Abstract: A refrigerator that includes a main body, a wall and a storage compartment. The refrigerator further includes a door rotatably coupled to the main body configured to open and close the storage compartment. The door includes an ice-making chamber formed in a front surface of the door. The refrigerator also includes a cooling chamber that includes a cooler is provided inside the wall and configured to generate cooling air. The refrigerator also includes a cooling air duct configured to connect the ice-making chamber and the cooling chamber to supply the cooling air generated by the cooler to the ice-making chamber.

Abstract: The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing.

Abstract: Provided are a method of concentrating protein in grain powder, grain powder including protein that has been concentrated by using the method, and a feed additive including the grain powder including concentrated protein. According to the method of concentrating protein in grain powder, grain powder is treated with enzyme to increase the water-soluble saccharide content in a source, and by inoculating bacteria or yeast and fermentation, the increased water-soluble saccharide is removed, leading to a higher concentration of protein. Thus, the protein content ratio increase effects and the function of grain powder as a protein source are enhanced.

Abstract: The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing.

Abstract: A water pocket with an open top side is filled with water, mounted in a regular position on a supporting frame, and tilts to supply the water stored in the water pocket to an ice making tray, thereby easily supplying a required amount of water to the ice making tray. A refrigerator includes an ice making tray provided to linearly move with rotation when ice of the ice making tray is separated, or includes a holding preventing member which prevents the ice from being caught by a lower ice making tray, thereby improving a forward-and-backward width of an ice maker. It is possible to easily withdraw ice stored in an ice bucket by pushing an ice discharge button in a state in which the ice bucket is not separated.

Abstract: A water pocket with an open top side is filled with water, mounted in a regular position on a supporting frame, and tilts to supply the water stored in the water pocket to an ice making tray, thereby easily supplying a required amount of water to the ice making tray. A refrigerator includes an ice making tray provided to linearly move with rotation when ice of the ice making tray is separated, or includes a holding preventing member which prevents the ice from being caught by a lower ice making tray, thereby improving a forward-and-backward width of an ice maker. It is possible to easily withdraw ice stored in an ice bucket by pushing an ice discharge button in a state in which the ice bucket is not separated.

Abstract: Disclosed herein is a refrigerator configured to delay increase in temperature of a storage compartment by lowering temperature of air that is heated by a defrost heater. A refrigerator includes a defrost heater, a lower cool air duct including a first flow path configured to guide cool air generated by the evaporator to be supplied to the storage compartment and an upper cool air duct disposed in an upper side of the lower cool air duct and provided with a second flow path configured to guide cool air generated by the evaporator to be supplied to the storage compartment. A cool pack in which cold storage material is filled stores cold storage energy from cool air that is delivered to the second flow path to decrease a temperature of air passing via the second flow path, so that increase of an internal temperature of the storage compartment is delayed.

Abstract: The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing.

Abstract: Provided is pyrazole derivatives as a TNIK (Traf2- and NCK-interacting kinase), IKK? (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor; the pyrazole derivative according to the present invention effectively inhibits TNIK, IKK? and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation.

Abstract: Disclosed herein is a refrigerator configured to delay increase in temperature of a storage compartment by lowering temperature of air that is heated by a defrost heater. A refrigerator includes a defrost heater, a lower cool air duct including a first flow path configured to guide cool air generated by the evaporator to be supplied to the storage compartment and an upper cool air duct disposed in an upper side of the lower cool air duct and provided with a second flow path configured to guide cool air generated by the evaporator to be supplied to the storage compartment. A cool pack in which cold storage material is filled stores cold storage energy from cool air that is delivered to the second flow path to decrease a temperature of air passing via the second flow path, so that increase of an internal temperature of the storage compartment is delayed.

Abstract: A display device may include: a plurality of pixels; a gate driver that receives clock signals and generates and applies a plurality of gate signals to a respective plurality of gate lines connected to the plurality of pixels; and a clock signal driver. The clock signal driver may output the clock signals and receive feedback clock signals derived from the clock signals, compare the feedback clock signals, and control amplitudes of the clock signals so that an amplitude difference between the feedback clock signals is less than a threshold.

Abstract: Disclosed is a refrigerator having a first storage chamber, a second storage chamber located below the first storage chamber, an ice maker configured to make ice pieces, an ice bucket configured to store the ice pieces made in the ice maker and a middle wall partitioning inside space of the refrigerator into the first storage chamber and the second storage chamber and including a base portion and a stepped portion located higher than the base portion to form ice-making space, wherein at least one portion of the ice maker and at least one portion of the ice bucket are accommodated in the ice-making space. With this structure, the space for actual use of the first storage chamber can be increased.

Abstract: Provided are 7-azaindole or 4,7-diazaindole derivatives as an IKK? (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor. The 7-azaindole or 4,7-diazaindole derivative effectively inhibits IKK? and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation.

Abstract: Provided are a method of concentrating protein in grain powder, grain powder including protein that has been concentrated by using the method, and a feed additive including the grain powder including concentrated protein. According to the method of concentrating protein in grain powder, grain powder is treated with enzyme to increase the water-soluble saccharide content in a source, and by inoculating bacteria or yeast and fermentation, the increased water-soluble saccharide is removed, leading to a higher concentration of protein. Thus, the protein content ratio increase effects and the function of grain powder as a protein source are enhanced.

Abstract: A refrigerant recovery operation method for use in a refrigerator in which a freezing chamber and a refrigerating chamber are independently cooled is disclosed. The refrigerator and the method for controlling the same provide for performing the refrigerant recovery operation not only when the compressor starts operation but also before the compressor stops operation. The refrigerator increases the refrigerant recovery amount within a predetermined pressure range in which the compressor can operate, and controls the refrigerant recovery operation time according to the outdoor air temperature.

Abstract: A seawater pre-treatment method is provided that includes: installing a filtration filter in the form of a hollow cylinder at a predetermined depth of a sea floor, installing a water collection pipe in which a plurality of openings are formed in the inner part of the filtration filter, the water collection pipe being in fluid communication with a water collection tank, sucking pre-treated water from the inner part of the water collection tank by a water conveying pump, and passing the seawater through the filtration filter by a reverse osmosis method and flowing into the water collection pipe and the water collection tank.

Abstract: There is provided an electrode for a lithium secondary battery. The electrode include a current collector; nanoparticles distributed on a surface of the current collector, each of the nanoparticles including a transition metal or an oxide of the transition metal; and an active material layer disposed on a surface of the current collector having the nanoparticles distributed thereon. This electrode may be employed as a negative electrode for the lithium second battery, to improve a capacity of the lithium second battery.

Abstract: Disclosed herein are a refrigerator includes an ice storage, a transfer member, a transfer motor coupled to the transfer member, and a controller configured to control the transfer motor to rotate the transfer member in a first rotation direction and a second rotation direction, wherein the transfer member prevents the ice cubes stored in the ice storage from agglomerating by rotating in the first rotation direction and the second rotation direction. The controller warns a user of agglomeration of the ice cubes stored in the ice storage in response to no rotation of the transfer motor sensed.

Abstract: A refrigerator includes a body configured to include a storage compartment, a door portion configured to include an inner door pivotably coupled to the body to open/close the storage compartment and an outer door pivotably provided in front of the inner door, an ice making chamber formed at the door portion to be divided from the storage compartment by the inner door and to be opened or closed by the outer door, an ice making system accommodated in the ice making chamber, a dispenser provided at the door portion to provide water and ice, and a water filter mountable at the door portion to purify water supplied from an external water supply source. The ice making chamber is easily accessible by opening only the outer door while the inner door is closed and prevent cold air in the storage compartment from flowing out.

Abstract: A hydrochromic polydiacetylene polymer patch and a method of manufacturing the same are provided. The hydrochromic polymer patch comprises a polymer matrix; and polydiacetylene present in the polymer matrix. The polydiacetylene has an ionic functional group in the repeating unit thereof. The ionic functional group is R?M+ or R+X?. R? is a carboxylate anion, M+ is an alkali metal cation, and R+ is a quaternary ammonium group, and X? is F?, Cl?, Br?, I?, PF6?, BF4?, bis(trifluoromethane)sulfonimide (Tf2N?), trifluoromethanesulfonate (TfO?), SCN?, or CH3COO?.