Abstract: Provided are compositions containing extracellular vesicles from microalgae (MEVs) that are exogenously loaded with bioactive cargo or other cargo of interest, such as for therapeutic, industrial, diagnostic, and cosmetic uses. The MEVs have a variety of applications as therapeutics, including as vaccines, as anti-cancer therapeutics, as diagnostics, and other such uses.

Abstract: Disclosed is a method for the culture of photosynthetic organisms selected from among microalgae, cyanobacteria and macroalgae using a continuous or discontinuous CO2 source.

Abstract: Disclosed is a method for the culture of photosynthetic organisms selected from among microalgae, cyanobacteria and macroalgae using a continuous or discontinuous CO2 source.

Abstract: A method for preparing a liquid extract rich in phycocyanin from cyanobacteria or microalgae containing phycocyanin in solution, comprising a step of carrying out the cellular lysis of an aqueous suspension of said fresh cyanobacteria or microalgae, a step of macerating the lysate obtained, for several hours in a solution of divalent cations, while releasing the water-soluble molecules in the extracellular space, and one or more steps of clarifying and concentrating the suspension in order to isolate the water-soluble molecules, among them phycocyanin. This method is performed at a pH between 5 and 8.5, at room temperature, without drying.

Abstract: A method for producing membrane polysaccharides from an organism selected from micro-organisms, unicellular organisms and filamentous fungi, the method including at least one step of extracting the membrane polysaccharides as well as a smaller-scale extraction of the soluble proteins, by mechanical treatment of the organism in a ball mill or by physical treatment of the organism by means of ultrasounds.

Abstract: The present invention concerns a module for a photobioreactor suitable for being assembled to an identical adjacent module, comprising: —a panel having a first face and a second face, opposite the first face, the first face delimiting, with the second face of the adjacent panel, a cavity suitable for containing a culture medium when the modules are assembled, the cavity (14) having a thickness of between 1 millimetre and 2 centimetres, and —a gas injection device, capable of injecting gas bubbles into the culture medium contained in the cavity, such that the bubbles rise along the faces of the panels.

Abstract: A method for producing membrane polysaccharides from an organism selected from micro-organisms, unicellular organisms and filamentous fungi, the method including at least one step of extracting the membrane polysaccharides as well as a smaller-scale extraction of the soluble proteins, by mechanical treatment of the organism in a ball mill or by physical treatment of the organism by means of ultrasounds.

Abstract: The method for treating a microalgal biomass, characterized in the following steps: having a microalgal biomass comprising at least 15% by weight of lipids relative to the total weight of the biomass and having a dry matter concentration of between 1 g/l and 200 g/l, milling said biomass by a bead mill, operated under the following conditions: the mean diameter of the beads (dGM) ranges from 0.2 to 2.5×10?3 m, preferably from 0.4 to 1.0×10?3 m and is preferably approximately 0.6×10?3 m, the blade-tip agitation speed (?) ranges from 4 to 50 m·s?1, preferably from 5 to 20 m·s?1 and is preferably approximately 8 m·sec?1; recovering the composition obtained.

Abstract: A method is provided for extracting cellular compounds from micro-organisms. The method includes culturing the micro-organisms and extracting the cellular compounds from the micro-organisms. Each step is carried out in a continuous manner, wherein the extraction step is carried out separately from the culture step and in conditions of biocompatibility with the micro-organisms. The method further includes at least one step of recovering the cellular compounds and at least one step of recirculating the micro-organisms towards the culture step.

Abstract: The invention relates to a photoreactor (1) comprising a contained reaction chamber (15), wherein the chamber (15) is separated from the exterior by a light-capturing wall (11) and another wall (12), the capturing wall and the other wall being parallel to one another; characterized in that the photoreactor (1) additionally comprises a thermal valve (13) placed against the other wall (12) for passively controlling the increase in heat inside the chamber (15) due to the radiation passing through the capturing wall (11) in order to maintain the temperature in at least one part of the chamber (15) under a threshold temperature (Ts), the thermal valve (13) being made of a phase-change material.

Abstract: The invention relates to a photobioreactor (1) for the culture of cells, comprising a runoff substrate (2) having a surface inclined at an average slope along a direction of inclination (I-I) on which a solution flows and including an upstream side (21) and a downstream side (22), said solution comprising cells in suspension. The invention is characterised in that the photobioreactor (1) comprises an upflow element (3) that conveys the solution from the downstream end (22) to the upstream end (21) along an upflow direction that is substantially parallel to the direction of inclination (I-I).

Abstract: The present invention thus aims to propose a bioreactor which has an improved yield (concentration, productivity), which is capable of culturing microorganisms sensitive to mechanical stresses, and which is energy-saving. The subject matter of the invention is a method for culturing microorganisms in suspension in a culture medium, in which the microorganism suspension is made to flow in a channel which has means for generating mixing by Lagrangian chaos when the microorganism suspension circulates in said channel.

Abstract: HA method is provided for extracting cellular compounds from micro-organisms. The method includes culturing the micro-organisms and extracting the cellular compounds from the micro-organisms. Each step is carried out in a continuous manner, wherein the extraction step is carried out separately from the culture step and in conditions of biocompatibility with the micro-organisms. The method further includes at least one step of recovering the cellular compounds and at least one step of recirculating the micro-organisms towards the culture step.

Abstract: The invention relates to a method of improving the transfer in an annular biological reaction chamber defined by coaxial inner and outer walls (11, 12) and in which there flows a liquid reaction medium containing a culture of microorganisms or of cells from vegetable or animal macroorganisms in suspension. At least one of the walls is an exchange wall enabling gaseous or liquid matter to be transferred or allowing light to pass through. The reaction medium is subjected to a turbulent primary flow that is helical and that under the action of centrifugal force creates rotary secondary vortices so as to encourage renewal of the culture in the vicinity of the exchange wall.

Abstract: The invention relates to a method of improving the transfer in an annular biological reaction chamber defined by coaxial inner and outer walls (11, 12) and in which there flows a liquid reaction medium containing a culture of microorganisms or of cells from vegetable or animal macroorganisms in suspension. At least one of the walls is an exchange wall enabling gaseous or liquid matter to be transferred or allowing light to pass through. The reaction medium is subjected to a turbulent primary flow that is helical and that under the action of centrifugal force creates rotary secondary vortices so as to encourage renewal of the culture in the vicinity of the exchange wall.