Patents by Inventor Jens Wittenberg

Jens Wittenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BICYCLIC AROMA CHEMICALS
    Publication number: 20240051905
    Abstract: The present invention relates to new bicyclic compounds as aroma chemicals. Specifically, it relates to the use of bicyclic aroma compounds as an aroma chemical and also for enhancing and/or modifying the aroma of a composition.
    Type: Application
    Filed: December 15, 2021
    Publication date: February 15, 2024
    Inventors: Ralf PELZER, Jens WITTENBERG, Wolfgang SIEGEL
  • 2,4-DIETHYLOCTA-2,6-DIENAL AND ITS USE AS AROMA CHEMICAL
    Publication number: 20230024552
    Abstract: The present invention relates to 2,4-diethylocta-2,6-dienal and a method of preparing same, to the use of 2,4-diethylocta-2,6-dienal as aroma chemical; to the use of 2,4-diethylocta-2,6-dienal for preparing an aroma chemical composition or for modifying the aroma character of an aroma chemical composition; to an aroma chemical composition containing 2,4-diethylocta-2,6-dienal; and to a method of preparing an aromatized composition or for modifying the aroma character of an aromatized composition.
    Type: Application
    Filed: December 16, 2020
    Publication date: January 26, 2023
    Inventors: Ralf PELZER, Florian GARLICHS, Silke WEYLAND, Jens WITTENBERG, Wolfgang SIEGEL
  • Use of physiological cooling active ingredients, and compositions comprising such active ingredients
    Patent number: 11434220
    Abstract: The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: September 6, 2022
    Assignees: BASF SE, SYMRISE AG
    Inventors: Benoît Join, Jekaterina Ongouta, Michael Backes, Rahim Brodhage, Arnold Machinek, Hubert Loges, Susanne Mundt, Tom Somers, Thomas Subkowski, Jens Wittenberg, Martin Weisel, Wolfgang Siegel, Claus Bollschweiler, Ralf Pelzer
  • Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof
    Patent number: 11044931
    Abstract: The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.
    Type: Grant
    Filed: July 29, 2019
    Date of Patent: June 29, 2021
    Assignee: BASF SE
    Inventors: Thomas Subkowski, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel, Ralf Pelzer
  • USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS
    Publication number: 20200190052
    Abstract: The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.
    Type: Application
    Filed: August 31, 2018
    Publication date: June 18, 2020
    Inventors: Benoît JOIN, Jekaterina ONGOUTA, Michael BACKES, Rahim BRODHAGE, Arnold MACHINEK, Hubert LOGES, Susanne MUNDT, Tom SOMERS, Thomas SUBKOWSKI, Jens WITTENBERG, Martin WEISEL, Wolfgang SIEGEL, Claus BOLLSCHWEILER, Ralf PELZER
  • Use of physiological cooling active ingredients, and agents containing such active ingredients
    Patent number: 10584134
    Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: March 10, 2020
    Assignees: SYMRISE AG, BASF SE
    Inventors: Thomas Subkowski, Michael Backes, Heiko Oertling, Arnold Machinek, Hubert Loges, Ulrike Simchen, Horst Surburg, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel
  • LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF
    Publication number: 20190350239
    Abstract: The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.
    Type: Application
    Filed: July 29, 2019
    Publication date: November 21, 2019
    Inventors: Thomas SUBKOWSKI, Claus BOLLSCHWEILER, Jens WITTENBERG, Wolfgang SIEGEL, Ralf PELZER
  • Low molecular weight modulators of the cold menthol receptor TRPM8 and use thereof
    Patent number: 10398159
    Abstract: The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: September 3, 2019
    Assignee: BASF SE
    Inventors: Thomas Subkowski, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel, Ralf Pelzer
  • Process for continuously preparing di-C-alkyl succinates
    Patent number: 10047035
    Abstract: The invention relates to a process for continuously preparing di-C1-3-alkyl succinates by reacting succinic acid with an C1-3-alkanol in the presence of a fixed-bed heterogeneous acidic esterification catalyst in a tubular reactor at a temperature in the range of from 60 to 100° C., wherein a mixture, comprising succinic acid, C1-3-alkanol, mono-C1-3-alkyl succinate, di-C1-3-alkyl succinate and water, is formed in a mixing stage and fed to the entrance of the tubular reactor, and wherein 5 to 75% of the outlet flow rate of the tubular reactor are recycled directly to the mixing stage as a recycle stream, and the molar ratio of C1-3-alkanol to succinic acid added to the mixing zone, and not including the C1-3-alkanol and succinic acid at the recycle stream, being in the range of from 2.0 to 9.5.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: August 14, 2018
    Assignee: BASF SE
    Inventors: Stefanie Demming, Suman Thotla, Jens Wittenberg, Gabriele Iffland, Till Christian Brueggemann, Yvonne Hoelzl, Wolfgang Siegel, Stephan Freyer
  • USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS
    Publication number: 20180093997
    Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.
    Type: Application
    Filed: June 21, 2017
    Publication date: April 5, 2018
    Inventors: Thomas Subkowski, Michael Backes, Heiko Oertling, Arnold Machinek, Hubert Loges, Ulrike Simchen, Horst Surburg, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel
  • PROCESS FOR CONTINUOUSLY PREPARING DI-C1-3-ALKYL SUCCINATES
    Publication number: 20170342015
    Abstract: The invention relates to a process for continuously preparing di-C1-3-alkyl succinates by reacting succinic acid with an C1-3-alkanol in the presence of a fixed-bed heterogeneous acidic esterification catalyst in a tubular reactor at a temperature in the range of from 60 to 100° C., wherein a mixture, comprising succinic acid, C1-3-alkanol, mono-C1-3-alkyl succinate, di-C1-3-alkyl succinate and water, is formed in a mixing stage and fed to the entrance of the tubular reactor, and wherein 5 to 75% of the outlet flow rate of the tubular reactor are recycled directly to the mixing stage as a recycle stream, and the molar ratio of C1-3-alkanol to succinic acid added to the mixing zone, and not including the C1-3-alkanol and succinic acid at the recycle stream, being in the range of from 2.0 to 9.5.
    Type: Application
    Filed: July 25, 2017
    Publication date: November 30, 2017
    Applicant: BASF SE
    Inventors: Stefanie Demming, Suman Thotla, Jens Wittenberg, Gabriele Iffland, Till Christian Brueggemann, Yvonne Hoelzl, Wolfgang Siegel, Stephan Freyer
  • LOW MOLECULAR WEIGHT MODULATORS OF THE COLD MENTHOL RECEPTOR TRPM8 AND USE THEREOF
    Publication number: 20170265510
    Abstract: The invention relates to new types of modulators of the cold menthol receptor TRPM8, to methods of modulating the TRPM8 receptor using these modulators; and in particular the use of the modulators for inducing a sensation of coldness; and also the articles and compositions produced using these modulators.
    Type: Application
    Filed: June 1, 2017
    Publication date: September 21, 2017
    Inventors: THOMAS SUBKOWSKI, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel, Ralf Pelzer
  • Process for continuously preparing di-C-alkyl succinates
    Patent number: 9738588
    Abstract: The invention relates to a process for continuously preparing di-C1-3-alkyl succinates by reacting succinic acid with an C1-3-alkanol in the presence of a fixed-bed heterogeneous acidic esterification catalyst in a tubular reactor at a temperature in the range of from 60 to 100° C., wherein a mixture, comprising succinic acid, C1-3-alkanol, mono-C1-3-alkyl succinate, di-C1-3-alkyl succinate and water, is formed in a mixing stage and fed to the entrance of the tubular reactor, and wherein 5 to 75% of the outlet flow rate of the tubular reactor are recycled directly to the mixing stage as a recycle stream, and the molar ratio of C1-3-alkanol to succinic acid added to the mixing zone, and not including the C1-3-alkanol and succinic acid at the recycle stream, being in the range of from 2.0 to 9.5.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: August 22, 2017
    Assignee: BASF SE
    Inventors: Stefanie Demming, Suman Thotla, Jens Wittenberg, Gabriele Iffland, Christian Brueggemann, Yvonne Hoelzl, Wolfgang Siegel, Stephan Freyer
  • Use of physiological cooling active ingredients, and agents containing such active ingredients
    Patent number: 9718839
    Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: August 1, 2017
    Assignees: SYMRISE AG, BASF SE
    Inventors: Thomas Subkowski, Michael Backes, Heiko Oertling, Arnold Machinek, Hubert Loges, Ulrike Simchen, Horst Surburg, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel
  • Detection and use of low molecular-weight modulators of the cold-menthol receptor TRPM8
    Patent number: 9346823
    Abstract: The invention relates to novel modulators of the cold menthol receptor TRPM8, to a method for modulating the TRPM8 receptor using said modulators; to the use of the modulators for induction of cold sensation; and to objects and means produced using said modulators.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: May 24, 2016
    Assignee: BASF SE
    Inventors: Thomas Subkowski, Claus Bollschweiler, Jens Wittenberg, Michael Krohn, Holger Zinke
  • PROCESS FOR CONTINUOUSLY PREPARING DI-C1-3-ALKYL SUCCINATES
    Publication number: 20160083328
    Abstract: The invention relates to a process for continuously preparing di-C1-3-alkyl succinates by reacting succinic acid with an C1-3-alkanol in the presence of a fixed-bed heterogeneous acidic esterification catalyst in a tubular reactor at a temperature in the range of from 60 to 100° C., wherein a mixture, comprising succinic acid, C1-3-alkanol, mono-C1-3-alkyl succinate, di-C1-3-alkyl succinate and water, is formed in a mixing stage and fed to the entrance of the tubular reactor, and wherein 5 to 75% of the outlet flow rate of the tubular reactor are recycled directly to the mixing stage as a recycle stream, and the molar ratio of C1-3-alkanol to succinic acid added to the mixing zone, and not including the C1-3-alkanol and succinic acid at the recycle stream, being in the range of from 2.0 to 9.5.
    Type: Application
    Filed: May 7, 2014
    Publication date: March 24, 2016
    Inventors: Stefanie Demming, Suman Thotla, Jens Wittenberg, Gabriele Iffland, Till Christian Brueggemann, Yvonne Hoelzl, Wolfgang Siegel, Stephan Freyer
  • USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS
    Publication number: 20150086491
    Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.
    Type: Application
    Filed: November 5, 2014
    Publication date: March 26, 2015
    Inventors: Thomas Subkowski, Michael Backes, Heiko Oertling, Arnold Machinek, Hubert Loges, Ulrike Simchen, Horst Surburg, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel
  • Use of physiological cooling active ingredients, and agents containing such active ingredients
    Patent number: 8927605
    Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: January 6, 2015
    Assignees: Symrise AG, BASF SE
    Inventors: Thomas Subkowski, Michael Backes, Heiko Oertling, Arnold Machinek, Hubert Loges, Ulrike Simchen, Horst Surburg, Claus Bollschweiler, Jens Wittenberg, Wolfgang Siegel
  • DETECTION AND USE OF LOW MOLECULAR-WEIGHT MODULATORS OF THE COLD-MENTHOL RECEPTOR TRPM8
    Publication number: 20140194433
    Abstract: The invention relates to novel modulators of the cold menthol receptor TRPM8, to a method for modulating the TRPM8 receptor using said modulators; to the use of the modulators for induction of cold sensation; and to objects and means produced using said modulators.
    Type: Application
    Filed: March 12, 2014
    Publication date: July 10, 2014
    Applicant: BASF SE
    Inventors: Thomas Subkowski, Claus Bollschweiler, Jens Wittenberg, Michael Krohn, Holger Zinke
  • Detection and use of low molecular-weight modulators of the cold-menthol receptor TRPM8
    Patent number: 8710096
    Abstract: The invention relates to novel modulators of the cold menthol receptor TRPM8, to a method for modulating the TRPM8 receptor using said modulators; to the use of the modulators for induction of cold sensation; and to objects and means produced using said modulators.
    Type: Grant
    Filed: August 26, 2009
    Date of Patent: April 29, 2014
    Assignee: BASF SE
    Inventors: Thomas Subkowski, Claus Bollschweiler, Jens Wittenberg, Michael Krohn, Holger Zinke