Abstract: The present invention relates to an intracellular delivery platform including: a first channel through which a fluid comprising cells and delivery materials flows, and a second channel and a third channel which are connected to the first channel at an angle and through which the fluid comprising cells and delivery materials flows, wherein the fluid forms at least one of a collision region and a vortex region of the fluid in at least one of the first channel, the second channel, and the third channel. According to the present invention, material can be effectively delivered into cells by forming a vortex in channels.

Abstract: There is provided a microfluidic system delivering external materials into a cell by cell mechanoporation using inertia, the microfluidic system including a fluidic channel structure through which a solution containing a cell and external materials flows continuously, in which the fluidic channel structure includes a junction between one or more channels, a localized vortex is generated near an interface of the junction, the cell is deformed by the vortex, and transient discontinuities are generated in a cell membrane by the vortex and the external materials are introduced into the cell by solution exchange between the cell and fluid around the cell.