Abstract: Ophthalmic devices and ophthalmic systems including alignment sidewalls and blend zones disposed therethrough are described. An example ophthalmic device may include a first and a second optical element having alignment sidewalls shaped to cooperatively couple. The alignment sidewall may include blend zones disposed in the sidewall shaped to transition the sidewall from a ridge to a surface of an optic zone of the optical element. The alignment sidewalls may define a cavity disposed between two coupled optical elements when the alignment sidewalls are cooperatively coupled into which a liquid crystal may be disposed. A method of assembling an ophthalmic device is described. An example method may include aligning a blend zone of a first optical element with a mating blend zone of a second optical element. The example method may further include cooperatively coupling alignment sidewalls of the first optical element and the second optical element.

Abstract: Techniques and mechanisms for the wireless transmission of power or control signals between two components of an implantable ophthalmic system are disclosed herein. An example device includes an accommodating intraocular lens (aIOL) and separate auxiliary electronics, both enclosed in biocompatible materials. The aIOL includes a dynamic optic, control logic, a battery and an antenna. The auxiliary electronics include an antenna, an energy storage cell, and a sensor. The auxiliary electronics may be wirelessly coupled to the aIOL for the wireless transmission of power or control signals.

Abstract: A transceiver for interfacing with an analyte sensor. The transceiver may include an interface device and a notification device. The interface device may be configured to convey a power signal to the analyte sensor and to receive data signals from the analyte sensor. The notification device may be configured to generate one or more of a vibrational, aural, and visual signal based on one or more data signals received from the analyte sensor. The interface device of the transceiver may receive analyte data from the analyte sensor, and the transceiver may comprise a processor configured to calculate an analyte concentration value based on the received analyte data. The notification device may be configured to generate one or more of aural, visual, or vibrational alarm when the calculated analyte concentration value exceeds or falls below a threshold value.

Abstract: A transceiver for interfacing with an analyte sensor. The transceiver may include an interface device and a notification device. The interface device may be configured to convey a power signal to the analyte sensor and to receive data signals from the analyte sensor. The notification device may be configured to generate one or more of a vibrational, aural, and visual signal based on one or more data signals received from the analyte sensor. The interface device of the transceiver may receive analyte data from the analyte sensor, and the transceiver may comprise a processor configured to calculate an analyte concentration value based on the received analyte data. The notification device may be configured to generate one or more of aural, visual, or vibrational alarm when the calculated analyte concentration value exceeds or falls below a threshold value.

Abstract: A transceiver for interfacing with an analyte sensor. The transceiver may include an interface device and a notification device. The interface device may be configured to convey a power signal to the analyte sensor and to receive data signals from the analyte sensor. The notification device may be configured to generate one or more of a vibrational, aural, and visual signal based on one or more data signals received from the analyte sensor. The interface device of the transceiver may receive analyte data from the analyte sensor, and the transceiver may comprise a processor configured to calculate an analyte concentration value based on the received analyte data. The notification device may be configured to generate one or more of aural, visual, or vibrational alarm when the calculated analyte concentration value exceeds or falls below a threshold value.

Abstract: A transceiver for interfacing with an analyte sensor. The transceiver may include an interface device and a notification device. The interface device may be configured to convey a power signal to the analyte sensor and to receive data signals from the analyte sensor. The notification device may be configured to generate one or more of a vibrational, aural, and visual signal based on one or more data signals received from the analyte sensor. The interface device of the transceiver may receive analyte data from the analyte sensor, and the transceiver may comprise a processor configured to calculate an analyte concentration value based on the received analyte data. The notification device may be configured to generate one or more of aural, visual, or vibrational alarm when the calculated analyte concentration value exceeds or falls below a threshold value.

Abstract: A sensor that may be used to detect the presence, amount, and/or concentration of an analyte in a medium within an animal. The sensor may include a sensor housing, an indicator element embedded within and/or covering at least a portion of the sensor housing, and a membrane over the indicator element. The sensor may include one or more of a first coating on an inner surface of the membrane, a second coating on an outer surface of the membrane, and a layer on the outside of the indicator element. One or more of the first coating, second coating, and layer may reduce deterioration of the indicator element by catalyzing degradation of reactive oxygen species (ROS). The one or more coatings on the membrane may increase the light blocking capability of the membrane, which may improve the accuracy of the sensor.

Abstract: Systems and methods for monitoring medication adherence and compliance are provided. A medication monitoring system may include a medication container, a cover, and a beacon system. The beacon system may include a beacon that transmits a wireless signal when the cover is removed from the medication container. A method for monitoring medication adherence and compliance may include detecting when a cover of a medication container is removed from the medication container. The method may further include transmitting based on the detection, a signal from a beacon to a remote device, which indicates the opening of the medication container.

Abstract: An eye-mountable device is provided that includes electronics encapsulated within a rigid, gas-permeable polymeric material. The eye-mountable device includes an electroactive lens that can be operated to control an overall optical power of the eye-mountable device to restore an amount of visual accommodation of an eye to which the device is mounted. A method for fabricating the eye-mountable device is provided that includes applying an adhesive to secure lenses of the electroactive lens together and to maintain an amount of liquid crystal in the space between the lenses. The rigid, gas-permeable polymeric material can then be formed around the electroactive lens, electronics, or other elements of the eye-mountable device. The rigid, gas-permeable polymeric material can be mountable to a corneal surface of an eye or can be disposed on or within a soft polymeric material that is mountable to the corneal surface of the eye.

Abstract: A system including a sensor and a transceiver and configured to determine a concentration of an analyte in a medium of a living animal. The sensor may include first and second signal photodetectors and first and second reference photodetectors, which may each be covered by an associate filter. The first photodetector may receive light emitted from first and second grafts, respectively. The grafts may receive excitation light from one or more light sources. The transceiver may receive signals from the photodetectors of the sensor and may determine the analyte concentration based on the received signals.

Abstract: Techniques and mechanisms for the wireless transmission of power or control signals between two components of an implantable ophthalmic system are disclosed herein. An example device includes an accommodating intraocular lens (aIOL) and separate auxiliary electronics, both enclosed in biocompatible materials. The aIOL includes a dynamic optic, control logic, a battery and an antenna. The auxiliary electronics include an antenna, an energy storage cell, and a sensor. The auxiliary electronics may be wirelessly coupled to the aIOL for the wireless transmission of power or control signals.

Abstract: Techniques and mechanisms for the wireless transmission of power and sensor information between two components of an implantable ophthalmic device are disclosed herein. An example device includes an accommodating intraocular lens (aIOL) and separate auxiliary electronics, both enclosed in biocompatible materials. The aIOL includes a dynamic optic, control logic, a battery and an antenna. The auxiliary electronics include an antenna, an energy storage cell, and a sensor. The auxiliary electronics may be wirelessly coupled to the aIOL for the wireless transmission of power and sensor information.

Abstract: An eye-mountable device is provided that includes electronics encapsulated within a rigid, gas-permeable polymeric material. The eye-mountable device includes an electroactive lens that can be operated to control an overall optical power of the eye-mountable device to restore an amount of visual accommodation of an eye to which the device is mounted. A method for fabricating the eye-mountable device is provided that includes applying an adhesive to secure lenses of the electroactive lens together and to maintain an amount of liquid crystal in the space between the lenses. The rigid, gas-permeable polymeric material can then be formed around the electroactive lens, electronics, or other elements of the eye-mountable device. The rigid, gas-permeable polymeric material can be mountable to a corneal surface of an eye or can be disposed on or within a soft polymeric material that is mountable to the corneal surface of the eye.

Abstract: An eye-mountable device is provided that includes electronics encapsulated within a rigid, gas-permeable polymeric material. The eye-mountable device includes an electroactive lens that can be operated to control an overall optical power of the eye-mountable device to restore an amount of visual accommodation of an eye to which the device is mounted. A method for fabricating the eye-mountable device is provided that includes applying an adhesive to secure lenses of the electroactive lens together and to maintain an amount of liquid crystal in the space between the lenses. The rigid, gas-permeable polymeric material can then be formed around the electroactive lens, electronics, or other elements of the eye-mountable device. The rigid, gas-permeable polymeric material can be mountable to a corneal surface of an eye or can be disposed on or within a soft polymeric material that is mountable to the corneal surface of the eye.

Abstract: Ophthalmic devices and ophthalmic systems including alignment sidewalls and blend zones disposed therethrough are described. An example ophthalmic device may include a first and a second optical element having alignment sidewalls shaped to cooperatively couple. The alignment sidewall may include blend zones disposed in the sidewall shaped to transition the sidewall from a ridge to a surface of an optic zone of the optical element. The alignment sidewalls may define a cavity disposed between two coupled optical elements when the alignment sidewalls are cooperatively coupled into which a liquid crystal may be disposed. A method of assembling an ophthalmic device is described. An example method may include aligning a blend zone of a first optical element with a mating blend zone of a second optical element. The example method may further include cooperatively coupling alignment sidewalls of the first optical element and the second optical element.

Abstract: Methods, sensors, and systems that prevent or reduce data loss when more than one external sensor transceiver is used with a sensor. A sensor may receive a transceiver identification (ID) of an external transceiver conveyed from the external transceiver and determine whether the received transceiver ID is a new transceiver ID. If sensor determines the received transceiver ID to be a new transceiver ID, the sensor may store the received transceiver ID in a nonvolatile storage medium of the sensor and convey, using the sensor, measurement information stored in the nonvolatile storage medium to the external transceiver.

Abstract: Methods, sensors, and systems that prevent or reduce data loss when more than one external sensor transceiver is used with a sensor. A sensor may receive a transceiver identification (ID) of an external transceiver conveyed from the external transceiver and determine whether the received transceiver ID is a new transceiver ID. If sensor determines the received transceiver ID to be a new transceiver ID, the sensor may store the received transceiver ID in a nonvolatile storage medium of the sensor and convey, using the sensor, measurement information stored in the nonvolatile storage medium to the external transceiver.

Abstract: An analyte indicator may include a porous base and may be included in an analyte sensor. The analyte indicator may retain its physical, chemical, and optical properties in the presence of compression. The porous base may not vary in opacity. The analyte indicator may include (i) a polymer unit attached or polymerized onto or out of the porous base and (ii) an analyte sensing element attached to the polymer unit or copolymerized with the polymer unit. The analyte sensing element may include one or more indicator molecule. The analyte sensing element may include one or more indicator polymer chains. The analyte indicator may include (i) an indicator polymer chain attached or polymerized onto or out of the porous base and (ii) indicator molecules attached to the indicator polymer chain.

Abstract: Systems and methods for monitoring medication adherence and compliance are provided. A medication monitoring system may include a medication container, a cover, and a beacon system. The beacon system may include a beacon that transmits a wireless signal when the cover is removed from the medication container. A method for monitoring medication adherence and compliance may include detecting when a cover of a medication container is removed from the medication container.

Abstract: Systems and methods for monitoring medication adherence and compliance are provided. A medication monitoring system may include a medication container, a cover, and a beacon system. The beacon system may include a beacon that transmits a wireless signal when the cover is removed from the medication container. A method for monitoring medication adherence and compliance may include detecting when a cover of a medication container is removed from the medication container. The method may further include transmitting based on the detection, a signal from a beacon to a remote device, which indicates the opening of the medication container.