Christian Funke
  • Process for the preparation of 4-aminobut-2-enolides
    Patent number: 8314242
    Abstract: Process for the preparation of 4-aminobut-2-enolide compounds of the formula (I): comprising reaction of a 4-(methylamino)furan-2(5H)-one compound of the formula (II) with an amine of the formula (III) in which R1 and A have the definitions mentioned in the description, optionally in the presence of a Brønstedt acid.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: November 20, 2012
    Assignee: BayerCrop Science AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich
  • Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives
    Patent number: 8288582
    Abstract: The present invention relates to a process for preparing 2-fluoroacyl-3-aminoacrylic acid derivatives by reacting fluorinated carboxylic acids with dialkylaminoacrylic acid derivatives and acid halides.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: October 16, 2012
    Assignee: Bayer CropScience AG
    Inventors: Norbert Lui, Thomas Wollner, Jürgen Wieschmeyer, Michael Dockner, Jens-Dietmar Heinrich
  • Method for preparing 4-aminobut-2-enolides
    Patent number: 8273904
    Abstract: Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are reduced to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A radical is as defined in the description:
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: September 25, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich
  • PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE
    Publication number: 20120190867
    Abstract: A process for the preparation of 2,2-difluoroethylamine, comprising the reaction of 2,2-difluoro-1-chloroethane with an imide of the formula (II) in the presence of an acid scavenger, to give a compound of the formula (III) in which, in the compounds of the formulae (II) and (III), R1 and R2 are, each independently of one another, hydrogen or C1-C6-alkyl or R1 and R2 form, together with the carbon atoms to which they are bonded, a six-membered aromatic ring which is optionally substituted; and the cleavage of 2,2-difluoroethylamine by reaction of the compound of the formula (III) with acid, base or hydrazine.
    Type: Application
    Filed: January 23, 2012
    Publication date: July 26, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Jens-Dietmar HEINRICH
  • Process for preparing fluoroalkyl nitriles
    Patent number: 8203015
    Abstract: The present invention relates to a process for preparing fluoroalkyl nitriles by reacting fluorinated carboxamides with halides and fluorinated carboxylic acids.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: June 19, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich, Thomas Wollner, Sergii Pazenok
  • PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM PROP-2-EN-1-AMINE
    Publication number: 20120142971
    Abstract: A process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2??(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the formula (II) CHF2—CH2Hal??(II) in which Hal is chlorine, bromine or iodine, with prop-2-en-1-amine of the formula (III) to give N-(2,2-difluoroethyl)prop-2-en-1-amine of the formula (IV) preferably in the presence of an acid scavenger, and stage (ii): removal of the allyl group from the N-(2,2-difluoroethyl)prop-2-en-1-amine of the formula (IV) obtained in stage (i) to give 2,2-difluoroethylamine of the formula (I) or a salt thereof.
    Type: Application
    Filed: November 9, 2011
    Publication date: June 7, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Christian FUNKE, Jens-Dietmar HEINRICH, Thomas Norbert MÜLLER
  • PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE DERIVATIVES STARTING FROM N-(2,2-DIFLUOROETHYL)PROP-2-EN-1-AMINE
    Publication number: 20120123130
    Abstract: Process for the preparation of 2,2-difluoroethylamine derivatives of the formula (IV) comprising the steps (i) and (ii): step (i): reaction of N-(2,2-difluoroethyl)prop-2-en-1-amine of the formula (I) with a compound of the formula (II) A-CH2-E??(II) to give a compound of the formula (III) optionally in the presence of an inorganic or organic base, and step (ii): removal of the allyl group from the compound of the formula (III), in which, in the formulae (II), (III) and (IV), A and E have the meanings given in the description.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 17, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Jens-Dietmar HEINRICH
  • PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND
    Publication number: 20120123163
    Abstract: Process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2??(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the general formula (II) CHF2—CH2Hal??(II), with a benzylamine compound of the formula (III) in the presence of an acid scavenger, in which, in formula (II), Hal is chlorine, bromine or iodine, and, in the formulae (III), R1 is hydrogen or C1-C12-alkyl, and R2 is hydrogen, halogen, C1-C12-alkyl or C1-C6-alkoxy; stage (ii): catalytic hydrogenation of the N-benzyl-2,2-difluoroethanamine compound obtained in the stage (i) to give 2,2-difluoroethylamine of the formula (I) or a salt thereof.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 17, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Jens-Dietmar HEINRICH, Christian FUNKE, Günter SCHLEGEL, Thomas Norbert Müller
  • NOVEL METHOD FOR PRODUCING ENAMINOCARBONYL COMPOUNDS
    Publication number: 20120016132
    Abstract: The present invention relates to a process for the preparation of enaminocarbonyl compounds of the formula (I) where compounds of the formula (II) are reacted in the presence of a Brønsted acid to give compounds of the formula (I), and A, R1 and Z are as defined in the description, and also corresponding starting compounds which are used in the process according to the invention.
    Type: Application
    Filed: March 12, 2010
    Publication date: January 19, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich
  • NOVEL METHOD FOR PRODUCING ENAMINOCARBONYL COMPOUNDS
    Publication number: 20120004416
    Abstract: The present invention relates to a process for preparing enaminocarbonyl compounds by reacting compounds of the formula (II) with compounds of the formula (III) in which the A, R1, R2 and Z radicals are each as defined in the description, in the presence of a Brønsted acid.
    Type: Application
    Filed: March 12, 2010
    Publication date: January 5, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich
  • Process for preparing 2-2-difluoroethylamine derivatives by alkylation with 2-2-difluoroethyl-1-haloethanes
    Publication number: 20110306770
    Abstract: Process for preparing 2,2-difluorethylamine derivatives of the general formula (III) in which A is an optionally substituted heterocycle as described in the description, by reacting a 2,2-difluoroethyl-1-haloethane compound of the general formula (I) in which Hal is Cl, Br or iodine, with an amine of the general formula (II) in which A is as defined above, optionally in the presence of a base.
    Type: Application
    Filed: June 13, 2011
    Publication date: December 15, 2011
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Jens-Dietmar HEINRICH, Wahed Ahmed MORADI, Christian FUNKE
  • Process for Preparing Dithiine-tetracarboxy-diimides
    Publication number: 20110275831
    Abstract: The present invention relates to a new process for preparing dithiine-tetracarboxy-diimides
    Type: Application
    Filed: May 5, 2011
    Publication date: November 10, 2011
    Applicant: Bayer CropScience AG
    Inventors: Norbert LUI, Jens-Dietmar HEINRICH, Thomas Himmler, Frank Volz
  • Method for producing substituted pyrazolecarboxylic acid chlorides
    Patent number: 7977494
    Abstract: The present invention relates to a process for preparing substituted pyrazolyl chlorides by chlorinating aldehydes of the formula (II) under free-radical conditions.
    Type: Grant
    Filed: January 9, 2008
    Date of Patent: July 12, 2011
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich, Alexander Straub, Thomas Wollner, James Mark Ford
  • Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates
    Publication number: 20110060147
    Abstract: Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates of the formula (I) and/or (I?) comprising the reaction of a haloacetyl chloride compound of the formula (II) with a malonic ester of the formula (III) in which Hal, R1 and R2 have the definitions stated in the application, in the presence of a suitable base and optionally in the presence of a solvent; the addition of a sufficient amount of water to the reaction mixture; and the isolation of the desired 2,4-dioxotetrahydrofuran-3-carboxylate.
    Type: Application
    Filed: August 11, 2010
    Publication date: March 10, 2011
    Applicant: Bayer CropScience AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich, Christian Funke
  • Novel Process for the Preparation of 4-Aminobut-2-enolides
    Publication number: 20110054182
    Abstract: Process for the preparation of 4-aminobut-2-enolide compounds of the formula (I): comprising reaction of a 4-(methylamino)furan-2(5H)-one compound of the formula (II) with an amine of the formula (III) in which R1 and A have the definitions mentioned in the description, optionally in the presence of a Brønstedt acid.
    Type: Application
    Filed: August 17, 2010
    Publication date: March 3, 2011
    Applicant: Bayer CropScience AG
    Inventors: Norbert LUI, Jens-Dietmar Heinrich