Patents by Inventor Jeremy Sanderson

Jeremy Sanderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ITPase gene polymorphisms associated with adverse durg reactions to azathioprine therapy
    Publication number: 20050202483
    Abstract: The present invention provides methods for predicting a patient's risk of an adverse drug reaction to a thiopurine drug such as AZA or 6-MP by genotyping the patient for a polymorphism in the gene encoding ITPase (ITPA). The present invention also provides methods for predicting a patient's risk of an adverse drug reaction to a thiopurine drug by determining a level of ITPase activity or ITP in a sample from the patient. The present invention further provides methods for optimizing therapeutic efficacy in a patient receiving a thiopurine drug by determining whether the patient should be given an alternative drug based on the presence or absence of a polymorphism in the ITPA gene.
    Type: Application
    Filed: February 18, 2005
    Publication date: September 15, 2005
    Applicant: Guy's and St. Thomas' NHS Foundation Trust
    Inventors: Jeremy Sanderson, Anthony Marinaki