Patents by Inventor Jens J. Holst

Jens J. Holst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of GLP-2 in a combination treatment for bone-related disorders
    Publication number: 20080249016
    Abstract: The present invention relates to methods of treatment of patients having an undesirably low bone mass or an undesirably high rate of bone resorption or an undesirably low rate of bone formation, which method comprises administering to the patient a therapeutically effective amount of each of: a) a first active component which promotes bone formation and promotes bone resorption, e.g. PTH; and b) a second active component which is a GLP-2, or a variant, an analogue, or derivative, or mimic of GLP-2 having the ability to bind and activate a GLP-2 receptor, or is a GLP-2 receptor agonist.
    Type: Application
    Filed: April 9, 2008
    Publication date: October 9, 2008
    Inventors: Dennis B. Henriksen, Jens J. Holst
  • Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders
    Patent number: 7186683
    Abstract: The present invention relates to methods for prevention and treatment of bone-related or nutrition-related disorders using a GLP molecule or GLP activator either alone or in combination with another therapeutic. The present invention also encompasses methods of diagnosing or monitoring the progression of a disorder. The invention also encompasses methods of monitoring the effectiveness of treatment of the invention.
    Type: Grant
    Filed: March 20, 2003
    Date of Patent: March 6, 2007
    Assignee: Sanos Bioscience A/S
    Inventors: Dennis B. Henriksen, Jens J. Holst
  • Method of inhibiting bone resorption and/or promoting bone formation using GLP-2 and related compounds
    Patent number: 6943151
    Abstract: Disclosed are methods of inhibiting bone resorption and/or promoting bone formation using GLP-2 and related Compounds. The invention has a wide spectrum of important uses including hyperparathyroidism, Paget's disease, hypercalcemia of malignancy, osteolytic lesions produced by bone metastasis, bone loss due to immobilisation or sex hormone deficiency, osteomalacia, hyperostosis and osteopetrosis.
    Type: Grant
    Filed: March 18, 2003
    Date of Patent: September 13, 2005
    Assignee: Sanos Bioscience A/S
    Inventors: Dennis B. Henriksen, Jens J. Holst
  • GLP-1 as a diagnostic test to determine ?-cell function and the presence of the condition of IGT and type-II diabetes
    Patent number: 6884579
    Abstract: Since glucagon-like peptide-1 (GLP-1) is the most potent insulinotropic hormone known and has been shown to stimulate insulin secretion strongly in patients with type II diabetes, this invention uses GLP-1 or its biologically active analogues in ?-cell stimulatory tests in order to test ?-cell function in a simple way. The test provides information about insulin secretory capacity, is easy and reproducible and has insignificant side effects.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: April 26, 2005
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: Jens J. Holst, Tina Vilsboll
  • Use of GLP-1 and GLP-2 peptides
    Publication number: 20040082507
    Abstract: Glucagon-like peptide-1 (GLP-1) and/or a glucagon-like peptide-2 (GLP-2) or an analogue or derivative is proposed for use in inhibiting bone resorption or for promoting bone formation.
    Type: Application
    Filed: March 18, 2003
    Publication date: April 29, 2004
    Inventors: Dennis B. Henriksen, Jens J. Holst
  • Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders
    Publication number: 20040052862
    Abstract: The present invention relates to methods for prevention and treatment of bone-related or nutrition-related disorders using a GLP molecule or GLP activator either alone or in combination with another therapeutic. The present invention also encompasses methods of diagnosing or monitoring the progression of a disorder. The invention also encompasses methods of monitoring the effectiveness of treatment of the invention.
    Type: Application
    Filed: March 20, 2003
    Publication date: March 18, 2004
    Inventors: Dennis B. Henriksen, Jens J. Holst