Patents by Inventor Jeremy RICHTER

Jeremy RICHTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED NITROGEN CONTAINING COMPOUNDS
    Publication number: 20230124468
    Abstract: Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is: each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3a, R3b, L1, B, V, Y, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Application
    Filed: October 5, 2022
    Publication date: April 20, 2023
    Inventors: Navnath Dnyanoba Yadav, Rajeev S. Bhide, Rajesh Onkardas Bora, Prashantha Gunaga, Manoranjan Panda, Eldon Scott Priestley, Jeremy Richter
  • BIARYLMETHYL HETEROCYCLES
    Publication number: 20230045357
    Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are biased agonists, or ?-Arrestin agonists of the angiotensin II receptor, which may be used as medicaments.
    Type: Application
    Filed: July 11, 2022
    Publication date: February 9, 2023
    Applicants: Université de Montréal, Bristol-Myers Squibb Company
    Inventors: Eldon Scott PRIESTLEY, Samuel Kaye REZNIK, Edward H. RUEDIGER, James R. GILLARD, Oz Scott HALPERN, Wen JIANG, Jeremy RICHTER, Rejean RUEL, Sasmita TRIPATHY, Wu YANG, Xiaojun ZHANG
  • Biarylmethyl heterocycles
    Patent number: 11407733
    Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are biased agonists, or ?-Arrestin agonists of the angiotensin II receptor, which may be used as medicaments.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: August 9, 2022
    Assignees: Bristol-Myers Squibb Company
    Inventors: Eldon Scott Priestley, Samuel Kaye Reznik, Edward H. Ruediger, James R. Gillard, Oz Scott Halpern, Wen Jiang, Jeremy Richter, Rejean Ruel, Sasmita Tripathy, Wu Yang, Xiaojun Zhang
  • Substituted bicyclic heterocyclic compounds
    Patent number: 10851108
    Abstract: Disclosed are compounds of Formula (I), or a salt thereof, wherein: X is CR4 or N; Y is CR4 or N, provided that Y is N only if X is N; R1 is Formulae (A) or (B); each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, R3, R4, L1, R1a, R1b, R1c, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: December 1, 2020
    Assignee: Bristol-Myers Squibb Company
    Inventors: Prashantha Gunaga, Jeremy Richter, Navnath Dnyanoba Yadav, Manoranjan Panda, Sreenivasulu Godesi
  • SUBSTITUTED NITROGEN CONTAINING COMPOUNDS
    Publication number: 20200339550
    Abstract: Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is: each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3a, R3b, L1, B, V, Y, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Application
    Filed: July 14, 2020
    Publication date: October 29, 2020
    Inventors: Navnath Dnyanoba Yadav, Rajeev S. Bhide, Rajesh Onkardas Bora, Prashantha Gunaga, Manoranjan Panda, Eldon Scott Priestley, Jeremy Richter
  • Substituted bicycle heterocyclic derivatives useful as ROMK channel inhibitors
    Patent number: 10723723
    Abstract: Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is (II) or (III); each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3, L1, L2, R1a, R1b, R1c, and n are define herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: July 28, 2020
    Assignee: Bristol-Myers Squibb Company
    Inventors: Prashantha Gunaga, Rajeev S. Bhide, Rajesh Onkardas Bora, Manoranjan Panda, Navnath Dnyanoba Yadav, Eldon Scott Priestley, Jeremy Richter
  • SUBSTITUTED NITROGEN CONTAINING COMPOUNDS
    Publication number: 20200109135
    Abstract: Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is: each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3a, R3b, L1, B, V, Y, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Application
    Filed: November 11, 2019
    Publication date: April 9, 2020
    Inventors: Navnath Dnyanoba Yadav, Rajeev S. Bhide, Rajesh Onkardas Bora, Prashantha Gunaga, Manoranjan Panda, Eldon Scott Priestley, Jeremy Richter
  • Substituted nitrogen containing compounds
    Patent number: 10501449
    Abstract: Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is: each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3a, R3b, L1, B, V, Y, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: December 10, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Navnath Dnyanoba Yadav, Rajeev S. Bhide, Rajesh Onkardas Bora, Prashantha Gunaga, Manoranjan Panda, Eldon Scott Priestley, Jeremy Richter
  • SUBSTITUTED BICYCLE HETEROCYCLIC DERIVATIVES USEFUL AS ROMK CHANNEL INHIBITORS
    Publication number: 20190248769
    Abstract: Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is (II) or (III); each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3, L1, L2, R1a, R1b, R1c, and n are define herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Application
    Filed: November 2, 2017
    Publication date: August 15, 2019
    Inventors: Prashantha Gunaga, Rajeev S. Bhide, Rajesh Onkardas Bora, Manoranjan Panda, Navnath Dnyanoba Yadav, Eldon Scott Priestley, Jeremy Richter
  • BIARYLMETHYL HETEROCYCLES
    Publication number: 20190202808
    Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are biased agonists, or ?-Arrestin agonists of the angiotensin II receptor, which may be used as medicaments.
    Type: Application
    Filed: June 28, 2017
    Publication date: July 4, 2019
    Inventors: Eldon Scott PRIESTLEY, Samuel Kaye REZNIK, Edward H. RUEDIGER, James R. GILLARD, Oz Scott HALPERN, Wen JIANG, Jeremy RICHTER, Rejean RUEL, Sasmita TRIPATHY, Wu YANG, Xiaojun ZHANG
  • SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS
    Publication number: 20190127380
    Abstract: Disclosed are compounds of Formula (I), or a salt thereof, wherein: X is CR4 or N; Y is CR4 or N, provided that Y is N only if X is N; R1 is Formulae (A) or (B); each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, R3, R4, L1, R1a, R1b, R1c, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Application
    Filed: April 19, 2017
    Publication date: May 2, 2019
    Inventors: Prashantha Gunaga, Jeremy Richter, Navnath Dnyanoba Yadav, Manoranjan Panda, Sreenivasulu Godesi
  • SUBSTITUTED NITROGEN CONTAINING COMPOUNDS
    Publication number: 20180346453
    Abstract: Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is: each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3a, R3b, L1, B, V, Y, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Application
    Filed: May 31, 2018
    Publication date: December 6, 2018
    Inventors: Navnath Dnyanoba Yadav, Rajeev S. Bhide, Rajesh Onkardas Bora, Prashantha Gunaga, Manoranjan Panda, Eldon Scott Priestley, Jeremy Richter
  • Macrocyclic factor VIIa inhibitors
    Patent number: 9657006
    Abstract: The present invention provides compounds of Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: May 23, 2017
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Jeremy Richter, J. Alex Bates, Daniel L. Cheney
  • MACROCYCLIC FACTOR VIIA INHIBITORS
    Publication number: 20160115159
    Abstract: The present invention provides compounds of Formula (I) as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.
    Type: Application
    Filed: June 11, 2014
    Publication date: April 28, 2016
    Inventors: Jeremy RICHTER, J. Alex BATES, Daniel L. CHENEY
  • Substituted nitrogen containing compounds
    Patent number: RE49700
    Abstract: Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is: each W is independently NR1b or O; Z is a bond or CHR1d; and R1, R2, Rd, R3a, R3b, L1, B, V, Y, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
    Type: Grant
    Filed: February 23, 2021
    Date of Patent: October 17, 2023
    Assignee: Bristol-Myers Squibb Company
    Inventors: Navnath Dnyanoba Yadav, Rajeev S. Bhide, Rajesh Onkardas Bora, Prashantha Gunaga, Manoranjan Panda, Eldon Scott Priestley, Jeremy Richter