Abstract: The present invention relates to a pharmaceutical composition containing FK506 derivative for treating a fungal infection caused by the genus Cryptococcus or the genus Candida, and a use thereof. In addition, the present invention relates to a therapeutic agent for fungal infection caused by the genus Cryptococcus or the genus Candida, the therapeutic agent containing FK506 derivative. The pharmaceutical composition of the present invention, is harmless to the human body, and can make a great contribution to providing antifungal drugs with an excellent antifungal effect.

Abstract: Disclosed is a method for expecting and diagnosing UQCRB-related disease, and more particularly, related to a method for diagnosing a UQCRB-related disease and a cholesterol biosynthesis related disease, as well as expecting risks of post-occurrence of the UQCRB-related disease and the cholesterol biosynthesis related disease, simply by measuring an expression level of miRNA, and a kit and a biomarker composition for the method.

Abstract: Disclosed are data processing and analysis methods for gene expression data for identifying endogenous reference genes and a composition for the quantitative analysis of gene expression, comprising a pair of primers and/or probes useful in amplifying the identified endogenous reference genes. Introduced with the concepts of “Zero's proportion” and CV, the method allows different datasets to be integrally analyzed, thereby searching for novel reference genes. By the method, 2,087 genes are first found as housekeeping genes which are expressed in most tissues, and the usefulness thereof in the relative quantification of different target genes is determined by analyzing their expression stability. Of the 2,087 genes, 13 genes show higher expression stability with lower expression levels across a wide range of samples than traditional reference genes such as GAPDH and ACTS, and therefore are suitable for the normalization of universal genes having relatively low expression levels.

Abstract: Disclosed is a angiogenesis inhibition determining method using MALDI mass spectrometry, and more particularly, relate to a method for detecting whether small molecules are bound with a target protein and for measuring a binding distribution between the small molecules and the target protein by comparing a result of MALDI mass spectrometry with a result of immunofluorescence of the small molecules, which are used as drugs, for the target protein, and for determining as angiogenesis is inhibited in a portion overlapping with a portion where the drug small molecules are present after the MALDI mass spectrometry in the cell or in the biosample including organelles and a portion where the target protein is present after immunofluorescence, as well as for detecting presence or absence and a distribution state of small molecules used as drugs in a sample by using MALDI mass spectrometry.

Abstract: The present invention relates to a primerless base painting composition for parts of a vehicle comprising a resin component including a non-chlorinated modified polyolefin resin and an acrylic resin; a pigment; additives; and a solvent selected from an aqueous solvent and an oil solvent, a kit comprising the same, painted parts of a vehicle comprising the same, and a method for painting and varnishing parts of a vehicle using the same.

Abstract: A time-dependent information management system and method for a mobile phone that enable the management of time-related information in consideration of a change of time zone are provided. The method includes registering an event planned to occur at a first local time based on a first time zone together with a reference time calculated from the first local time; if the mobile phone enters into a second time zone, selecting the event in accordance with a key input; and setting the event to occur at a second local time calculated from the reference time. The system and method enable selectively adapting, when a mobile phone moves from a first time zone to a second time zone, times of schedules planned in the first time zone to a local time of second time zone, thereby effectively managing the schedules in multiple time zone-crossing environment.

Abstract: Provided is a liquid crystal display, including: a first substrate; a pixel electrode disposed on the first substrate; a second substrate facing the first substrate; a common electrode disposed on the second substrate; and a liquid crystal layer disposed between the first substrate and the second substrate, the liquid crystal layer including a plurality of liquid crystal molecules, in which the common electrode includes a cross-shaped cutout, the cross-shaped cutout overlapping the pixel electrode and dividing the pixel electrode into a plurality of subregions, and the pixel electrode includes a direction controller extend in a direction parallel to a line connecting an intersecting point of the cross-shaped cutout and a pixel corner edge opposing the intersecting point.

Abstract: A composition for an alignment layer includes a polyimide-based compound including a polymerization initiator coupled to a side chain of the polyimide-based compound.

Abstract: A liquid crystal display includes a first substrate, a second substrate disposed opposite to the first substrate; a pixel electrode disposed on the first substrate; a common electrode disposed on the second substrate; and a liquid crystal layer disposed between the first substrate and the second substrate, where a first cutout having a cross shape is defined in the common electrode, a second cutout is defined in the pixel electrode to be adjacent to and along an edge of the pixel electrode, and the pixel electrode has a step structure, a boundary line of which is in a rhombus shape.

Abstract: A curved liquid crystal display (“LCD”) includes a thin film transistor (“TFT”) array substrate, a counter substrate facing the TFT array substrate, a liquid crystal layer including liquid crystal molecules of negative dielectric anisotropy and disposed between the TFT array substrate and the counter substrate, a liquid crystal alignment layer disposed between the liquid crystal layer and the counter substrate, a liquid crystal alignment base layer disposed between the liquid crystal layer and the TFT array substrate, and a liquid crystal alignment stabilization layer including projections spaced apart from each other on the liquid crystal alignment base layer between the liquid crystal layer and the liquid crystal alignment base layer, wherein the projections include reactive mesogen polymers, and one of the liquid crystal alignment layer and the liquid crystal alignment base layer includes the reactive mesogen polymers.

Abstract: The present invention relates to a composition comprising a repressor of mitofusin gene expression, an inhibitor of mitofusin protein activity, or a mixture thereof as an active ingredient for promoting reprogramming a differentiated cell into a pluripotent stem cell, and a use thereof. The composition according to the present invention increases the efficiency of reprogramming as well as reduces the time required for reprogramming to produce pluripotent stem cells. Therefore, the present composition can be beneficially used to develop the production technology of high efficiency pluripotent stem cell and secure a large-scale culture system. Further, the present composition can be beneficially used to maintain pluripotent stem cells and screen the compounds capable of promoting the reprogramming into pluripotent stem cells.

Abstract: A liquid crystal display includes a first substrate, a pixel electrode which is disposed on the first substrate and includes a first subpixel electrode which is disposed at a pixel area and includes a plurality of first branch electrodes, and a second subpixel electrode which is separated from the first subpixel electrode, disposed at an outer edge of the pixel area, encloses the first subpixel electrode and includes a plurality of second branch electrodes, a second substrate facing the first substrate, a common electrode disposed on the second substrate, and a liquid crystal layer disposed between the first substrate and the second substrate, where a first voltage applied to the first subpixel electrode is larger than a second voltage applied to the second subpixel electrode.

Abstract: A seat back suspension assembly for a vehicle, disposed in a seat back frame inside a vehicle seat, may include a main wire including side wires extending in a vertical direction at left and right side thereof; at least one first support wire extending in a horizontal direction between the side wires at both sides thereof to allow both ends thereof to contact the side wires; at least one second support wire disposed to be spaced from the first support wire and extending in a horizontal direction between the side wires at both sides thereof to allow both ends thereof to contact the side wires; and a side guide injection-molded to cover the side wire and end portions of the first and second support wires contacting the side wire.

Abstract: A multiwavelength optical sub-assembly module including a housing to be connected to an optical cable, a plurality of optical filter units coupled to the housing and configured to guide optical signals, a plurality of transceiver units coupled to the housing and configured to receive the optical signals through the optical filter units or transmit the optical signals to the optical filter units, and a substrate coupled to each of the transceiver units. Thus, distortion of an optical signal is suppressed, and the defect rate of a product is allowed to be decreased by evaluating reliability.

Abstract: A display device includes: a substrate; a gate line disposed on the substrate and extending in a first direction; a data line insulated from the gate line and extending in a second direction intersecting the first direction; a pixel electrode disposed in a pixel region defined by the gate line and the data line; a source electrode connected to the data line; a drain electrode spaced apart from the source electrode; and a color filter layer disposed on the data line, the source electrode, and the drain electrode. The color filter layer includes: a first contact hole exposing the drain electrode, and a second contact hole disposed over at least one of the source electrode and the drain electrode. The pixel electrode is disposed on the color filter layer and is connected to the drain electrode through the first contact hole.

Abstract: The present invention relates to a liquid crystal display that can improve an aperture ratio and liquid crystal control ability. A liquid crystal display according to an exemplary embodiment of the present invention includes: a first substrate and a second substrate which face each other; a pixel electrode disposed on the first substrate; a common electrode disposed on the second substrate; and a liquid crystal layer disposed between the first substrate and the second substrate, in which the common electrode has a first cutout having a cross shape, and the pixel electrode includes a first subpixel electrode having a rhombus shape, a second subpixel electrode surrounding the first subpixel electrode, a second cutout disposed close to and along at least one of the edges of the second subpixel electrode, and a third cutout spacing the first subpixel electrode and the second subpixel electrode.

Abstract: A composition for contaminant identification of cosmetics and a container for cosmetics capable of indicating contamination of cosmetics provided with the composition for contaminant identification of cosmetics are provided, wherein the composition for contaminant identification of cosmetics including an aqueous solution dissolving anthocyanin to have absorbance of 0.15 to 1 when employing distilled water as an absorbance control and measuring absorbance in a range of 510 nm to 720 nm; a beef extract; NaCl; lactose; glucose; and agar powder. The composition for contaminant identification of cosmetics is formed with substances harmless to the skin and indicates a degree of contamination of cosmetics.

Abstract: A seat back suspension assembly for a vehicle, disposed in a seat back frame inside a vehicle seat, may include a main wire including side wires extending in a vertical direction at left and right side thereof; at least one first support wire extending in a horizontal direction between the side wires at both sides thereof to allow both ends thereof to contact the side wires; at least one second support wire disposed to be spaced from the first support wire and extending in a horizontal direction between the side wires at both sides thereof to allow both ends thereof to contact the side wires; and a side guide injection-molded to cover the side wire and end portions of the first and second support wires contacting the side wire.

Abstract: An exemplary embodiment of the present invention provides a liquid crystal display including a first insulation substrate. A pixel electrode is disposed on the first insulation substrate. A first alignment layer is disposed on the pixel electrode. A second insulation substrate faces the first insulation substrate. A common electrode is disposed on a surface of the second insulation substrate, which the surface of the second insulation substrate faces the first insulation substrate. A second alignment layer is disposed on a surface of the common electrode, which the surface of the common electrode faces the first insulation substrate. A liquid crystal layer is disposed between the first alignment layer and the second alignment layer. The liquid crystal layer includes liquid crystal molecules. Liquid crystal molecules adjacent to at least one of the first alignment layer and the second alignment layer have a pre-tilt angle.

Abstract: A liquid crystal display according to an exemplary embodiment of the present invention includes a first insulation substrate and a pixel electrode disposed on the first insulation substrate. A first alignment layer is disposed on the pixel electrode. A second insulation substrate faces the first insulation substrate. A common electrode is disposed on a surface of the second insulation substrate facing the first insulation substrate. A second alignment layer is disposed on a surface of the common electrode facing the first insulation substrate. A liquid crystal layer is disposed between the first alignment layer and the second alignment layer. The liquid crystal layer includes liquid crystal molecules. One of the first alignment layer and the second alignment layer has an electron-rich group and the other has an electron-deficient group.