Patents by Inventor Jeremy Ling
Jeremy Ling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230277877Abstract: Methods of treating tumors by administering compounds to a patient are provided. Compounds such as drugs, may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.Type: ApplicationFiled: March 24, 2023Publication date: September 7, 2023Inventors: Vijay AGARWAL, Braden ELIASON, Jeremy LING
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Patent number: 11730980Abstract: Disclosed are methods of using planar acoustic waves for providing non-invasive sonodynamic therapy. The method includes acoustically coupling an array of flat piezoelectric transducers to a patient. A controller is configured to generate an electrical drive signal at a frequency selected from a range of frequencies, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a modulated planar acoustic wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.Type: GrantFiled: August 11, 2021Date of Patent: August 22, 2023Assignee: Alpheus Medical, Inc.Inventors: Vijay Agarwal, Braden Eliason, Jeremy Ling
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Patent number: 11724132Abstract: Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.Type: GrantFiled: October 5, 2022Date of Patent: August 15, 2023Assignee: Alpheus Medical, Inc.Inventors: Vijay Agarwal, Braden Eliason, Jeremy Ling
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Publication number: 20230226379Abstract: Methods of treating tumors by administering compounds to a patient are provided. Compounds such as pro drugs, e.g., 5-aminolevulinic acid (5-ALA), may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.Type: ApplicationFiled: March 24, 2023Publication date: July 20, 2023Inventors: Vijay AGARWAL, Braden ELIASON, Jeremy LING
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Patent number: 11617904Abstract: Methods of treating tumors by administering compounds to a patient are provided. Compounds such as pro drugs, e.g., 5-aminolevulinic acid (5-ALA), may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.Type: GrantFiled: April 29, 2022Date of Patent: April 4, 2023Assignee: Alpheus Medical, Inc.Inventors: Vijay Agarwal, Braden Eliason, Jeremy Ling
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Publication number: 20230037342Abstract: Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.Type: ApplicationFiled: October 5, 2022Publication date: February 9, 2023Inventors: Vijay AGARWAL, Braden ELIASON, Jeremy LING
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Patent number: 11491353Abstract: Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves that do not converge and do not diverge. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.Type: GrantFiled: August 11, 2021Date of Patent: November 8, 2022Assignee: Alpheus Medical, Inc.Inventors: Vijay Agarwal, Braden Eliason, Jeremy Ling
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Publication number: 20220257984Abstract: Methods of treating tumors by administering compounds to a patient are provided. Compounds such as pro drugs, e.g., 5-aminolevulinic acid (5-ALA), may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.Type: ApplicationFiled: April 29, 2022Publication date: August 18, 2022Inventors: Vijay AGARWAL, Braden ELIASON, Jeremy LING
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Patent number: 11318332Abstract: Methods of treating tumors by administering compounds to a patient are provided. Compounds such as pro drugs, e.g., 5-aminolevulinic acid (5-ALA), may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.Type: GrantFiled: August 11, 2021Date of Patent: May 3, 2022Assignee: Alpheus Medical, Inc.Inventors: Vijay Agarwal, Braden Eliason, Jeremy Ling
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Publication number: 20210369843Abstract: Methods of treating tumors by administering compounds to a patient are provided. Compounds such as pro drugs, e.g., 5-aminolevulinic acid (5-ALA), may be administered to the patient orally, by injection, intravenously, or topically, which then accumulate preferentially as compounds such as protoporphyrin IX (PpIX) in tumor cells. After such accumulation, compounds such as PpIX are then activated in various aspects to treat tumors cells, thereby treating cancer. Cancers such as glioblastoma may be treated.Type: ApplicationFiled: August 11, 2021Publication date: December 2, 2021Inventors: Vijay AGARWAL, Braden ELIASON, Jeremy LING
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Publication number: 20210370102Abstract: Disclosed are methods of using planar acoustic waves for providing non-invasive sonodynamic therapy. The method includes acoustically coupling an array of flat piezoelectric transducers to a patient. A controller is configured to generate an electrical drive signal at a frequency selected from a range of frequencies, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a modulated planar acoustic wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.Type: ApplicationFiled: August 11, 2021Publication date: December 2, 2021Inventors: Vijay AGARWAL, Braden ELIASON, Jeremy LING
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Publication number: 20210370103Abstract: Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves that do not converge and do not diverge. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.Type: ApplicationFiled: August 11, 2021Publication date: December 2, 2021Inventors: Vijay AGARWAL, Braden ELIASON, Jeremy LING
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Patent number: 9028250Abstract: A variety of improvements to the vibrating devices for dental remodeling are provided, including improved bite plate designs that accommodate common patient bite structure, a connector for a bite plate, a sizing tray for same, as well as better motors providing improved performance characteristics for an extraoral vibrator, and a completely intraoral vibrating dental plate with very thin cross section.Type: GrantFiled: November 9, 2009Date of Patent: May 12, 2015Assignee: OrthoAccel Technologies, Inc.Inventors: Glenn Spaulding, Jeremy Ling, Michael E. Kaufman, Michael K. Lowe
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Patent number: 8408157Abstract: This document discusses, among other things, an apparatus for painting a work surface including a handle housing. A disposable painting module is configured to be removably engaged with the handle housing. The painting module includes a paint applicator configured to be removably engaged with the handle housing. The paint applicator is configured to apply paint to the work surface. A paint reservoir is fluidly coupled with the paint applicator and is configured to be removably engaged with the handle housing. An urging mechanism is coupled to the handle housing and configured to interact with the paint reservoir to substantially uniformly discharge the paint from the paint reservoir and supply the paint to the paint applicator.Type: GrantFiled: March 13, 2008Date of Patent: April 2, 2013Assignee: Depingo, LLCInventor: Jeremy Ling
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Publication number: 20120330235Abstract: A drug delivery device includes a housing with a base and a cover that define an enclosure. A drug container disposed within the enclosure includes a drug reservoir configured to retain the drug therein. The drug container includes external features formed on an exterior of the drug container configured to interface with the housing so as to allow for dynamic movement relative to the housing to relieve stress on the rigid or flexible drug container when the needle assembly is actuated between the engaged and unengaged configurations. The drug delivery device includes a needle assembly with a needle and a drug channel connected between the drug container and needle assembly. A needle actuation mechanism is coupled to the needle assembly and actuatable between an engaged configuration and an unengaged configuration. The needle is extended from the housing in the engaged configuration and retracted in the housing in the unengaged configuration.Type: ApplicationFiled: June 25, 2012Publication date: December 27, 2012Applicant: RATIO, INC.Inventors: Ben J. Moga, Jeremy Ling, Jason Gerold
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Publication number: 20100055634Abstract: A variety of improvements to the vibrating devices for dental remodeling are provided, including improved bite plate designs that accommodate common patient bite structure, a connector for a bite plate, a sizing tray for same, as well as better motors providing improved performance characteristics for an extraoral vibrator, and a completely intraoral vibrating dental plate with very thin cross section.Type: ApplicationFiled: November 9, 2009Publication date: March 4, 2010Applicant: OrthoAccel Technologies, Inc.Inventors: Glenn SPAULDING, Jeremy Ling, Michael E. Kaufman, Michael K. Lowe
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Publication number: 20080223292Abstract: This document discusses, among other things, an apparatus for painting a work surface including a handle housing. A disposable painting module is configured to be removably engaged with the handle housing. The painting module includes a paint applicator configured to be removably engaged with the handle housing. The paint applicator is configured to apply paint to the work surface. A paint reservoir is fluidly coupled with the paint applicator and is configured to be removably engaged with the handle housing. An urging mechanism is coupled to the handle housing and configured to interact with the paint reservoir to substantially uniformly discharge the paint from the paint reservoir and supply the paint to the paint applicator.Type: ApplicationFiled: March 13, 2008Publication date: September 18, 2008Inventor: Jeremy Ling
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Publication number: 20050043581Abstract: The present disclosure relates to penile implants that are easier to implant and reduce trauma because they provide for a smaller effective width during implantation, after implantation, or both. The present disclosure also provides for a shorter tubing junction while reducing effective width, further reducing trauma to the body. In a first aspect, the penile implant includes a tubing junction that is smaller in effective diameter while implanted in the body. The penile implant includes an axially extending cylinder having an inflation chamber and a rear tip. The cylinder also includes a tubing junction disposed between the inflation chamber and rear tip and extending from the cylinder. The tubing junction includes a bore in fluid communication with the inflation chamber. In one example, this bore is in the strain relief of the tubing junction. The bore is configured to include a compound curve.Type: ApplicationFiled: October 5, 2004Publication date: February 24, 2005Inventors: Jeremy Ling, Randy Morningstar, Stephanie George