Abstract: A hip loading board for exercise includes linear-motion elements. The linear-motion elements include linear-motion bearing motion elements (e.g. a linear slide). One or more linear-motion elements of the hip loading board can be designed to provide free motion in one direction. Example linear slides (compound slides, dovetail slides, rack slides, ball bearing-based slides, magnetic slides, etc.) can be non-motorized dovetail slides, ball bearing slides, roller slides, etc. that provide a low-friction linear movement. The hip loading board can include one or more interchangeable resistance elements that provide a force to return a moving plate to a start position. The interchangeable resistance elements may also provide a linear resistance (e.g. any material which creates a constant resistance or tension, variable resistance or tension, etc.).

Abstract: Methods of sequencing molecules based on luminescence lifetimes and/or intensities are provided. In some aspects, methods of sequencing nucleic acids involve determining the luminescence lifetimes, and optionally luminescence intensities, of a series of luminescently labeled nucleotides incorporated during a nucleic acid sequencing reaction.

Abstract: Compositions useful for the detection of single molecules in a sample are provided. In some aspects, the disclosure provides a nucleotide connected to a nucleic acid comprising a FRET label comprising at least three luminescent molecules. In some embodiments, the nucleic acids described herein comprise one or more structural features that provide enhanced fluorescence intensity. In some aspects, methods of sequencing using the labeled nucleotides of the disclosure are provided.

Abstract: Aspects of the application provide methods of identifying and sequencing proteins, polypeptides, and amino acids, and compositions useful for the same. In some aspects, the application provides methods of obtaining data during a degradation process of a polypeptide, and outputting a sequence representative of the polypeptide. In some aspects, the application provides amino acid recognition molecules comprising a shielding element that enhances photostability in polypeptide sequencing reactions.

Abstract: Compositions useful for the detection of single molecules in a sample are provided. In some aspects, the disclosure provides a nucleic acid connected to a nucleotide and two or more luminescent labels. In some embodiments, the nucleic acids described herein comprise one or more structural features that provide enhanced fluorescence intensity. In some aspects, methods of sequencing using the labeled nucleotides of the disclosure are provided.

Abstract: The present invention provides a lid assembly and fluid container having the lid assembly

Abstract: Sets of power amplifier branches (which comprise an RF/microwave amplifier stage) are power combined within each stage and each set of power amplifier branches are biased in different classes of operation by bias circuits possessing different impedance characteristics such that the fundamental frequency components present at the output are in-phase with one another and the IMD3 components are anti-phase over a broad range of power levels. The RF input signal is provided by the output of the previous stage of the RF/microwave amplifier. The output of each stage is formed by power combining sets of these power amplifier branches, each of which are separately biased, so the fundamental components are additive resulting in the maximum possible output power and the IM3 components cancel partially or completely.