Patents by Inventor Jens W. Eckstein

Jens W. Eckstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human ubiquitin conjugating enzyme
    Patent number: 5981699
    Abstract: The present invention concerns a novel human ubiquitin-conjugating enzyme which is implicated in the ubiquitin-mediated inactivation of cell-cycle regulatory proteins, partucularly p53. The present invention makes available diagnostic and therapeutic assays and reagents for detecting and treating transformed cells, such as may be useful in the detection of cancer. The present invention also provides reagents for altering the normal regulation cell proliferation in untransformed cells, such as by upregulating certain cell-cycle checkpoints, e.g. to protect normal cells against DNA damaging reagents.
    Type: Grant
    Filed: May 23, 1994
    Date of Patent: November 9, 1999
    Assignee: Mitotix, Inc.
    Inventors: Giulio Draetta, Mark Rolfe, Jens W. Eckstein
  • Ubiquitin conjugating enzymes
    Patent number: 5744343
    Abstract: The present invention concerns three ubiquitin-conjugating enzymes.
    Type: Grant
    Filed: September 13, 1994
    Date of Patent: April 28, 1998
    Assignee: Mitotix, Inc.
    Inventors: Giulio Draetta, Mark Rolfe, Jens W. Eckstein, Guillaume Cottarel