Patents by Inventor Jeremy Beauchamp

Jeremy Beauchamp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10947272
    Abstract: The present invention relates to dual-site BACE1 inhibitors, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: March 16, 2021
    Assignees: Hoffmann-La Roche Inc., ROCHE NIMBLEGEN, INC.
    Inventors: Jeremy Beauchamp, Per-Ola Freskgard, Eric A. Kitas, Victor Lyamichev, Jigar Patel
  • Publication number: 20180179252
    Abstract: The present invention relates to dual-site BACE1 inhibitors, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Application
    Filed: July 21, 2016
    Publication date: June 28, 2018
    Inventors: Jeremy BEAUCHAMP, Per-Ola FRESKGARD, Eric A. KITAS, Victor LYAMICHEV, Jigar PATEL
  • Patent number: 9957307
    Abstract: The present invention provides expression vectors for cell-surface expression of polypeptides comprising a transmembrane domain of glycophorin A.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: May 1, 2018
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Jeremy Beauchamp, Anita Dreyer, Hugues Matile
  • Publication number: 20140335097
    Abstract: The present invention provides an expression vector for cell-surface expression of proteins.
    Type: Application
    Filed: July 31, 2014
    Publication date: November 13, 2014
    Inventors: Jeremy BEAUCHAMP, Anita DREYER, Hugues MATILE
  • Publication number: 20140221360
    Abstract: This invention relates to compounds of formula I, wherein R1 to R3 are as defined herein, as well as pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods for using such compounds for the treatment or prevention of diabetes, particularly type 2 diabetes.
    Type: Application
    Filed: April 4, 2014
    Publication date: August 7, 2014
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jeremy Beauchamp, Agnes Benardeau, Hans Hilpert, Cristiano Migliorini, William Riboulet, Haiyan Wang
  • Publication number: 20130115219
    Abstract: The present invention provides an expression vector for cell-surface expression of proteins.
    Type: Application
    Filed: February 28, 2011
    Publication date: May 9, 2013
    Applicant: F. Hoffmann-La Roche AG
    Inventors: Jeremy Beauchamp, Anita Dreyer, Hugues Matile
  • Publication number: 20110229922
    Abstract: The present invention relates to screening assays for the identification of BACE2 inhibitors.
    Type: Application
    Filed: November 26, 2009
    Publication date: September 22, 2011
    Inventors: Jeremy Beauchamp, Heinz Doebeli, Hugues Matile, Cristiano Migliorini, Michael Prummer, Paolo Salvioni, Haiyan Wang
  • Publication number: 20110065695
    Abstract: This invention relates to compounds of formula I, wherein R1 to R3 are as defined herein, as well as pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods for using such compounds for the treatment or prevention of diabetes, particularly type 2 diabetes.
    Type: Application
    Filed: September 2, 2010
    Publication date: March 17, 2011
    Inventors: Jeremy Beauchamp, Agnès Bénardeau, Hans Hilpert, Cristiano Mighliorini, William Riboulet, Haiyan Wang
  • Publication number: 20070016970
    Abstract: The present invention relates to the sequence of guinea pig chymase. Since guinea pigs express only one chymase isoform, they are particularly suitable as a model for a method for identifying compounds that modulate chymase.
    Type: Application
    Filed: July 11, 2006
    Publication date: January 18, 2007
    Inventors: Juergen Fingerle, Jeremy Beauchamp