Patents by Inventor Jens Hyldig-Nielsen

Jens Hyldig-Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11111525
    Abstract: This invention is directed to methods, kits, non-nucleotide probes as well as other compositions pertaining to the suppression of binding of detectable nucleic acid probes to undesired nucleotide sequences of genomic nucleic acid in assays designed to determine target genomic nucleic acid.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: September 7, 2021
    Assignees: Applied Biosystems, LLC, Agilent Technologies, Inc.
    Inventors: Kirsten Vang Nielsen, Jens Hyldig-Nielsen, Brett F. Williams
  • Publication number: 20180312912
    Abstract: This invention is directed to methods, kits, non-nucleotide probes as well as other compositions pertaining to the suppression of binding of detectable nucleic acid probes to undesired nucleotide sequences of genomic nucleic acid in assays designed to determine target genomic nucleic acid.
    Type: Application
    Filed: March 19, 2018
    Publication date: November 1, 2018
    Inventors: Kirsten Vang NIELSEN, Jens HYLDIG-NIELSEN, Brett F. WILLIAMS
  • Patent number: 9951377
    Abstract: This invention is directed to methods, kits, non-nucleotide probes as well as other compositions pertaining to the suppression of binding of detectable nucleic acid probes to undesired nucleotide sequences of genomic nucleic acid in assays designed to determine target genomic nucleic acid.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: April 24, 2018
    Assignees: APPLIED BIOSYSTEMS, LLC, DAKO DENMARK A/S
    Inventors: Kirsten Vang Nielson, Jens Hyldig-Nielsen, Brett F. Williams
  • Publication number: 20140378326
    Abstract: This invention is directed to methods, kits, non-nucleotide probes as well as other compositions pertaining to the suppression of binding of detectable nucleic acid probes to undesired nucleotide sequences of genomic nucleic acid in assays designed to determine target genomic nucleic acid.
    Type: Application
    Filed: June 13, 2014
    Publication date: December 25, 2014
    Inventors: Kirsten NIELSON, Jens Hyldig-Nielsen, Brett F. Williams
  • Patent number: 8753821
    Abstract: This invention is related to PNA probes, probe sets, mixtures, methods and kits pertaining to the determination of Mycoplasma and related Mollicutes.
    Type: Grant
    Filed: February 20, 2012
    Date of Patent: June 17, 2014
    Assignee: Applied Biosystems, LLC
    Inventors: Jens Hyldig-Nielsen, Susan Rigby, Michael Tanner, Ditte Lee, Byron Brehm-Stecher
  • Publication number: 20070249001
    Abstract: The present invention generally relates to the detection of analytes, particularly biomolecules in samples. The invention also relates to compositions, methods, and kits for detecting the presence of analytes, typically in multiplex detection formats. The invention also relates to methods for determining the presence of at least one analyte in a sample, the methods employing employ single molecule detection techniques to individually detect at least one molecular complex or at least part of a molecular complex.
    Type: Application
    Filed: March 23, 2007
    Publication date: October 25, 2007
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Dar Bahatt, Muhammad Sharaf, Timothy Liu, Serguei Ermakov, Charles Connell, Jens Hyldig-Nielsen
  • Publication number: 20070178471
    Abstract: This invention is directed to methods for determining amplified nucleic acid using Linear Beacons.
    Type: Application
    Filed: June 30, 2003
    Publication date: August 2, 2007
    Inventors: Brian Gildea, James Coull, Jens Hyldig-Nielsen, Mark Fiandaca
  • Publication number: 20070105145
    Abstract: This invention pertains to the field of combination oligomers, including the block synthesis of combination oligomers in the absence of a template, as well as related methods, kits, libraries and other compositions.
    Type: Application
    Filed: December 26, 2006
    Publication date: May 10, 2007
    Applicant: Applera Corporation
    Inventors: James Coull, Mark Fiandaca, Mark Kristjanson, Jens Hyldig-Nielsen, Theresa Creasey
  • Publication number: 20060252081
    Abstract: This invention is related to PNA probes, probe sets, mixtures, methods and kits pertaining to the determination of Mycoplasma and related Mollicutes.
    Type: Application
    Filed: May 4, 2006
    Publication date: November 9, 2006
    Applicant: Applera Corporation
    Inventors: Jens Hyldig-Nielsen, Susan Rigby, Byron Brehm-Stecher, Ditte Lee, Michael Tanner
  • Publication number: 20060003332
    Abstract: This invention is related to multiplex PNA-FISH assays.
    Type: Application
    Filed: July 31, 2003
    Publication date: January 5, 2006
    Inventors: Jens Hyldig-Nielsen, James Coull
  • Publication number: 20050164262
    Abstract: This invention is related to novel probes, probe sets, methods and kits pertaining to the detection of bacteria of the Salmonella genus. The probes, probe sets, methods and kits of this invention are particularly useful for the detection, identification and/or enumeration of bacteria of the Salmonella genus. It is an advantage of the identified probes that they do not substantially cross react with bacteria of the closely related Citrobacter genus. Preferably, the probes of this invention are prepared as PNA probes and most preferably the probing nucleobase sequence comprises a segment that is at least ninety percent homologous to the nucleobase sequence; GTG-TTA-AAG-TGA-ACC (Seq. Id. No. 1), AGC-CTT-GAT-TTT-CCG (Seq. Id. No. 2) or ACC-TAC-GTG-TCA-GCG (Seq. Id. No. 3).
    Type: Application
    Filed: January 4, 2005
    Publication date: July 28, 2005
    Applicant: Boston Probes, Inc.
    Inventor: Jens Hyldig-Nielsen
  • Publication number: 20050123959
    Abstract: Described herein are methods and kits that employ multiple probe sets in combination with sequential steps of hybridization analysis for multiplex analysis and/or detection of nucleic acids having one or more distinguishable target sequences.
    Type: Application
    Filed: September 29, 2004
    Publication date: June 9, 2005
    Inventors: Brett Williams, Jack Johansen, Jens Hyldig-Nielsen
  • Publication number: 20050123975
    Abstract: Embodiments of this invention are directed to methods for determining or estimating the concentration of nucleic acid or the state of degradation of nucleic acid in a sample of interest.
    Type: Application
    Filed: November 19, 2004
    Publication date: June 9, 2005
    Applicant: Applera Corporation
    Inventors: Lori Hennessy, Jens Hyldig-Nielsen
  • Publication number: 20050074774
    Abstract: The present invention generally relates to the detection of analytes, particularly biomolecules in samples. The invention also relates to compositions, methods, and kits for detecting the presence of analytes, typically in multiplex detection formats. The invention also relates to methods for determining the presence of at least one analyte in a sample, the methods employing employ single molecule detection techniques to individually detect at least one molecular complex or at least part of a molecular complex.
    Type: Application
    Filed: August 29, 2003
    Publication date: April 7, 2005
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Dar Bahatt, Muhammad Sharaf, Timothy Liu, Serguei Ermakov, Charles Connell, Jens Hyldig-Nielsen
  • Publication number: 20050069895
    Abstract: The teachings herein generally relates to probes comprising fabricated coded molecular tags for detecting analytes. The teachings also relate to compositions, methods, and kits for fabricating coded molecular tags comprising a multiplicity or reporter groups in an ordered pattern.
    Type: Application
    Filed: August 29, 2003
    Publication date: March 31, 2005
    Applicant: Applera Corporation
    Inventors: Timothy Woudenberg, Dar Bahatt, Muhammad Sharaf, Timothy Liu, Serguei Ermakov, Charles Connell, Jens Hyldig-Nielsen, Benjamin Schroeder, Paolo Vatta