Patents by Inventor Jens Schouenborg
Jens Schouenborg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20190240477Abstract: A proto microelectrode from which a micro electrode is formed in situ upon insertion into soft tissue comprises a flexible oblong electrode body of electrically conducting material having a front end and a rear end. The electrode body having a metal or a metal alloy or an electrically conducting form of carbon or an electrically conducting polymer or a combination thereof. A first coat of a water soluble and/or swellable and/or degradable material is disposed on the electrode body and extends along is at least over a distal portion thereof. A second coat of electrically insulating, water insoluble flexible polymer material is disposed on the first coat. The second coat comprises one or more through openings at or near its front end. Also disclosed is a corresponding micro electrode and a method of manufacture.Type: ApplicationFiled: April 15, 2019Publication date: August 8, 2019Inventor: Jens SCHOUENBORG
-
Patent number: 10363411Abstract: A medical microelectrode includes an elongate electrode body including a tip section, a main body section and, optionally, a coupling section. The tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid. Additionally the microelectrode includes a dissolution retarding layer on the first electrode matrix element and/or a second electrode matrix element disposed between the first electrode matrix element and the electrode. Upon dissolution or biodegradation of the first electrode matrix element a drug comprised by the first electrode matrix element or the second electrode matrix element is released into the tissue. Also disclosed are bundles and arrays of the electrodes and their use.Type: GrantFiled: June 13, 2017Date of Patent: July 30, 2019Assignee: NEURONANO ABInventors: Fredrik Ek, Nils Danielsen, Jenny Eriksson Linsmeier, Per Petersson, Jens Schouenborg
-
Patent number: 10315027Abstract: A proto microelectrode from which a micro electrode is formed in situ upon insertion into soft tissue comprises a flexible oblong electrode body of electrically conducting material having a front end and a rear end. The electrode body having a metal or a metal alloy or an electrically conducting form of carbon or an electrically conducting polymer or a combination thereof. A first coat of a water soluble and/or swellable and/or degradable material is disposed on the electrode body and extends along is at least over a distal portion thereof. A second coat of electrically insulating, water insoluble flexible polymer material is disposed on the first coat. The second coat comprises one or more through openings at or near its front end. Also disclosed is a corresponding micro electrode and a method of manufacture.Type: GrantFiled: June 19, 2013Date of Patent: June 11, 2019Assignee: NEURONANO ABInventor: Jens Schouenborg
-
Publication number: 20190134401Abstract: A method for optimization of a stimulation specificity of implanted electrodes in excitable tissue of a patient; wherein it comprises the step of electrical stimulation of excitable tissue between one or more combinations of electrode pairs in a cluster of electrodes, or electrical stimulation between one or more combinations of electrode pairs in two or more clusters of electrodes, wherein the two electrodes of said electrode pairs do not belong to the same cluster, wherein the electrical stimulation between different combinations of electrode pairs in a cluster of electrodes, or the electrical stimulation between different combinations of electrode pairs in two or more clusters of electrodes, creates a directed electrical field; wherein the effect of the directed electrical field is assessed after each stimulation step by registering information provided from the patient in view of a therapeutic effect, or by assigning each electrode pair a value related to said information provided by the patient; and chooType: ApplicationFiled: December 7, 2016Publication date: May 9, 2019Applicant: NEURONANO ABInventors: Jens SCHOUENBORG, Hjalmar BJARTMARZ
-
Publication number: 20190060518Abstract: A method of providing a channel filled with aqueous gel in soft tissue comprises injecting a biocompatible aqueous gel into the tissue. Also disclosed is a corresponding device, the combination of the device and a guide for its insertion into tissue, and a system comprising the combination and a reservoir filled with aqueous gel comprising means for exerting pressure on the gel.Type: ApplicationFiled: February 23, 2017Publication date: February 28, 2019Inventor: Jens SCHOUENBORG
-
Publication number: 20190030310Abstract: In a method for implantation of a physically stabilized aggregate of living cells or tissue fragment is injected into a channel provided in soft tissue filled with an aqueous gel. Also discloses are methods of stabilizing such aggregates and fragments and of forming such channel in soft tissue as well as means for carrying out the methods.Type: ApplicationFiled: February 23, 2017Publication date: January 31, 2019Inventor: Jens SCHOUENBORG
-
Patent number: 10188854Abstract: A medical microelectrode includes an elongate electrode body including a tip section, a main body section and, optionally, a coupling section. The tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid. Additionally the microelectrode includes a dissolution retarding layer on the first electrode matrix element and/or a second electrode matrix element disposed between the first electrode matrix element and the electrode. Upon dissolution or biodegradation of the first electrode matrix element a drug comprised by the first electrode matrix element or the second electrode matrix element is released into the tissue. Also disclosed are bundles and arrays of the electrodes and their use, which may be positioned on a face of a solid support.Type: GrantFiled: December 8, 2016Date of Patent: January 29, 2019Assignee: NEURONANO ABInventors: Fredrik Ek, Nils Danielsen, Jenny Eriksson Linsmeier, Per Petersson, Jens Schouenborg
-
Publication number: 20180369589Abstract: A method for optimization of the stimulation pattern of a set of implanted electrodes in excitable tissue of a patient is disclosed, wherein it comprises the steps of: (a) choosing a first group of a certain number of from said set of implanted electrodes, (b) stimulating the excitable tissue electrically by said first group of electrodes, (c) registering information provided by the patient, (d) assigning each electrode of said first group of electrodes a value related to said information, wherein these steps are repeated for one or more further groups of said certain number of electrodes chosen from said set of implanted electrodes, wherein each electrode may be included in one or several groups, wherein the total assigned value for each electrode is calculated, and wherein electrodes having a total assigned value exceeding a predetermined value or a predetermined number of the electrodes having the highest total assigned value are chosen to be included in said stimulation pattern, as well as a method for trType: ApplicationFiled: June 3, 2016Publication date: December 27, 2018Applicant: NEURONANO ABInventors: Jens SCHOUENBORG, Hjalmar BJARTMARZ
-
Publication number: 20180369572Abstract: A microelectrode comprises an oblong electrically conducting electrode body covered by distal and proximal sections of a layer of insulating material except for an annular contact section disposed between them, a blunt distal bulge at the distal end of a radial extension substantially greater than that of the proximal section of non-conducting material. For implantation into soft tissue the microelectrode is provided with a support of a material dissolvable in body fluid. Also disclosed is a set of microelectrodes sharing such support, a method of manufacture of the microelectrode and the set, and uses of the microelectrode and the set.Type: ApplicationFiled: November 21, 2016Publication date: December 27, 2018Inventors: Jens SCHOUENBORG, Mohsin MOHAMMED
-
Publication number: 20180193649Abstract: A method for optimization of the stimulation pattern of a set of implanted electrodes in excitable tissue of a patient is disclosed, wherein it comprises the steps of: (a) choosing a first group of a certain number of from said set of implanted electrodes, (b) stimulating the excitable tissue electrically by said first group of electrodes, (c) registering information provided by the patient, (d) assigning each electrode of said first group of electrodes a value related to said information, wherein these steps are repeated for one or more further groups of said certain number of electrodes chosen from said set of implanted electrodes, wherein each electrode may be included in one or several groups, wherein the total assigned value for each electrode is calculated, and wherein electrodes having a total assigned value exceeding a predetermined value or a predetermined number of the electrodes having the highest total assigned value are chosen to be included in said stimulation pattern, as well as a method for trType: ApplicationFiled: July 7, 2016Publication date: July 12, 2018Applicant: NEURONANO ABInventors: Jens SCHOUENBORG, Hjalmar BJARTMARZ
-
Patent number: 9878147Abstract: A medical microelectrode includes an elongate electrode body including a tip section, a main body section and, optionally, a coupling section. The tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid. Additionally the microelectrode includes a dissolution retarding layer on the first electrode matrix element and/or a second electrode matrix element disposed between the first electrode matrix element and the electrode. Upon dissolution or biodegradation of the first electrode matrix element a drug comprised by the first electrode matrix element or the second electrode matrix element is released into the tissue. Also disclosed are bundles and arrays of the electrodes and their use.Type: GrantFiled: February 6, 2015Date of Patent: January 30, 2018Assignee: NEURONANO ABInventors: Fredrik Ek, Nils Danielsen, Jenny Eriksson Linsmeier, Per Petersson, Jens Schouenborg
-
Publication number: 20170274201Abstract: A medical microelectrode includes an elongate electrode body including a tip section, a main body section and, optionally, a coupling section. The tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid. Additionally the microelectrode includes a dissolution retarding layer on the first electrode matrix element and/or a second electrode matrix element disposed between the first electrode matrix element and the electrode. Upon dissolution or biodegradation of the first electrode matrix element a drug comprised by the first electrode matrix element or the second electrode matrix element is released into the tissue. Also disclosed are bundles and arrays of the electrodes and their use.Type: ApplicationFiled: June 13, 2017Publication date: September 28, 2017Inventors: Fredrik EK, Nils DANIELSEN, Jenny ERIKSSON LINSMEIER, Per PETERSSON, Jens SCHOUENBORG
-
Publication number: 20170251976Abstract: A method of providing a channel in nervous tissue filled with an aqueous gel for implantation of a microelectrode or other medical device lacking sufficient physical stability for direct implantation by insertion, comprises providing an apparatus comprising an oblong rigid pin covered by a dry gel forming agent; locating a target in the tissue; defining a straight insertion path a desired tissue insertion point and the target; aligning the pin with its end foremost with the insertion path; inserting the pin into the tissue to a position near or at the target; allowing sufficient time to pass for a gel to be formed around the pin, withdrawing the pin. Also disclosed is a corresponding channel; a method of implantation of a microelectrode or microprobe into nervous tissue via the channel; a corresponding method of implantation of living cells; a corresponding apparatus for forming the channel.Type: ApplicationFiled: August 28, 2015Publication date: September 7, 2017Inventor: Jens SCHOUENBORG
-
Publication number: 20170087352Abstract: A medical microelectrode includes an elongate electrode body including a tip section, a main body section and, optionally, a coupling section. The tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid. Additionally the microelectrode includes a dissolution retarding layer on the first electrode matrix element and/or a second electrode matrix element disposed between the first electrode matrix element and the electrode. Upon dissolution or biodegradation of the first electrode matrix element a drug comprised by the first electrode matrix element or the second electrode matrix element is released into the tissue. Also disclosed are bundles and arrays of the electrodes and their use, which may be positioned on a face of a solid support.Type: ApplicationFiled: December 8, 2016Publication date: March 30, 2017Applicant: NEURONANO ABInventors: Fredrik EK, Nils DANIELSEN, Jenny ERIKSSON LINSMEIER, Per PETERSSON, Jens SCHOUENBORG
-
Publication number: 20170000419Abstract: A device for insertion into soft tissue including a micro electrode, a micro light source; a stiffening element having a material dissolvable or degradable in aqueous body fluid or a material swellable in such fluid to form a transparent gel; a coat of a flexible non-conducting polymer material on the stiffening element; a base disposed at the rear end of the device. The flexible coat has a distal opening allowing light emitted from the light source to leave the device upon said collapse or dissolution or swelling. Also disclosed is a therapeutic or diagnostic device formed in the tissue from the insertable device, uses thereof, and a method of disposing the insertable device in soft tissue.Type: ApplicationFiled: December 18, 2014Publication date: January 5, 2017Inventor: Jens SCHOUENBORG
-
Patent number: 9533140Abstract: A medical microelectrode includes an elongate electrode body including a tip section, a main body section and, optionally, a coupling section. The tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid. Additionally the microelectrode includes a dissolution retarding layer on the first electrode matrix element and/or a second electrode matrix element disposed between the first electrode matrix element and the electrode. Upon dissolution or biodegradation of the first electrode matrix element a drug comprised by the first electrode matrix element or the second electrode matrix element is released into the tissue. Also disclosed are bundles and arrays of the electrodes and their use.Type: GrantFiled: July 11, 2014Date of Patent: January 3, 2017Assignee: NEURONANO ABInventors: Fredrik Ek, Nils Danielsen, Jenny Eriksson Linsmeier, Per Petersson, Jens Schouenborg
-
Publication number: 20150151109Abstract: A medical microelectrode includes an elongate electrode body including a tip section, a main body section and, optionally, a coupling section. The tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid. Additionally the microelectrode includes a dissolution retarding layer on the first electrode matrix element and/or a second electrode matrix element disposed between the first electrode matrix element and the electrode. Upon dissolution or biodegradation of the first electrode matrix element a drug comprised by the first electrode matrix element or the second electrode matrix element is released into the tissue. Also disclosed are bundles and arrays of the electrodes and their use.Type: ApplicationFiled: February 6, 2015Publication date: June 4, 2015Inventors: Fredrik Ek, Nils Danielsen, Jenny Eriksson Linsmeier, Per Petersson, Jens Schouenborg
-
Publication number: 20150151107Abstract: A proto microelectrode from which a micro electrode is formed in situ upon insertion into soft tissue comprises a flexible oblong electrode body of electrically conducting material having a front end and a rear end. The electrode body having a metal or a metal alloy or an electrically conducting form of carbon or an electrically conducting polymer or a combination thereof. A first coat of a water soluble and/or swellable and/or degradable material is disposed on the electrode body and extends along is at least over a distal portion thereof. A second coat of electrically insulating, water insoluble flexible polymer material is disposed on the first coat. The second coat comprises one or more through openings at or near its front end. Also disclosed is a corresponding micro electrode and a method of manufacture.Type: ApplicationFiled: June 19, 2013Publication date: June 4, 2015Applicant: NEURONANO ABInventor: Jens Schouenborg
-
Patent number: 8954142Abstract: A medical microelectrode includes an elongate electrode body including a tip section, a main body section and, optionally, a coupling section. The tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid. Additionally the microelectrode includes a dissolution retarding layer on the first electrode matrix element and/or a second electrode matrix element disposed between the first electrode matrix element and the electrode. Upon dissolution or biodegradation of the first electrode matrix element a drug comprised by the first electrode matrix element or the second electrode matrix element is released into the tissue. Also disclosed are bundles and arrays of the electrodes and their use.Type: GrantFiled: June 3, 2010Date of Patent: February 10, 2015Assignee: Nauronano ABInventors: Fredrik Ek, Nils Danielsen, Jenny Eriksson Linsmeier, Per Petersson, Jens Schouenborg
-
Publication number: 20140323948Abstract: A medical microelectrode includes an elongate electrode body including a tip section, a main body section and, optionally, a coupling section. The tip section, the main body section and, optionally, the coupling section are embedded in a first electrode matrix element, which is substantially rigid, biocompatible and soluble or biodegradable in a body fluid. Additionally the microelectrode includes a dissolution retarding layer on the first electrode matrix element and/or a second electrode matrix element disposed between the first electrode matrix element and the electrode. Upon dissolution or biodegradation of the first electrode matrix element a drug comprised by the first electrode matrix element or the second electrode matrix element is released into the tissue. Also disclosed are bundles and arrays of the electrodes and their use.Type: ApplicationFiled: July 11, 2014Publication date: October 30, 2014Inventors: Fredrik Ek, Nils Danielsen, Jenny Eriksson Linsmeier, Per Petersson, Jens Schouenborg