Patents by Inventor Jeong-Eun Hyeon

Jeong-Eun Hyeon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11459554
    Abstract: The present invention relates to an enzyme complex which the following (i) to (iv) are combined: (i) chimeric beta-agarase formed by a fusion of beta-agarase and the dockerin module of endo-?-1,4-glucanase-B; (ii) chimeric kappa-carrageenase formed by a fusion of kappa-carrageenase and the dockerin module of endo-?-1,4-glucanase-B; (iii) chimeric anhydro-galactosidase formed by a fusion of anhydro-galactosidase and the dockerin module of endo?-1,4-glucanase-B; and (iv) mini cellulose-binding protein A, and to a method of degrading red algal biomass using the same. According to the present invention, an enzymatic degradation process is applied for the production of agar degradation products, deviating from conventional methods that relied on physical and chemical pretreatment processes.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: October 4, 2022
    Assignee: Korea University Research and Business Foundation
    Inventors: Sung Ok Han, Dae-Hee Kang, Jeong-Eun Hyeon
  • Patent number: 11248221
    Abstract: The present disclosure relates to an enzyme complex of arabinose isomerase, agarase and 3,6-anhydro galactosidase and a method for producing tagatose by degrading agar using the same. By using the enzyme complex according to the present disclosure, agar obtained from marine biomass can be degraded effectively and useful physiologically active substances such as tagatose can be obtained effectively therefrom.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: February 15, 2022
    Assignee: Korea University Research and Business Foundation
    Inventors: Sung Ok Han, Da-Woon Jeong, Jeong Eun Hyeon
  • Patent number: 11085034
    Abstract: The present invention relates to an enzyme complex in which a heme polymerase and a heme ligase are linked to each other via the dockerin module of cellulase, and to a method for producing a hemozoin using the same. The enzyme complex according to the present invention can polymerize heme with higher efficiency than conventional enzymes, and thus can more efficiently produce hemozoin, a conductive biopolymer.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: August 10, 2021
    Assignee: Korea University Research and Business Foundation
    Inventors: Sung Ok Han, Jeong-Eun Hyeon, Young-jin Ko
  • Patent number: 11072788
    Abstract: The present invention relates to an expansin-agarase enzyme complex and a method of degrading agar by using the same. The use of the enzyme complex according to the present invention can efficiently degrade agar obtained from marine biomass, and thus can efficiently provide not only galactose or glucose, necessary for ethanol production, but also useful biologically active substances, such as diose, triose, and oligosaccharides.
    Type: Grant
    Filed: January 2, 2018
    Date of Patent: July 27, 2021
    Assignee: Korea University Research and Business Foundation
    Inventors: Sung Ok Han, Da-woon Jeong, Jeong-Eun Hyeon
  • Publication number: 20210009982
    Abstract: The present disclosure relates to an enzyme complex of arabinose isomerase, agarase and 3,6-anhydro galactosidase and a method for producing tagatose by degrading agar using the same. By using the enzyme complex according to the present disclosure, agar obtained from marine biomass can be degraded effectively and useful physiologically active substances such as tagatose can be obtained effectively therefrom.
    Type: Application
    Filed: April 8, 2020
    Publication date: January 14, 2021
    Applicant: Korea University Research and Business Foundation
    Inventors: Sung Ok HAN, Da-Woon JEONG, Jeong Eun HYEON
  • Publication number: 20200291379
    Abstract: The present invention relates to an enzym complex in which a heme polymerase and a heme ligase are linked to each other via the dockerin module of cellulas, and to a method for producing a hemozoin using the same. The enzyme complex according to the present invention can polymerize heme with higher efficiency than conventional enzymes, and thus can more efficiently produce hemozoin, a conductive biopolymer.
    Type: Application
    Filed: December 6, 2017
    Publication date: September 17, 2020
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Sung Ok HAN, Jeong-Eun HYEON, Young-jin KO
  • Publication number: 20200190501
    Abstract: The present invention relates to an expansin-agarase enzyme complex and a method of degrading agar by using the same. The use of the enzyme complex according to the present invention can efficiently degrade agar obtained from marine biomass, and thus can efficiently provide not only galactose or glucose necessary for ethanol production, but also useful biologically active substances, such as diose, triose, and oligosaccharides.
    Type: Application
    Filed: January 2, 2018
    Publication date: June 18, 2020
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Sung Ok HAN, Da-woon JEONG, Jeong-Eun HYEON
  • Patent number: 10676768
    Abstract: The present invention relates to an L-cysteine-producing mutant microorganism having introduced therein genes encoding enzymes which are involved in the L-cysteine metabolic pathway, and more particularly to an L-cysteine-producing mutant microorganism having introduced therein cysE, cysK and cysR, which are genes encoding enzymes which are involved in the L-cysteine metabolic pathway, and to a method of producing L-cysteine using the mutant microorganism. According to the present invention, L-cysteine can be produced with high efficiency as a result of regulating metabolic fluxes associated with the L-cysteine metabolic pathway of the mutant microorganism and regulating a system for supplying a sulfur source essential for synthesis of L-cysteine.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: June 9, 2020
    Assignee: Korea University Research and Business Foundation
    Inventors: Sung Ok Han, Young-Chul Joo, Jeong-Eun Hyeon, Seung-Kyou You
  • Publication number: 20190284591
    Abstract: The present invention relates to an L-cysteine-producing mutant microorganism having introduced therein genes encoding enzymes which are involved in the L-cysteine metabolic pathway, and more particularly to an L-cysteine-producing mutant microorganism having introduced therein cysE, cysK and cysR, which are genes encoding enzymes which are involved in the L-cysteine metabolic pathway, and to a method of producing L-cysteine using the mutant microorganism. According to the present invention, L-cysteine can be produced with high efficiency as a result of regulating metabolic fluxes associated with the L-cysteine metabolic pathway of the mutant microorganism and regulating a system for supplying a sulfur source essential for synthesis of L-cysteine.
    Type: Application
    Filed: December 7, 2016
    Publication date: September 19, 2019
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Sung Ok HAN, Young-Chul JOO, Jeong-Eun HYEON, Seung-Kyou YOU
  • Patent number: 10351885
    Abstract: The present invention relates to a mutant microorganism having the ability to produce 5-aminolevulinic acid, and more particularly, to a mutant microorganism having the ability to produce 5-aminolevulinic acid wherein a glutamyl-tRNA reductase-encoding gene is introduced in a glutamic acid-producing microorganism, and to a method for producing 5-aminolevulinic acid using the same. According to the present invention, 5-aminolevulinic acid that is useful in the medical or agricultural field can be produced in a significantly higher yield than that of conventional production methods.
    Type: Grant
    Filed: July 24, 2016
    Date of Patent: July 16, 2019
    Assignee: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Sung Ok Han, Seung-Kyou You, Jeong-Eun Hyeon, Young-jin Ko
  • Publication number: 20190010475
    Abstract: The present invention relates to an enzyme complex which the following (i) to (iv) are combined: (i) chimeric beta-agarase formed by a fusion of beta-agarase and the dockerin module of endo-?-1,4-glucanase-B; (ii) chimeric kappa-carrageenase formed by a fusion of kappa-carrageenase and the dockerin module of endo-?-1,4-glucanase-B; (iii) chimeric anhydro-galactosidase formed by a fusion of anhydro-galactosidase and the dockerin module of endo-?-1,4-glucanase-B; and (iv) mini cellulose-binding protein A, and to a method of degrading red algal biomass using the same. According to the present invention, an enzymatic degradation process is applied for the production of agar degradation products, deviating from conventional methods that relied on physical and chemical pretreatment processes.
    Type: Application
    Filed: April 1, 2016
    Publication date: January 10, 2019
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Sung Ok HAN, Dae-Hee KANG, Jeong-Eun HYEON
  • Publication number: 20170292134
    Abstract: The present invention relates to a mutant microorganism having the ability to produce 5-aminolevulinic acid, and more particularly, to a mutant microorganism having the ability to produce 5-aminolevulinic acid wherein a glutamyl-tRNA reductase-encoding gene is introduced in a glutamic acid-producing microorganism, and to a method for producing 5-aminolevulinic acid using the same. According to the present invention, 5-aminolevulinic acid that is useful in the medical or agricultural field can be produced in a significantly higher yield than that of conventional production methods.
    Type: Application
    Filed: July 24, 2016
    Publication date: October 12, 2017
    Inventors: Sung Ok Han, Seung-Kyou You, Jeong-Eun Hyeon