Patents by Inventor Jeremy S. York

Jeremy S. York has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAPT RNA interference agents
    Patent number: 11926827
    Abstract: Provided herein are MAPT RNAi agents and compositions comprising a MAPT RNAi agent. Also provided herein are methods of using the MAPT RNAi agents or compositions comprising a MAPT RNAi agent for reducing MAPT expression and/or treating tauopathy in a subject.
    Type: Grant
    Filed: May 3, 2023
    Date of Patent: March 12, 2024
    Assignee: ELI LILLY AND COMPANY
    Inventors: Barbara Calamini, Sarah Katharina Fritschi, Rebecca Ruth Miles, Andrew Peter McCarthy, Douglas Raymond Perkins, Keith Geoffrey Phillips, Kaushambi Roy, Isabel Cristina Gonzalez Valcarcel, Jibo Wang, Shih-Ying Wu, Jeremy S. York
  • TRANSFERRIN RECEPTOR BINDING PROTEINS AND CONJUGATES
    Publication number: 20240059784
    Abstract: Provided herein are proteins comprising one monovalent human TfR binding domain (“human TfR binding proteins”), proteins comprising one monovalent mouse TfR binding domain (“mouse TfR binding proteins”), conjugates comprising such human or mouse TfR binding proteins, e.g., human TfR binding proteins-dsRNA conjugates, pharmaceutical compositions comprising human TfR binding proteins or conjugates, and methods of treating CNS diseases (e.g., neurodegenerative disease such as neurodegenerative synucleinopathy or tauopathy) using human TfR binding proteins or conjugates.
    Type: Application
    Filed: August 7, 2023
    Publication date: February 22, 2024
    Inventors: Riazul Alam, Alberto Alvarado, Forest Hoyt Andrews, Nicholas Alan Babb, Deepa Balasubramaniam, Guillermo S. Cortez, Johnny Eugene Croy, David Albert Driver, Ross Edward Fellows, Daniel Girard, Lacie Chauvigne-Hines, Feng Liu, Hiroaki Tani, Isabel C. Gonzalez Valcarcel, Scott Alan Lawrence, Nalini Hosahalli Kulkarni, Jeremy S York
  • MAPT RNA INTERFERENCE AGENTS
    Publication number: 20230340482
    Abstract: Provided herein are MAPT RNAi agents and compositions comprising a MAPT RNAi agent. Also provided herein are methods of using the MAPT RNAi agents or compositions comprising a MAPT RNAi agent for reducing MAPT expression and/or treating tauopathy in a subject.
    Type: Application
    Filed: May 3, 2023
    Publication date: October 26, 2023
    Inventors: Barbara Calamini, Sarah Katharina Fritschi, Rebecca Ruth Miles, Andrew Peter McCarthy, Douglas Raymond Perkins, Keith Geoffrey Phillips, Kaushambi Roy, Isabel Cristina Gonzalez Valcarcel, Jibo Wang, Shih-Ying Wu, Jeremy S. York
  • MAPT RNA INTERFERENCE AGENTS
    Publication number: 20230212576
    Abstract: Provided herein are MAPT RNAi agents and compositions comprising a MAPT RNAi agent. Also provided herein are methods of using the MAPT RNAi agents or compositions comprising a MAPT RNAi agent for reducing MAPT expression and/or treating tauopathy in a subject.
    Type: Application
    Filed: December 12, 2022
    Publication date: July 6, 2023
    Inventors: Barbara Calamani, Sarah Katharina Fritschi, Rebecca Ruth Miles, Andrew Peter McCarthy, Douglas Raymond Perkins, Keith Geoffrey Phillips, Kaushambi Roy, Isabel Cristina Gonzalez Valcarcel, Jibo Wang, Shih-Ying Wu, Jeremy S. York