Patents by Inventor Jerel Boyd Lee Vega

Jerel Boyd Lee Vega has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPID FORMULATIONS CONTAINING NUCLEIC ACIDS AND METHODS OF TREATMENT FOR CYSTIC FIBROSIS
    Publication number: 20230159449
    Abstract: Lipid formulations that encapsulate messenger RNA (mRNA) are provided herein. The mRNA can be used to express CFTR protein in vitro or in vivo. The lipid formulations can be administered via inhalation to treat cystic fibrosis.
    Type: Application
    Filed: November 3, 2022
    Publication date: May 25, 2023
    Inventors: Carlos G. PEREZ-GARCIA, Kiyoshi TACHIKAWA, Daiki MATSUDA, Padmanabh CHIVUKULA, Priya Prakash KARMALI, Yanjie BAO, Jerel Boyd Lee VEGA, Rajesh MUKTHAVARAM, Amit SAGI, Yihua PEI
  • NUCLEIC ACIDS AND METHODS OF TREATMENT FOR CYSTIC FIBROSIS
    Publication number: 20220023442
    Abstract: Nucleotides encoding a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein are provided herein. Also describe are mRNA constructs that can be used to express CFTR protein in vitro or in vivo. The mRNA constructs can be formulated in a lipid formulation and administered via inhalation to treat cystic fibrosis.
    Type: Application
    Filed: April 30, 2021
    Publication date: January 27, 2022
    Inventors: Carlos G. Perez-Garcia, Kiyoshi Tachikawa, Daiki Matsuda, Padmanabh Chivukula, Priya Prakash Karmali, Yanjie Bao, Jerel Boyd Lee Vega, Rajesh Mukthavaram, Amit Sagi
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORNITHINE TRANSCARBAMYLASE DEFICIENCY
    Publication number: 20210284974
    Abstract: The present disclosure describes compositions and methods for treating ornithine transcarbamylase (OTC) deficiency. The compositions include a lipid formulation and messenger RNA (mRNA) encoding an OTC enzyme. The lipid formulations can comprise an ionizable cationic lipid in a lipid nanoparticle encapsulating the mRNA.
    Type: Application
    Filed: March 3, 2021
    Publication date: September 16, 2021
    Inventors: Padmanabh Chivukula, Priya Prakash Karmali, Kiyoshi Tachikawa, Suezanne E. Parker, Marciano Rodriguez Sablad, Pattraranee Limphong, Yanjie Bao, Jerel Boyd Lee Vega