Abstract: Provided herein is a method of modulating an APC peptidome comprising identifying an APC or an APC cell population that expresses an HDACi-associated polypeptide and administering an HDACi to the APC. Also provided herein is a method of identifying an HDACi-associated peptide comprising administering an HDACi to an APC, isolating the polypeptide from an APC MHC molecule binding cleft, and identifying the polypeptide.

Abstract: The invention provides a controlled hypergolic approach to using concentrated hydrogen peroxide in combination with certain hydrocarbons such as ethanol, methanol, methane as well as more common fuels such as gasoline, diesel, DME, JP5, JP8 and the like to generate a gas mixture primarily composed of hydrogen and carbon dioxide. Because air is not used as the oxygen source, this novel process does not allow the formation of nitrous oxide (NOx) compounds, thereby avoiding the primary source of nitrogen contamination as well. The process is executed in a constraining system on a micro scale such that the resulting hydrogen supply is self-pressurizing. This enables the incorporation of an “on-demand” hydrogen fuel source for a variable output fuel cell power plant such as those proposed for use in automobiles, marine vessels and stationary power sources. In another embodiment of the present invention hydrogen peroxide is catalytically, or thermally reacted to provide H2O vapor and O2.