Patents by Inventor Jeremy Dahl
Jeremy Dahl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240024503Abstract: Methods and compositions for the production of phospholipid-ligand bioconjugates and uniform targeted microbubbles are provided. These methods and compositions find use in ultrasound and molecular imaging applications related to cancer and other diseases. The methods of the present disclosure comprise contacting a phospholipid comprising a maleimide containing functional group with a ligand comprising a C terminal cysteine residue. The methods disclosed herein solves the problems in producing ready-to-use and clinically translatable ultrasound molecular imaging agents by incorporating small protein ligands engineered to bind against biomarkers representing pathological angiogenesis or abnormal cells. The methods also overcome the current limitations in producing uniformly targeted microbubbles in a scalable, economical and reproducible manner.Type: ApplicationFiled: July 13, 2023Publication date: January 25, 2024Inventors: Rakesh Bam, Jeremy Dahl
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Publication number: 20220331611Abstract: Methods of using pulsed focused ultrasound (pFUS) therapy to treat pancreatic disorders such as type 1 diabetes, pancreatitis, and pancreatic cancer are provided. The methods utilize pulsed focused ultrasound (pFUS) therapy either by itself or in combination with islet transplantation and/or stem cell therapy to promote regeneration of damaged pancreatic tissue, increase insulin secretion in response to glucose, or improve engraftment and revascularization of transplanted islets or beta cells. Additionally, methods of using pFUS are provided for modulating paracrine secretion in the pancreas, islets, beta cells, or stem cells, or at a transplantation site to therapeutically alter levels of various factors including, without limitation, cytokines, growth factors, angiogenic factors, and cell adhesion molecules.Type: ApplicationFiled: April 9, 2020Publication date: October 20, 2022Inventors: Mehdi RAZAVI, Jeremy DAHL, Avnesh S. THAKOR
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Publication number: 20160084948Abstract: Methods, systems and computer program products for imaging fluid in a sample include acquiring a plurality of echo signals for a region of interest in the sample from a plurality of ultrasound transducer elements in an ultrasound transducer array; applying a stationary echo cancellation to the plurality of echo signals to reduce or remove echo signals that are associated with stationary and/or slower moving features to provide a corresponding plurality of filtered signals; extracting coherence information from the plurality of filtered signals; and imaging the region of interest in response to the coherence information from the plurality of filtered signals.Type: ApplicationFiled: May 28, 2014Publication date: March 24, 2016Inventors: Jeremy Dahl, Gregg E. Trahey
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Publication number: 20130336873Abstract: Methods of growing diamond and resulting diamond nanoparticles and diamond films are described herein. An example of a method of growing diamond includes: (1) anchoring diamondoids to a substrate via chemical bonding between the diamondoids and the substrate; (2) forming a protective layer over the diamondoids; and (3) performing chemical vapor deposition using a carbon source to induce diamond growth over the protective layer and the diamondoids.Type: ApplicationFiled: March 15, 2013Publication date: December 19, 2013Inventors: Hitoshi Ishiwata, Zhi-Xun Shen, Nicholas A. Melosh, Jeremy Dahl
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Publication number: 20080094723Abstract: Novel optical devices based on diamondoid-containing materials are disclosed. Materials that may be fabricated from diamondoids included diamondoid nucleated CVD films, diamondoid-containing CVD films, molecular crystals, and polymerized materials. Devices that may be fabricated from the diamondoid-containing materials disclosed herein include solid state dye lasers, semiconductor lasers, light emitting diodes, photodetectors, photoresistors, phototransistors, photovoltaic cells, solar cells, anti-reflection coatings, lenses, mirrors, pressure windows, optical waveguides, and particle and radiation detectors.Type: ApplicationFiled: December 22, 2006Publication date: April 24, 2008Applicant: Chevron U.S.A. Inc.Inventors: Jeremy Dahl, Robert Carlson, Shenggao Liu
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Publication number: 20080094724Abstract: Novel optical devices based on diamondoid-containing materials are disclosed. Materials that may be fabricated from diamondoids included diamondoid nucleated CVD films, diamondoid-containing CVD films, molecular crystals, and polymerized materials. Devices that may be fabricated from the diamondoid-containing materials disclosed herein include solid state dye lasers, semiconductor lasers, light emitting diodes, photodetectors, photoresistors, phototransistors, photovoltaic cells, solar cells, anti-reflection coatings, lenses, mirrors, pressure windows, optical waveguides, and particle and radiation detectors.Type: ApplicationFiled: December 22, 2006Publication date: April 24, 2008Applicant: Chevron U.S.A. Inc.Inventors: Jeremy Dahl, Robert Carlson, Shenggao Liu
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Publication number: 20080094722Abstract: Novel optical devices based on diamondoid-containing materials are disclosed. Materials that may be fabricated from diamondoids included diamondoid nucleated CVD films, diamondoid-containing CVD films, molecular crystals, and polymerized materials. Devices that may be fabricated from the diamondoid-containing materials disclosed herein include solid state dye lasers, semiconductor lasers, light emitting diodes, photodetectors, photoresistors, phototransistors, photovoltaic cells, solar cells, anti-reflection coatings, lenses, mirrors, pressure windows, optical waveguides, and particle and radiation detectors.Type: ApplicationFiled: December 22, 2006Publication date: April 24, 2008Applicant: Chevron U.S.A. Inc.Inventors: Jeremy Dahl, Robert Carlson, Shenggao Liu
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Publication number: 20080009546Abstract: This invention relates to diamondoid derivatives which exhibit therapeutic activity. Specifically, the diamondoid derivatives herein exhibit therapeutic effects in the treatment of neurologic disorders. Also provided are methods of treatment, prevention and inhibition of neurologic disorders in a subject in need.Type: ApplicationFiled: April 17, 2007Publication date: January 10, 2008Applicant: Chevron U.S.A. Inc.Inventors: Shenggao Liu, Frederick Lam, Steve Sciamanna, Robert Carlson, Jeremy Dahl
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Publication number: 20070251446Abstract: Provided is a novel method for nucleating the growth of a diamond film. The method comprises providing a substrate having a diamondoid chemically attached to it, which serves as a superior nucleation site, and then facilitating the growth of the diamond film.Type: ApplicationFiled: March 20, 2007Publication date: November 1, 2007Applicant: Chevron U.S.A. Inc.Inventors: Jeremy Dahl, Robert Carlson, Wasiq Bokhari, Shenggao Liu
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Publication number: 20060258748Abstract: This invention relates to diamondoid derivatives which exhibit therapeutic activity. Specifically, the diamondoid derivatives herein exhibit therapeutic effects in the treatment of neurologic disorders. Also provided are methods of treatment, prevention and inhibition of neurologic disorders in a subject in need.Type: ApplicationFiled: May 8, 2006Publication date: November 16, 2006Applicant: Chevron U.S.A. Inc.Inventors: Shenggao Liu, Frederick Lam, Steve Sciamanna, Robert Carlson, Jeremy Dahl
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Publication number: 20060228479Abstract: Diamonds are used to nucleate diamond and diamond-like carbon films in a chemical vapor deposition process using bias enhancement. A negative bias is applied to the substrate, such that a cationic form of the diamond is accelerated toward the substrate during the nucleation phase of the deposition. In this manner, the diamondoid may be embedded or partially embedded in the substrate and/or growing film, increasing the adhesion of the film to the substrate. According to the present embodiments, it is not necessary to mechanically pre-seed the substrate for nucleation purposes.Type: ApplicationFiled: March 23, 2006Publication date: October 12, 2006Applicant: Chevron U.S.A. Inc.Inventors: Jeremy Dahl, Robert Carlson, Shenggao Liu, Waqar Queshi, Wasiq Bokhari
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Publication number: 20060183870Abstract: This invention is related to heteroatom containing diamondoids (i.e., “heterodiamondoids”) which are compounds having a diamondoid nucleus in which one or more of the diamondoid nucleus carbons has been substitutionally replaced with a noncarbon atom. These heteroatom substituents impart desirable properties to the diamondoid. In addition, the heterodiamondoids are functionalized affording compounds carrying one or more functional groups covalently pendant therefrom. This invention is further related to polymerizable functionalized heterodiamondoids. In a preferred aspect of this invention the diamondoid nuclei are triamantane and higher diamondoid nuclei. In another preferred aspect, the heteroatoms are selected to give rise to diamondoid materials which can serve as n- and p-type materials in electronic devices can serve as optically active materials.Type: ApplicationFiled: January 18, 2006Publication date: August 17, 2006Inventors: Shenggao Liu, Robert Carlson, Jeremy Dahl
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Publication number: 20060063107Abstract: Novel positive-working photoresist compositions are disclosed. The monomers of the base resin of the resist contain diamondoid-containing pendant groups higher than adamantane in the polymantane series; for example, diamantane, triamantane, tetramantane, pentamantane, hexamantane, etc. The diamondoid-containing pendant group may have hydrophilic-enhancing substituents such as a hydroxyl group, and may contain a lactone group. Advantages of the present compositions include enhanced resolution, sensitivity, and adhesion to the substrate.Type: ApplicationFiled: November 4, 2005Publication date: March 23, 2006Applicant: Chevron U.S.A. Inc.Inventors: Shenggao Liu, Jeremy Dahl, Robert Carlson
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Publication number: 20060057496Abstract: Novel positive-working photoresist compositions are disclosed. The monomers of the base resin of the resist contain diamondoid-containing pendant groups higher than adamantane in the polymantane series; for example, diamantane, triamantane, tetramantane, pentamantane, hexamantane, etc. The diamondoid-containing pendant group may have hydrophilic-enhancing substituents such as a hydroxyl group, and may contain a lactone group. Advantages of the present compositions include enhanced resolution, sensitivity, and adhesion to the substrate.Type: ApplicationFiled: November 4, 2005Publication date: March 16, 2006Applicant: Chevron U.S.A. Inc.Inventors: Shenggao Liu, Jeremy Dahl, Robert Carlson
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Publication number: 20050209490Abstract: Novel compounds having a hybrid cubic/hexagonal diamond crystal structure are disclosed. Each of the four compounds have the stoichiometric formula C26H32 and a molecular weight of 344. The four compounds are contemplated to have a utility in diamond film nucleation.Type: ApplicationFiled: December 8, 2004Publication date: September 22, 2005Applicant: Chevron U.S.A. Inc.Inventors: Jeremy Dahl, Robert Carlson, Shenggao Liu
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Publication number: 20050168122Abstract: Novel heterodiamondoid-containing field emission devices (FED's) are disclosed herein. In one embodiment of the present invention, the heteroatom of the heterodiamondoid comprises an electron-donating species (such as nitrogen) as part of the cathode or electron-emitting component of the field emission device.Type: ApplicationFiled: January 4, 2005Publication date: August 4, 2005Applicant: Chevron U.S.A. Inc.Inventors: Jeremy Dahl, Robert Carlson, Shenggao Liu
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Publication number: 20050159634Abstract: Higher diamondoid derivatives capable of taking part in polymerization reactions are disclosed as well as intermediates to these derivatives, polymers formed from these derivatives and methods for preparing the polymers.Type: ApplicationFiled: December 17, 2004Publication date: July 21, 2005Applicant: Chevron U.S.A. Inc.Inventors: Jeremy Dahl, Robert Carlson, Shenggao Liu
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Publication number: 20050074690Abstract: Novel positive-working photoresist compositions are disclosed. The monomers of the base resin of the resist contain diamondoid-containing pendant groups higher than adamantane in the polymantane series; for example, diamantane, triamantane, tetramantane, pentamantane, hexamantane, etc. The diamondoid-containing pendant group may have hydrophilic-enhancing substituents such as a hydroxyl group, and may contain a lactone group. Advantages of the present compositions include enhanced resolution, sensitivity, and adhesion to the substrate.Type: ApplicationFiled: January 23, 2004Publication date: April 7, 2005Inventors: Shenggao Liu, Jeremy Dahl, Robert Carlson
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Publication number: 20050019576Abstract: Novel uses of higher diamondoids are disclosed. Specifically, higher diamondoids may be used to nucleate diamond films and diamond-like carbon films. Such higher diamondoids include iso-tetramantane [1(2)3], anti-tetramantane [121], the two enantiomers of skew-tetramantane [123], the ten possible pentamantane, the thirty nine possible hexamantanes, the one hundred sixty heptamantanes, as well as the various octamantanes, nonamantanes, decamantanes, and undecamantanes.Type: ApplicationFiled: June 10, 2004Publication date: January 27, 2005Applicant: Chevron U.S.A. Inc.Inventors: Jeremy Dahl, Robert Carlson, Shenggao Liu
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Publication number: 20050019955Abstract: Novel biological labels are disclosed herein. The label comprises a functionalized heterodiamondoid functioning as a biological probe, the probe having an affinity for a target analyte molecule. Upon absorption of incident excitation radiation, color center(s) located within the heterodiamondoid are caused to luminesce. The photoemitted light may be detected and analyzed to yield information about the analyte. The color centers in the heterodiamondoid will typically comprise nitrogen-vacancy and/or nitrogen-pore complexes, but may also comprise a dopant impurity atom such as a rare earth or transition metal element.Type: ApplicationFiled: January 15, 2004Publication date: January 27, 2005Inventors: Jeremy Dahl, Robert Carlson, Shenggao Liu, Wasiq Bokhari