Abstract: Described herein are polypeptides comprising an FGF17, IGF2, or BMP7 amino acid sequence and an amino acid sequence from a heterologous polypeptide useful for the treatment of soft-tissue and muscle diseases, disorders, and injuries. Also described herein are synergistic combinations of a Fibroblast Growth Factor Receptor agonist and a glycosaminoglycan, an Insulin-like Growth Factor 1 Receptor (IGF1R) agonist and a short chain fatty acid, and BMP receptor agonists and mTOR activators and/or glycosaminoglycans. Also described are methods of treating muscle and soft-tissue diseases comprising administering the polypeptides and/or synergistic compositions.

Abstract: An optical construction includes a reflective polarizer and an optically diffusive film disposed on the reflective polarizer. The reflective polarizer includes an outer layer including a plurality of first particles partially protruding from a first major surface thereof to form a structured major surface. A first optically diffusive layer is conformably disposed on the structured major surface. The optically diffusive film includes a second optically diffusive layer including a plurality of nanoparticles dispersed therein, and a structured layer including a structured major surface. For a substantially normally incident light and a visible wavelength range from about 450 nm to about 650 nm and an infrared wavelength range from about 930 nm to about 970 nm, the second optically diffusive layer has an average specular transmittance Vs in the visible wavelength range and an average specular transmittance Is in the infrared wavelength range, where Is/Vs?2.5.

Abstract: Described herein are therapeutic compositions comprising heparin-associated polypeptides useful for the treatment of soft-tissue and muscle diseases, disorders, and injuries.

Abstract: Aspects of the present disclosure relate to data deduplication (dedup) techniques for storage arrays. In embodiments, a sequence of input/output (IO) operations in an IO stream received from one or more host devices by a storage array are identified. Additionally, a determination can be made as to whether a set of previously received IO operations match the identified IO sequence based on a time series relationship between the identified IO sequence and the previously received IO operations. Further, one or more data deduplication (dedup) techniques can be performed on the matching IO sequence.

Abstract: A system may include one or more enterprise computing (EC) systems and a computing platform, which may include a sales data module, a content selection module, an account module, or a data storage. Each EC system may track target sales data for targets and send the target sales data to the computing platform. The sales data module may receive the target sales data, store the target sales data as sales data, dynamically calculate a threshold based on the sales data, and determine, from the target sales data associated with an target, whether the target sales data for the target is below the threshold. The content selection module may, in response to the target sales data for the target being below the threshold, select training content for the target, and send a notification to the target. The notification may include a link to access the training content.

Abstract: Described herein are therapeutic compositions comprising heparin-associated polypeptides useful for the treatment of soft-tissue and muscle diseases, disorders, and injuries.

Abstract: The meta data containing count and key fields of CKD records are reversibly decoupled from the user data of the data field so that the data can be deduplicated. Multiple CKD records may be coalesced into a larger size CKD track. The coalesced meta data is compressed and stored in a CKD hash table. The user data is hashed, and the hash is used as a hash key that is associated with the compressed meta data in the CKD hash table. When the hash of user data associated with a CKD write IO matches the hash key of an existing entry in the table, data duplication is indicated. The compressed meta data is added to the entry and the user data is deduplicated by creating storage system meta data that points to the pre-existing copy of the user data. The storage system metadata includes unique information that enables the corresponding compressed metadata to be subsequently located in the hash table to reassemble the CKD records.

Abstract: Described herein are polypeptides comprising an FGF17, IGF2, or BMP? amino acid sequence and an amino acid sequence from a heterologous polypeptide useful for the treatment of soft-tissue and muscle diseases, disorders, and injuries. Also described herein are synergistic combinations of a Fibroblast Growth Factor Receptor agonist and a glycosaminoglycan, an Insulin-like Growth Factor 1 Receptor (IGF1R) agonist and a short chain fatty acid, and BMP receptor agonists and mTOR activators and/or glycosaminoglycans. Also described are methods of treating muscle and soft-tissue diseases comprising administering the polypeptides and/or synergistic compositions.

Abstract: A machine vision functionality deployment system for transcoding a raw machine vision data signal in an existing machine vision system for capturing sensed information from a substrate. Provided is a digital data interface bus to: receive raw machine vision digital data signals from an acquisition device. The raw machine vision digital data signals are in an acquisition device format and to output a transcoded machine vision digital data signal to a consumption device in a consumption device format. A digital data processor in communication to the digital data interface bus operable to: identify digital data elements associated with an artifact of the substrate in the raw machine vision digital data signal, wherein the artifact is not detectable by the consumption device; transcode the raw machine vision digital data signal by rendering the artifact detectable in the transcoded machine vision digital data signal by the consumption device.

Abstract: An optical construction includes a reflective polarizer and an optically diffusive film disposed on the reflective polarizer. The reflective polarizer includes an outer layer including a plurality of first particles partially protruding from a first major surface thereof to form a structured major surface. A first optically diffusive layer is conformably disposed on the structured major surface. The optically diffusive film includes a second optically diffusive layer including a plurality of nanoparticles dispersed therein, and a structured layer including a structured major surface. For a substantially normally incident light and a visible wavelength range from about 450 nm to about 650 nm and an infrared wavelength range from about 930 nm to about 970 nm, the second optically diffusive layer has an average specular transmittance Vs in the visible wavelength range and an average specular transmittance Is in the infrared wavelength range, where Is/Vs?2.5.

Abstract: Described herein are polypeptides comprising an FGF17, IGF2, or BMP7 amino acid sequence and an amino acid sequence from a heterologous polypeptide useful for the treatment of soft-tissue and muscle diseases, disorders, and injuries. Also described herein are synergistic combinations of a Fibroblast Growth Factor Receptor agonist and a glycosaminoglycan, an Insulin-like Growth Factor 1 Receptor (IGF1R) agonist and a short chain fatty acid, and BMP receptor agonists and mTOR activators and/or glycosaminoglycans. Also described are methods of treating muscle and soft-tissue diseases comprising administering the polypeptides and/or synergistic compositions.

Abstract: Reflective stacks including heat spreading layers are described. In particular, reflective stacks including polymeric multilayer reflectors. Heat spreading layers may include natural or synthetic graphite or copper.

Abstract: A task generator runs on a data storage system in which multiple compute nodes allocate portions of local memory to a remotely accessible shared memory. The task generator is responsive to a primary task to be performed on a storage object to generate separate, per-compute node secondary tasks corresponding to the primary task. Each of the separate secondary tasks specifies at least one attribute of metadata associated with the storage object and at least one task logic function. Each of the plurality of compute nodes performs the separate secondary task generated for that compute node by scanning the local portion of the shared memory based on the attribute to identify matching pages of the metadata associated with the storage object and performs the task logic function on the identified matching pages of the metadata associated with the storage object to generate a local result. The task generator combines the local results to perform the primary task.

Abstract: A Ransomware Activity Detection System (RADS) characterizes historic read/write IO activity on a storage volume, and also characterizes historic data characteristics of the storage volume, such as the percentage reducibility of the data held in the storage volume. The RADS monitors the storage volume to identify differences between current read/write IO activity and historic read/write IO activity, as well as difference between current data characteristics of the storage volume and historic data characteristics of the storage volume. When the RADS detects a significant difference in read/write IO activity on a storage volume, that is coupled with a significant changes to the data characteristics of the storage volume, the RADS protects the storage volume and generates an alert of the possible occurrence of a ransomware attack. Protection may occur prior in connection with any bulk read operation to proactively protect storage volumes against ransomware attacks.

Abstract: Optical films and stacks include at least one optically diffusive layer. The optically diffusive layer can include a plurality of nanoparticles and a polymeric material bonding the nanoparticles to each other to form a plurality of nanoparticle aggregates defining a plurality of voids therebetween. For substantially normally incident light and a visible wavelength range from about 450 nm to about 650 nm and an infrared wavelength range from about 930 nm to about 970 nm: in the visible wavelength range, the optical film or optically diffusive layer has an average specular transmittance Vs; and in the infrared wavelength range, the optical film or optically diffusive layer has an average total transmittance It and an average specular transmittance Is, Is/It?0.6, Is/Vs?2.5.

Abstract: A display system for sensing a finger of a user applied to the display system includes a display panel; a sensor for sensing the finger; a sensing light source configured to emit a first light having a first wavelength W1; and a reflective polarizer disposed between the display panel and the sensor. For a substantially normally incident light, an optical transmittance of the reflective polarizer versus wavelength for a first polarization state has a band edge such that for a first wavelength range extending from a smaller wavelength L1 to a greater wavelength L2 and including W1, where 30 mn?L2?L1?50 nm and L1 is greater than and within about 20 nm of a wavelength L3 corresponding to an optical transmittance of about 50% along the band edge, the optical transmittance has an average of greater than about 75%.

Abstract: Systems including one or both of a light emitter or a light receiver or a detectable object; and an optical filter adjacent one or both of the light emitter or the light receiver, wherein the optical filter includes at least one wavelength transmission selective layer an absorber component, wherein the wavelength transmission selective layer at least partially reduces the transmission of wavelengths from 701 nm to 849 nm incident thereon.

Abstract: Described herein are polypeptides comprising an IGF2 amino acid sequence and an amino acid sequence from a heterologous polypeptide useful for the treatment of soft-tissue and muscle diseases, disorders, and injuries. Mutations within the IGF2 amino acid sequence improved the stability of the molecule by reducing backbone cleavage. Also described herein are synergistic combinations of an Insulin-like Growth Factor 1 Receptor (IGF1R) agonist and a short chain fatty acid. Also described are methods of treating muscle and soft-tissue diseases comprising administering the polypeptides and/or synergistic compositions.

Abstract: A deduplication engine maintains a deduplication hash table containing a plurality of fingerprint entries identifying a track of current data and a hash value computed from the data currently stored at the identified track. A hash table manager implements a dynamic deduplication hash table management process, that includes a fingerprint entry purge process and a fingerprint entry re-entry process. The purge process is implemented on the deduplication hash table to remove selected fingerprint entries of tracks of data currently stored on the managed drives from the deduplication hash table based on a first set of Thin Device (TDev) selection rules and a second set of track selection purge rules. The re-entry process is implemented on the deduplication hash table to re-enter selected fingerprint entries into the deduplication hash table based on a third set of TDev selection rules and a fourth set of track selection re-entry rules.

Abstract: A computer implemented method comprises receiving a mesh representing a 3D object, the mesh comprising a plurality of 2D shapes, receiving a strand feature comprising a plurality of virtual strands, and associating each strand of the plurality of virtual strands with a 2D shape of the mesh.