Abstract: One aspect of the present invention provides a device for occluding a body cavity. In one embodiment, the occlusion device includes include a hub extending from an upstream end to a downstream end and along a central axis. A number of struts are attached to the upstream end and extend upstream from the hub. An expandable balloon is attached to the downstream end and extending downstream from the hub. Another aspect of the present invention provides a method for occluding fluid flow within in a body cavity including placing an occlusion device within the body cavity.

Abstract: Described are medical graft materials and devices which can be usefully modified with liquid additives such as cell suspensions, bioactive agents, or combinations of these. The medical graft materials and devices can have a first outer surface and a second outer surface and can define an internal chamber between the first outer surface and the second outer surface. The medical graft materials and devices can also have at least one region of the graft material interrupting the chamber and surrounded by the chamber. Also described are methods for making and using these medical graft materials and devices.

Abstract: One aspect of the present invention provides a device for occluding a body cavity. In one embodiment, the occlusion device includes include a hub extending from an upstream end to a downstream end and along a central axis. A number of struts are attached to the upstream end and extend upstream from the hub. An expandable balloon is attached to the downstream end and extending downstream from the hub. Another aspect of the present invention provides a method for occluding fluid flow within in a body cavity including placing an occlusion device within the body cavity.

Abstract: Described are medical graft materials and devices which can be usefully modified with liquid additives such as cell suspensions, bioactive agents, or combinations of these. Also described are methods for making and using these medical graft materials and devices.

Abstract: This invention provides, in certain aspects, unique devices and methods for treating fistulae. In one embodiment, an inventive device includes an elongate graft body having a proximal end and a distal end. The graft body is configurable to a first condition and a second condition, the second condition including the distal end deflected laterally relative to its position in the first condition of the body. The device also includes a tether, which is connected to the graft body, and is configured to traverse proximally along the body. The tether is manipulable to convert the graft body from the first condition to the second condition. Such a device may also include one or more additional tethers connected to the graft body. For instance, a second tether can be configured to extend distally from the distal end of the graft body, and may be effective in pulling the graft body along a fistula tract.

Abstract: This invention provides, in certain aspects, unique devices and methods for treating fistulae. In one embodiment, an inventive device includes an elongate graft body having a proximal end and a distal end. The graft body is configurable to a first condition and a second condition, the second condition including the distal end deflected laterally relative to its position in the first condition of the body. The device also includes a tether, which is connected to the graft body, and is configured to traverse proximally along the body. The tether is manipulable to convert the graft body from the first condition to the second condition. Such a device may also include one or more additional tethers connected to the graft body. For instance, a second tether can be configured to extend distally from the distal end of the graft body, and may be effective in pulling the graft body along a fistula tract.