Patents by Inventor Jens Niewoehner

Jens Niewoehner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies specifically binding to human TSLPR and methods of use
    Publication number: 20120020988
    Abstract: An antibody specifically binding to human thymic stromal lymphopoietin receptor (TSLPR), characterized in comprising as heavy chain variable domain CDR regions a CDR1 region of SEQ ID NO:2 or 17, a CDR2 region of SEQ ID NO:3 or 10, and CDR3 region of SEQ ID NO:4, and as light chain variable domain CDR regions a CDR1 region of SEQ ID NO:6 or 12, a CDR2 region of SEQ ID NO:7, 13 or 15, and a CDR3 region of SEQ ID NO:8. is useful for the treatment of immunological diseases.
    Type: Application
    Filed: July 15, 2011
    Publication date: January 26, 2012
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: JOHANNES AUER, MARIA FUENTES, GUY GEORGES, HUBERT KETTENBERGER, HANS-WILLI KRELL, JENS NIEWOEHNER, GEORG TIEFENTHALER
  • Antibodies against human tweak and uses thereof
    Patent number: 8093006
    Abstract: An antibody binding to TWEAK comprising as heavy chain variable domain a CDR3H selected from the group consisting of SEQ ID NO: 8, 16 or 24.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: January 10, 2012
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Monika Baehner, Hendrik Knoetgen, Jens Niewoehner
  • FUEL TANK
    Publication number: 20110240389
    Abstract: A fuel tank of a motor vehicle is mounted on a body structure of the motor vehicle via fastening elements. The fuel tank has a glass fiber reinforced shaped plastic part (12) as heat shield that at least partially covers a surface of the fuel tank and is mounted with the fuel tank on the body structure of the motor vehicle via the fastening elements.
    Type: Application
    Filed: February 17, 2011
    Publication date: October 6, 2011
    Applicant: DR. ING. H.C.F. PORSCHE AKTIENGESELLSCHAFT
    Inventors: Jens Niewoehner, Alexander Kiessling, Werner Speck
  • AXL ANTIBODIES
    Publication number: 20100330095
    Abstract: The present invention refers to antibodies, particularly to monoclonal antibodies, which bind to the extracellular domain of the AXL receptor tyrosine kinase and which at least partially inhibit AXL activity.
    Type: Application
    Filed: November 12, 2008
    Publication date: December 30, 2010
    Applicant: U3 PHARMA GMBH
    Inventors: Thore Hettmann, Jens Niewoehner, Jens Ruhe, Peter Wirtz, Kerstin Selle, Esther Zwick-Wallasch, Mike Rothe
  • Antibodies Against Human CCN1 and Uses Thereof
    Publication number: 20100310567
    Abstract: Disclosed herein are methods for the recombinant expression of mammalian cell membrane-bound human CCN1 or a CCN1 domain thereof in mammalian cells, comprising transforming a mammalian host cell with a vector encoding CCN1 or a CCN1 domain thereof C-terminally fused to a mammalian cell transmembrane domain (CCN1 fusion protein), expressing said CCN1 or CCN1 domain fusion protein in said host cell, and recovering said membrane bound CCN1 or said CCN1 domain thereof. Disclosed herein is the use of such membrane bound CCN1 and domain for the generation of corresponding antibodies. Antibodies against human CCN1 are useful for the treatment of diseases.
    Type: Application
    Filed: June 3, 2010
    Publication date: December 9, 2010
    Inventors: HENDRIK KNOETGEN, HANS-WILLI KRELL, SANDRA MILLER, JENS NIEWOEHNER, DIRK PONSEL, ENGIN TOKSOEZ
  • ANTIBODIES AGAINST HUMAN TWEAK AND USES THEREOF
    Publication number: 20100255008
    Abstract: An antibody binding to TWEAK comprising as heavy chain variable domain a CDR3H selected from the group consisting of SEQ ID NO: 8, 16 or 24.
    Type: Application
    Filed: March 29, 2010
    Publication date: October 7, 2010
    Inventors: Monika Baehner, Hendrik Knoetgen, Jens Niewoehner
  • FGFR4 ANTIBODIES
    Publication number: 20100169992
    Abstract: The present invention relates to FGFR4 antibodies including fragments or derivatives thereof and the polynucleotides encoding the antibodies. Expression vectors and host cells comprising the polynucleotides are provided. Further, the invention refers to pharmaceutical compositions comprising the FGFR4 antibodies and methods for the treatment, prevention or diagnosis of disorders associated with FGFR4 expression.
    Type: Application
    Filed: November 2, 2007
    Publication date: July 1, 2010
    Inventors: Johannes Bange, Jens Niewoehner, Patricia Aus Dem Siepen, Mike Rothe