Abstract: In one embodiment, a method includes receiving, by a WebAuthn proxy, login prompt information from a browser. The WebAuthn proxy and the browser are installed on a device. The method also includes generating, by the WebAuthn proxy, a WebAuthn credential request based on the login prompt information and communicating, by the WebAuthn proxy, the WebAuthn credential request to a WebAuthn authenticator. The method further includes receiving, by the WebAuthn proxy, a WebAuthn response from the WebAuthn authenticator and communicating, by the WebAuthn proxy, the WebAuthn response to the browser.

Abstract: Systems and methods for managing multi-objective alignments in imprinting (e.g., single-sided or double-sided) are provided. An example system includes rollers for moving a template roll, a stage for holding a substrate, a dispenser for dispensing resist on the substrate, a light source for curing the resist to form an imprint on the substrate when a template of the template roll is pressed into the resist on the substrate, a first inspection system for registering a fiducial mark of the template to determine a template offset, a second inspection system for registering the imprint on the substrate to determine a wafer registration offset between a target location and an actual location of the imprint, and a controller for controlling to move the substrate with the resist below the template based on the template offset, and determine an overlay bias of the imprint on the substrate based on the wafer registration offset.

Abstract: In one embodiment, a method includes establishing, by an identity agent installed on a device, a connection to a browser installed on the device and generating, by the identity agent, first device information, a public key, and a private key. The method also includes communicating, by the identity agent, the first device information and the public key to an authentication service and receiving, by the identity agent, a unique identifier from the authentication service. The method further includes generating, by the identity agent, a first signature of the first device information and communicating, by the identity agent, the first signature, the first device information, and the unique identifier to the browser.

Abstract: Described herein are compounds and methods for the treatment of coronavirus infection. The compounds can function as an inhibitor of the main protease (Mpro) of coronaviruses. The compounds can include diphenylmethyl piperazine derivatives, diphenylmethyl piperidine derivatives, diphenylmethylidene piperidine derivatives, tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen derivatives, tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen derivatives, 6,11-dihydrobenzo[c][1]benzoxepin derivatives, 6,11-dihydrobenzo[c][1]benzothiepin derivatives, 5,5-dioxo-6,11-dihydrobenzo[c][1]benzothiepin derivatives, and 6-oxo-5,11-dihydrobenzo[c][1]benzazepin derivatives, as well as pharmaceutically acceptable salts, hydrates, and prodrugs thereof.

Abstract: Systems and methods for managing multi-objective alignments in imprinting (e.g., single-sided or double-sided) are provided. An example system includes rollers for moving a template roll, a stage for holding a substrate, a dispenser for dispensing resist on the substrate, a light source for curing the resist to form an imprint on the substrate when a template of the template roll is pressed into the resist on the substrate, a first inspection system for registering a fiducial mark of the template to determine a template offset, a second inspection system for registering the imprint on the substrate to determine a wafer registration offset between a target location and an actual location of the imprint, and a controller for controlling to move the substrate with the resist below the template based on the template offset, and determine an overlay bias of the imprint on the substrate based on the wafer registration offset.

Abstract: An umbrella valve includes a wall structure having an aperture and a passage adjacent to the aperture. A core member includes a body portion with a shoulder and a retention clip extending from the body portion and including a pair of flexible legs supporting a respective one of a pair of retention flanges spaced a predetermined distance from the shoulder. The retention clip is received in the aperture in the wall structure. An umbrella-shaped valve member is over-molded to the core member. The umbrella-shaped valve member includes a convex surface facing in a direction away from the wall structure and a concave surface facing in a direction towards the wall structure. An outer peripheral edge of the umbrella-shaped valve member is disposed against the one face of the wall structure surrounding the passage.

Abstract: In one embodiment, a method includes establishing, by an identity agent installed on a device, a connection to a browser installed on the device and generating, by the identity agent, first device information, a public key, and a private key. The method also includes communicating, by the identity agent, the first device information and the public key to an authentication service and receiving, by the identity agent, a unique identifier from the authentication service. The method further includes generating, by the identity agent, a first signature of the first device information and communicating, by the identity agent, the first signature, the first device information, and the unique identifier to the browser.

Abstract: A beauty tool includes a handle portion configured to house an associated heating assembly and a bristle portion connected to the handle portion. The bristle portion includes a primary heating element configured to be heated by the associated heating assembly. A bristle base heated member is mounted to an outer periphery of the heating element. The bristle base heated member has a secondary heating element configured to be heated by the primary heating element. A non-conductive, heat insulating bristle spacer is secured between the bristle base heated member and the heating element. A bristle bar is secured by the bristle spacer and has bristles extending through the bristle spacer and the bristle base heated member. The bristle spacer is configured to thermally isolate the bristle bar from both the heating element and the bristle base heated member.

Abstract: In one embodiment, a method includes receiving, by a WebAuthn proxy, login prompt information from a browser. The WebAuthn proxy and the browser are installed on a device. The method also includes generating, by the WebAuthn proxy, a WebAuthn credential request based on the login prompt information and communicating, by the WebAuthn proxy, the WebAuthn credential request to a WebAuthn authenticator. The method further includes receiving, by the WebAuthn proxy, a WebAuthn response from the WebAuthn authenticator and communicating, by the WebAuthn proxy, the WebAuthn response to the browser.

Abstract: In one embodiment, a method includes receiving, by a WebAuthn proxy, login prompt information from a browser. The WebAuthn proxy and the browser are installed on a device. The method also includes generating, by the WebAuthn proxy, a WebAuthn credential request based on the login prompt information and communicating, by the WebAuthn proxy, the WebAuthn credential request to a WebAuthn authenticator. The method further includes receiving, by the WebAuthn proxy, a WebAuthn response from the WebAuthn authenticator and communicating, by the WebAuthn proxy, the WebAuthn response to the browser.

Abstract: Systems and methods for managing multi-objective alignments in imprinting (e.g., single-sided or double-sided) are provided. An example system includes rollers for moving a template roll, a stage for holding a substrate, a dispenser for dispensing resist on the substrate, a light source for curing the resist to form an imprint on the substrate when a template of the template roll is pressed into the resist on the substrate, a first inspection system for registering a fiducial mark of the template to determine a template offset, a second inspection system for registering the imprint on the substrate to determine a wafer registration offset between a target location and an actual location of the imprint, and a controller for controlling to move the substrate with the resist below the template based on the template offset, and determine an overlay bias of the imprint on the substrate based on the wafer registration offset.

Abstract: In an example method of forming an optical film for an eyepiece, a curable material is dispensed into a space between a first and a second mold surface. A position of the first mold surface relative to the second mold surface is measured using a plurality of sensors. Each sensor measures a respective relative distance along a respective measurement axis between a respective point on a planar portion of the first mold surface and a respective point on a planar portion of the second mold surface. The measurement axes are parallel to each other, and the points define corresponding triangles on the first and second mold surfaces, respectively. The position of the first mold surface is adjusted relative to the second mold surface based on the measured position, and the curable material is cured to form the optical film.

Abstract: In one embodiment, a method includes receiving, by a WebAuthn proxy, login prompt information from a browser. The WebAuthn proxy and the browser are installed on a device. The method also includes generating, by the WebAuthn proxy, a WebAuthn credential request based on the login prompt information and communicating, by the WebAuthn proxy, the WebAuthn credential request to a WebAuthn authenticator. The method further includes receiving, by the WebAuthn proxy, a WebAuthn response from the WebAuthn authenticator and communicating, by the WebAuthn proxy, the WebAuthn response to the browser.

Abstract: In one embodiment, a method includes establishing, by an identity agent installed on a device, a connection to a browser installed on the device and generating, by the identity agent, first device information, a public key, and a private key. The method also includes communicating, by the identity agent, the first device information and the public key to an authentication service and receiving, by the identity agent, a unique identifier from the authentication service. The method further includes generating, by the identity agent, a first signature of the first device information and communicating, by the identity agent, the first signature, the first device information, and the unique identifier to the browser.

Abstract: A computer-implemented method for retrieving information from information services and providing it to a public application programming interface (API) includes receiving a first request data message using a core discovery agent, the request data message including at least one requested datum, for which a value is sought, and at least one known datum, for which a value is known; calling a resource locator to request a location of an information service that provides a value for the requested datum; calling a resource façade to contact the information service; transmitting a first information service message including the requested datum and known datum from the resource façade to the information service; receiving a second information service message from the information service including a value for the requested datum; and transmitting a resolved data message including the requested datum and its value from the core discovery agent to the public API.

Abstract: Bifunctional molecules having first and second alpha-synuclein binding agents coupled by a linker are disclosed. The bifunctional molecules have potential utility in the diagnosis, treatment and/or prophylaxis of disorders in which alpha-synuclein is implicated, including Parkinson's disease. Methods of making and using the bifunctional molecules are disclosed.

Abstract: A tire tread includes a plurality of circumferential grooves, each of the plurality extending continuously in a tire circumferential direction. The plurality of circumferential grooves define a circumferentially extending shoulder rib. The shoulder rib has a plurality of shoulder elements. Each shoulder element is defined by two lateral shoulder grooves. Each shoulder element has an axially outer shoulder element and a corresponding axially adjacent and axially inner shoulder element separated by a circumferential groove. The axially outer shoulder elements each have a pair of angled outer lateral S-shaped blind grooves extending axially away from the inner shoulder elements.

Abstract: A tire includes a tread formed with tread elements that include a dual angled chamfer. The tire includes a pair of sidewalls extending radially outward to a ground-engaging tread. A plurality of circumferentially-extending grooves extend about the tread and define a plurality of ribs. A plurality of laterally-extending grooves cooperate with the circumferential grooves to divide the ribs into tread elements. A plurality of selected tread elements are formed with a dual angled chamfer. Each of the selected tread elements includes a body, a radially outer, ground-engaging surface, a chamfer side, and a dual angled chamfer that is formed in the body between the ground-engaging surface and the chamfer side.

Abstract: A computer-implemented method for retrieving information from information services and providing it to a public application programming interface (API) includes receiving a first request data message using a core discovery agent, the request data message including at least one requested datum, for which a value is sought, and at least one known datum, for which a value is known; calling a resource locator to request a location of an information service that provides a value for the requested datum; calling a resource façade to contact the information service; transmitting a first information service message including the requested datum and known datum from the resource façade to the information service; receiving a second information service message from the information service including a value for the requested datum; and transmitting a resolved data message including the requested datum and its value from the core discovery agent to the public API.