Patents by Inventor Jeong Hyeon BAK

Jeong Hyeon BAK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230272026
    Abstract: The present invention relates to a cytokine trimer domain in which a first monomer and a second monomer linked by linker (dimer) and a third monomer are coupled by a knob-into-hole and a novel type of fusion protein in which antibody and cytokine trimer domains are linked (receptor-antibody conjugated (cell) engager, RACE) prepared by replacing a constant region (Fc) of an antibody with the cytokine trimer domain, and RACE according to the present invention exhibits superior binding ability to the target receptor than the parent antibody as well as excellent simultaneous binding ability to the antigen and the target receptor, which can be usefully utilized as a bispecific pharmaceutical composition.
    Type: Application
    Filed: June 22, 2022
    Publication date: August 31, 2023
    Inventors: Kka Bi SON, Jeong Hyeon BAK, Dae Hee LEE, Se Il JANG, Jung Min LEE, Ji Hye YOON, Jong Gwan JEONG