Abstract: Described herein are technique to enable the autonomous generation of configurations for a network environment, including but not limited to an edge network of a datacenter. Additional embodiments include prompt-based generation of network and device configurations and neural network based systems for adaptive network management.

Abstract: The present invention provides novel amino chromen-2-one compounds that are inhibitors of mitochondrial RNA polymerase for treating various diseases such as cancer and others associated with metabolic disorders and mitochondrial dysfunction.

Abstract: Disclosed are compounds according to Formula (1) which inhibit LONP1, and pharmaceutical compositions comprising compounds of the disclosure. Compounds and pharmaceutical compositions of the disclosure may be useful for the treatment of diseases and disorders associated with LONP1, including oncologic diseases and disorders, such as cancer, and diseases and disorders related to mitochondrial dysfunction, such as neurodegenerative disorders, metabolic disorders, and diseases associated with the aging process. The disclosure also relates to methods of using such compounds and compositions for the treatment of such diseases and disorders.

Abstract: Disclosed are compounds according to Formula (1) and Formula (2) which inhibit LONP1, and pharmaceutical compositions comprising compounds of the disclosure. Compounds and pharmaceutical compositions of the disclosure may be useful for the treatment of diseases and disorders associated with LONP1, including oncologic diseases and disorders, such as cancer, and diseases and disorders related to mitochondrial dysfunction, such as neurodegenerative disorders, metabolic disorders, and diseases associated with the aging process. The disclosure also relates to methods of using such compounds and compositions for the treatment of such diseases and disorders.

Abstract: A system includes a base configured to be positioned on a ground. The base includes a funnel configured to be positioned under a knife gate. The base also includes a first conveyor positioned under the funnel. The funnel is configured to direct a material from the knife gate onto a middle portion of the first conveyor. The system also includes a derrick having a first end that is coupled to the base. The derrick includes a second conveyor configured to receive the material from the first conveyor and to convey the material upward when the system is in an unfolded state. The derrick also includes a drum motor positioned proximate to an end of the derrick and configured to provide power to the second conveyor. The system also includes a first arm having a first end that is coupled to the end of the derrick.

Abstract: The disclosure deals with a system and method for the design of acoustic metamaterials based on liquid crystal skyrmions. Noise attenuation, sound focusing, and harvesting acoustic wave energy are challenging issues that the technological community currently faces. The disclosed thermodynamically driven metamaterial facilitates the design of unique architectures with several acoustic applications, including sound attenuation and acoustic energy harvesting. This disclosed structure includes spherical shells in a hexagonal arrangement (or cubic), which can be designed in any size and additively manufactured for end use applications.

Abstract: In response to receiving a request from a querying entity, such as a seller of goods or services, embodiments of a service engine present to a client computing device of the querying entity a set of queries about goods or services sold by the querying entity and other characteristics of the business of the querying entity. The service engine may intelligently determine which queries to present based on responses to preceding queries. The service engine may then compare the entries in response to the queries against stored rules for a one or more of a plurality of tax jurisdictions, the stored rules being about establishing nexus for purposes of remitting transaction tax in the certain tax jurisdiction. The service engine may then determine information regarding potential lack of tax compliance of the querying entity based on the comparison, and notify accordingly.

Abstract: This system for recharging with electrical energy includes at least one connection terminal associated with a structure that is equipped with: —at least one terminal connector for a connecting cable formed, inter alia, from conductive wires intended to be connected to the vehicles with a view to performing a charge thereof using an energy source, and—a managing assembly for managing the operation of the system. Provision is made for an identification code (CID) associated with the connecting cable and for transmitting means for transmitting this code to the managing assembly with a view to permitting in particular the charge of the vehicle associated with the connecting cable. This system can be applied to recharge electric vehicles.

Abstract: In response to receiving a request from a querying entity, such as a seller of goods or services, embodiments of a service engine present to a client computing device of the querying entity a set of queries about goods or services sold by the querying entity and other characteristics of the business of the querying entity. The service engine may intelligently determine which queries to present based on responses to preceding queries. The service engine may then compare the entries in response to the queries against stored rules for a one or more of a plurality of tax jurisdictions, the stored rules being about establishing nexus for purposes of remitting transaction tax in the certain tax jurisdiction. The service engine may then determine information regarding potential lack of tax compliance of the querying entity based on the comparison, and notify accordingly.

Abstract: In response to receiving a request from a querying entity, such as a seller of goods or services, embodiments of a service engine present to a client computing device of the querying entity a set of queries about goods or services sold by the querying entity and other characteristics of the business of the querying entity. The service engine may intelligently determine which queries to present based on responses to preceding queries. The service engine may then compare the entries in response to the queries against stored rules for a one or more of a plurality of tax jurisdictions, the stored rules being about establishing nexus for purposes of remitting transaction tax in the certain tax jurisdiction. The service engine may then determine information regarding potential lack of tax compliance of the querying entity based on the comparison, and notify accordingly.

Abstract: An epicyclic gear train including a plurality of planet gears that are carried by a common planet carrier, the planet carrier comprising a support and a plurality of pins carried by the support, each pin having a fastening segment extending in a direction away from the support to a distal end, each planet gear being arranged around a respective one of the fastening segments and presenting a degree of freedom to move in rotation about an extension axis along which the fastening segment extends. A retaining link is carried by the pins and connects the pins together, each planet gear being arranged in a zone lying between the support and the retaining link, each pin presenting a restricted degree of freedom to move relative to the retaining link.

Abstract: An epicyclic gear train including a plurality of planet gears that are carried by a common planet carrier, the planet carrier comprising a support and a plurality of pins carried by the support, each pin having a fastening segment extending in a direction away from the support to a distal end, each planet gear being arranged around a respective one of the fastening segments and presenting a degree of freedom to move in rotation about an extension axis along which the fastening segment extends. A retaining link is carried by the pins and connects the pins together, each planet gear being arranged in a zone lying between the support and the retaining link, each pin presenting a restricted degree of freedom to move relative to the retaining link.