Patents by Inventor Jeremy Schofield

Jeremy Schofield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Time lapse sequencing: a convertible-nucleoside approach to enrichment-free analysis of RNA dynamics
    Patent number: 11098342
    Abstract: The invention provides methods and compositions for generating mutations in new nucleic acid molecules through incorporation of a transformable nucleoside into the nucleic acid and subsequent transformation of the nucleoside through oxidative-nucleophilic-aromatic-substitution chemistry, referred to as TimeLapse chemistry. The invention further provides methods for detecting the mutations, referred to as TimeLapse-seq.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: August 24, 2021
    Assignee: Yale University
    Inventors: Matthew Simon, Jeremy Schofield
  • Time Lapse Sequencing: A convertible-nucleoside approach to enrichment-free analysis of RNA dynamics
    Publication number: 20180282789
    Abstract: The invention provides methods and compositions for generating mutations in new nucleic acid molecules through incorporation of a transformable nucleoside into the nucleic acid and subsequent transformation of the nucleoside through oxidative-nucleophilic-aromatic-substitution chemistry, referred to as TimeLapse chemistry. The invention further provides methods for detecting the mutations, referred to as TimeLapse-seq.
    Type: Application
    Filed: March 30, 2018
    Publication date: October 4, 2018
    Inventors: Matthew Simon, Jeremy Schofield