Abstract: A sensor assembly for impact detection for use in a motor vehicle including a housing, a pressure transducer sensitive to pressure, and an accelerometer sensitive to acceleration. The pressure transducer and the accelerometer are each attached to the housing and the housing is attached to a location in the vehicle conducive to measuring pressure and acceleration signals corresponding to an impact event. The sensor assembly is configured to provide two independent signals (one for pressure and one for acceleration) to a control unit. The control unit compares both signals to confirm occurrence of the impact event in order to deploy automatic safety devices to protect vehicle occupants while avoiding inadvertent deployment of the safety devices.

Abstract: There is disclosed an assay to determine the effect of an applied agent or influence or other stimulus on the sub-cellular localisation of the expressed product of a nucleotide sequence (“the nucleotide sequence under investigation”), comprising: (i) transfecting a cell population with a cloned expression vector comprising a composite nucleotide sequence encoding the nucleotide sequence under investigation and a detectable tag, arranged such that the product of the expressed composite nucleotide sequence includes the expressed detectable tag; (ii) applying the applied agent, influence or other stimulus to at least a portion of the transfected cell population; (iii) observing the sub-cellular location of the detectable tag in the transfected cell population and comparing the observed sub-cellular localisation to the sub-cellular localisation of the detectable tag in the cell population in the absence of said applied agent or influence.