Abstract: The present invention provides novel isoquinolinone and quinolinone compounds that are inhibitors of mitochondrial RNA polymerase for treating various diseases such as cancer and others associated with metabolic disorders and mitochondrial dysfunction.

Abstract: The present invention provides novel hydroxy and alkoxy coumarin compounds that are inhibitors of mitochondrial RNA polymerase for treating various diseases such as cancer and others associated with metabolic disorders and mitochondrial dysfunction.

Abstract: In response to receiving a request from a querying entity, such as a seller of goods or services, embodiments of a service engine present to a client computing device of the querying entity a set of queries about goods or services sold by the querying entity and other characteristics of the business of the querying entity. The service engine may intelligently determine which queries to present based on responses to preceding queries. The service engine may then compare the entries in response to the queries against stored rules for a one or more of a plurality of tax jurisdictions, the stored rules being about establishing nexus for purposes of remitting transaction tax in the certain tax jurisdiction. The service engine may then determine information regarding potential lack of tax compliance of the querying entity based on the comparison, and notify accordingly.

Abstract: This system for recharging with electrical energy includes at least one connection terminal associated with a structure that is equipped with: —at least one terminal connector for a connecting cable formed, inter alia, from conductive wires intended to be connected to the vehicles with a view to performing a charge thereof using an energy source, and—a managing assembly for managing the operation of the system. Provision is made for an identification code (CID) associated with the connecting cable and for transmitting means for transmitting this code to the managing assembly with a view to permitting in particular the charge of the vehicle associated with the connecting cable. This system can be applied to recharge electric vehicles.

Abstract: In response to receiving a request from a querying entity, such as a seller of goods or services, embodiments of a service engine present to a client computing device of the querying entity a set of queries about goods or services sold by the querying entity and other characteristics of the business of the querying entity. The service engine may intelligently determine which queries to present based on responses to preceding queries. The service engine may then compare the entries in response to the queries against stored rules for a one or more of a plurality of tax jurisdictions, the stored rules being about establishing nexus for purposes of remitting transaction tax in the certain tax jurisdiction. The service engine may then determine information regarding potential lack of tax compliance of the querying entity based on the comparison, and notify accordingly.

Abstract: In response to receiving a request from a querying entity, such as a seller of goods or services, embodiments of a service engine present to a client computing device of the querying entity a set of queries about goods or services sold by the querying entity and other characteristics of the business of the querying entity. The service engine may intelligently determine which queries to present based on responses to preceding queries. The service engine may then compare the entries in response to the queries against stored rules for a one or more of a plurality of tax jurisdictions, the stored rules being about establishing nexus for purposes of remitting transaction tax in the certain tax jurisdiction. The service engine may then determine information regarding potential lack of tax compliance of the querying entity based on the comparison, and notify accordingly.

Abstract: An epicyclic gear train including a plurality of planet gears that are carried by a common planet carrier, the planet carrier comprising a support and a plurality of pins carried by the support, each pin having a fastening segment extending in a direction away from the support to a distal end, each planet gear being arranged around a respective one of the fastening segments and presenting a degree of freedom to move in rotation about an extension axis along which the fastening segment extends. A retaining link is carried by the pins and connects the pins together, each planet gear being arranged in a zone lying between the support and the retaining link, each pin presenting a restricted degree of freedom to move relative to the retaining link.

Abstract: An epicyclic gear train including a plurality of planet gears that are carried by a common planet carrier, the planet carrier comprising a support and a plurality of pins carried by the support, each pin having a fastening segment extending in a direction away from the support to a distal end, each planet gear being arranged around a respective one of the fastening segments and presenting a degree of freedom to move in rotation about an extension axis along which the fastening segment extends. A retaining link is carried by the pins and connects the pins together, each planet gear being arranged in a zone lying between the support and the retaining link, each pin presenting a restricted degree of freedom to move relative to the retaining link.