Abstract: The fuel injector according to the invention is distinguished in that a particularly high structural strength and vibration resistance of the valve seat body (5) is provided. The fuel injector (1) includes an excitable actuator for actuating a valve closing body, which forms a seal seat together with a valve seat surface (6) formed on a valve seat body (5), and injection openings (7), which are formed downstream of the valve seat surface (6), the injection openings (7) being introduced into a middle area (44) of the valve seat body (5) protruding outwardly like a cone in the injection direction. The cone-like axially protruding middle area (44) of the valve seat body (5) ends radially outside the orifice areas of all injection openings (7) in a recessed depression (47), from which, in turn, an axially protruding border area (48) of the valve seat body (5) adjoins radially outwardly, so that an overall wavy cone contour of the valve seat body (5) is formed in cross section.

Abstract: A system, which is used especially as a fuel injection system for the high-pressure injection in internal combustion engines, includes a fuel distributor and a plurality of fuel injectors. Each fuel injector is situated on a cup of the fuel distributor. At least one of the fuel injectors is fastened to the associated cup by a holding element. The holding element has an at least essentially straight first leg and an at least essentially straight second leg. The cup includes at least one recess, which extends through a wall of the cup. The first leg and the second leg are guided through the at least one recess. Furthermore, the connection sleeve of the fuel injector has a collar, which is braced on the first leg of the holding element and on the second leg of the holding element in order to secure the fuel injector on the cup.

Abstract: Disclosed are compounds of formula (I) wherein A is CH or N, B is CR or N; and D is CR; R represents hydrogen, OH or NH2; R1 and R2, independently of each other, represent hydrogen, N(R3)2, halogen, cyano, nitro, R4-C1-C4alkyl, R4-C1-C4halogenoalkyl, OH, R4-C1-C4alkoxy, R4-C1-C4halogenoalkoxy, SH, R4-C1-C4alkythio, R4-C1-C4halogenoalkylthio; R3 represents, independently at each occurrence, hydrogen, R4-C1-C4alkyl or R4-C1-C4halogenoalkyl; R3a represents, independently at each occurrence, hydrogen or C1-C4 alkyl; R4 represents, independently at each occurrence, hydrogen, halogen, cyano, OH, SH, NH2, NH(CH3) or N(CH3)2; X represents a group of formula -E- or -E-F—, wherein E and F are different from each other and represent a group selected from —C(R3a)2-, —(C?O)—, —NR3a- and —O— and F is linked to Y, with the proviso that if X represents -E-F— one of E or F represents —C(R3a)2— or —(C?O)—; Y represents a group selected from C1-C6alkyl, mono- or bicyclic C3-C11cycloalkyl, which may be partially unsaturated, mon

Abstract: Disclosed are compounds of formula (I) wherein A is CH or N, B is CR or N; and D is CR; R represents hydrogen, OH or NH2; R1 and R2, independently of each other, represent hydrogen, N(R3)2, halogen, cyano, nitro, R4-C1-C4alkyl, R4-C1-C4halogenoalkyl, OH, R4-C1-C4alkoxy, R4-C1-C4halogenoalkoxy, SH, R4-C1-C4alkythio, R4-C1-C4halogenoalkylthio; R3 represents, independently at each occurrence, hydrogen, R4-C1-C4alkyl or R4-C1-C4halogenoalkyl; R3a represents, independently at each occurrence, hydrogen or C1-C4 alkyl; R4 represents, independently at each occurrence, hydrogen, halogen, cyano, OH, SH, NH2, NH(CH3) or N(CH3)2; X represents a group of formula -E- or -E-F—, wherein E and F are different from each other and represent a group selected from —C(R3a)2-, —(C?O)—, —NR3a- and —O— and F is linked to Y, with the proviso that if X represents -E-F— one of E or F represents —C(R3a)2- or —(C?O)—; Y represents a group selected from C1-C6alkyl, mono- or bicyclic C3-C11cycloalkyl, which may be partially unsaturated, mon

Abstract: A connection piece for a valve, which is for metering a fluid, includes a sealing section, on which at least one annular sealing element is situated. The annular sealing element circumferentially surrounds the sealing section with respect to a longitudinal axis. In the connection piece, at least one support ring is situated on the sealing section, the support ring at least partially circumferentially surrounds the sealing section with respect to the longitudinal axis, the sealing section is configured, at least in one area along the longitudinal axis, in which the support ring surrounds the sealing section at least during operation, to have a circumference increasing in a direction along the longitudinal axis, and the support ring and the sealing section are configured so that, during operation, the support ring is displaceable in the direction in relation to the sealing section due to a fluid pressure of the fluid.

Abstract: A fuel injection system has a fuel distributor and multiple fuel injection valves each disposed on a cup of the fuel distributor. At least one injection valve is mounted on the associated cup by way of at least one holding element. An abutment surface is provided on the outer side of the cup. A support surface is configured on the underside of the cup. The holding element is moreover configured as a holding clamp. An abutment surface is provided on an outer side of the fuel injection valve. The holding clamp engages on the one hand behind the abutment surface of the cup and on the other hand behind the abutment surface of the fuel injection valve. The holding clamp furthermore pushes the fuel injection valve toward the support surface.

Abstract: A decoupling element is described for a fuel injection device which is characterized in particular by a low-noise design. The fuel injection device includes at least one fuel injector, a receiving bore in a cylinder head for the fuel injector, and the decoupling element between a valve housing of the fuel injector and a wall of the receiving bore. The decoupling element is designed as a decoupling system having a spring ring and a conical washer. The fuel injection device is suitable for injecting fuel into a combustion chamber of a mixture-compressing spark-ignition internal combustion engine in particular.

Abstract: Disclosed are compounds of formula (I) wherein A is CH or N, B is CR or N; and D is CR; R represents hydrogen, OH or NH2; R1 and R2, independently of each other, represent hydrogen, N(R3)2, halogen, cyano, nitro, R4-C1-C4alkyl, R4-C1-C4halogenoalkyl, OH, R4-C1-C4alkoxy, R4-C1-C4halogenoalkoxy, SH, R4-C1-C4alkythio, R4-C1-C4halogenoalkylthio; R3 represents, independently at each occurrence, hydrogen, R4-C1-C4alkyl or R4-C1-C4halogenoalkyl; R3a represents, independently at each occurrence, hydrogen or C1-C4 alkyl; R4 represents, independently at each occurrence, hydrogen, halogen, cyano, OH, SH, NH2, NH(CH3) or N(CH3)2; X represents a group of formula -E- or -E-F—, wherein E and F are different from each other and represent a group selected from —C(R3a)2-, —(C?O)—, —NR3a- and —O— and F is linked to Y, with the proviso that if X represents -E-F— one of E or F represents —C(R3a)2- or —(C?O)—; Y represents a group selected from C1-C6alkyl, mono- or bicyclic C3-C11cycloalkyl, which may be partially unsaturated, mon

Abstract: An electromagnetically actuatable valve is described, for controlling fluids, having an inner pole and a magnetic armature, the inner pole having a first end face oriented to the magnetic armature, and the magnetic armature having a second end face oriented to the inner pole, a first contact line and a second contact line being present between the first and second end face when the inner pole and the magnetic armature come into contact with one another, and a damping volume being present between the first and second contact line when the inner pole and the magnetic armature come into contact with one another.

Abstract: A system, which is used in particular as a fuel injection system for the high-pressure injection in internal combustion engines, includes a fuel distributor and a plurality of fuel injectors. Each fuel injector is situated on a cup of the fuel distributor. At least one of the fuel injectors is fastened to the associated cup by a holding element, which has a supporting surface. The cup has a contact surface on an underside, by way of which the cup is supported at the supporting surface of the holding element by a damping layer. The holding element is attached to the cup. In addition, the fuel injector has a collar, which is braced on the holding element. Because of the damping layer, vibrations are able to be dampened, and the noise transmissions is able to be reduced.

Abstract: The invention relates to novel Rauwolfia alkaloid derivatives of formula (I) combinations of Rauwolfia alkaloid derivatives and a mitochondrial inhibitor, e.g. metformin, and the use of Rauwolfia alkaloid derivatives in combination with mitochondrial inhibitor for the treatment of cancer and for achieving clinical immunosuppression. The invention also relates to a fluorescence-based method for predicting the sensitivity of a cancer cell towards a compound of formula (I).

Abstract: An electrically actuatable valve for injecting fuel includes a magnetic actuator having multiple components, at least one component of the magnetic actuator having multiple sectors made of soft magnetic material and multiple insulating separating webs. A separating web is situated between each two neighboring sectors and entirely separates the neighboring sectors from one another electrically.

Abstract: A valve for metering fluid includes: a flow channel, which leads from a fluid inlet to a metering opening for the fluid; and a filter device, which is situated in the flow channel, and through which the fluid flows. The filter device has a coarse filter and a fine filter which is situated downstream from the coarse filter in the flow direction of the fluid.

Abstract: A system, which is used especially as a fuel injection system for the high-pressure injection in internal combustion engines, includes a fuel distributor and a plurality of fuel injectors. Each fuel injector is situated on a cup of the fuel distributor. At least one of the fuel injectors is fastened to the associated cup by a holding element. The holding element has an at least essentially straight first leg and an at least essentially straight second leg. The cup includes at least one recess, which extends through a wall of the cup. The first leg and the second leg are guided through the at least one recess. Furthermore, the connection sleeve of the fuel injector has a collar, which is braced on the first leg of the holding element and on the second leg of the holding element in order to secure the fuel injector on the cup. This makes it possible to fasten the fuel injector on the cup in a reliable manner.

Abstract: A decoupling element is described for a fuel injection device which is characterized in particular by a low-noise design. The fuel injection device includes at least one fuel injector, a receiving bore in a cylinder head for the fuel injector, and the decoupling element between a valve housing of the fuel injector and a wall of the receiving bore. The decoupling element is designed as a decoupling system having a spring ring and a conical washer. The fuel injection device is suitable for injecting fuel into a combustion chamber of a mixture-compressing spark-ignition internal combustion engine in particular.

Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.

Abstract: The invention relates to novel Rauwolfia alkaloid derivatives of formula (I) combinations of Rauwolfia alkaloid derivatives and a mitochondrial inhibitor, e.g. metformin, and the use of Rauwolfia alkaloid derivatives in combination with mitochondrial inhibitor for the treatment of cancer and for achieving clinical immunosuppression. The invention also relates to a fluorescence-based method for predicting the sensitivity of a cancer cell towards a compound of formula (I).

Abstract: A fuel injection system has a fuel distributor and multiple fuel injection valves each disposed on a cup of the fuel distributor. At least one injection valve is mounted on the associated cup by way of at least one holding element. An abutment surface is provided on the outer side of the cup. A support surface is configured on the underside of the cup. The holding element is moreover configured as a holding clamp. An abutment surface is provided on an outer side of the fuel injection valve. The holding clamp engages on the one hand behind the abutment surface of the cup and on the other hand behind the abutment surface of the fuel injection valve. The holding clamp furthermore pushes the fuel injection valve toward the support surface.

Abstract: An electromagnetically actuatable valve is described, for controlling fluids, having an inner pole and a magnetic armature, the inner pole having a first end face oriented to the magnetic armature, and the magnetic armature having a second end face oriented to the inner pole, a first contact line and a second contact line being present between the first and second end face when the inner pole and the magnetic armature come into contact with one another, and a damping volume being present between the first and second contact line when the inner pole and the magnetic armature come into contact with one another.

Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.