Patents by Inventor Jeremy TOUATI

Jeremy TOUATI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230043948
    Abstract: The present invention is related to a method to be performed with one tissue type, wherein a specific combination of hydrogel features has been pre-selected for the said one tissue type to be tested. The present invention is also related to a kit of parts to perform said method.
    Type: Application
    Filed: December 1, 2020
    Publication date: February 9, 2023
    Applicant: PRECISION CANCER TECHNOLOGIES INC .
    Inventors: Simone RIZZI, Jeremy TOUATI, Giulia FREGNI, Cara BUCHANAN PISANO, Franck COUMAILLEAU, Emanuele GAUDIELLO, Sophie GRETTAZ, Nicolas CHARTIER, Mathieu HEULOT
  • Publication number: 20220296784
    Abstract: The present invention is related to a biofunctional three-dimensional hydrogel suitable for the expansion of freshly isolated or frozen intestinal cells and the formation of intestinal organoids therefrom, that avoids the use of a naturally-derived matrix such as Matrigel and provides intestinal organoids suitable for clinical applications and generated in a commercially feasible manner. The present invention is also related to a kit of parts comprising said hydrogel in combination with a suitable culture medium, and to a method of making organoids and expanding cells from freshly isolated or frozen intestinal cells with said kit of parts.
    Type: Application
    Filed: August 24, 2020
    Publication date: September 22, 2022
    Applicant: PRECISION CANCER TECHNOLOGIES INC.
    Inventors: Simone RIZZI, Jeremy TOUATI, Giulia FREGNI, Cara BUCHANAN PISANO, Franck COUMAILLEAU, Mathieu HEULOT
  • Patent number: 10760068
    Abstract: A hydrogel precursor formulation which is in the form of an unreacted powder. The formulation comprises an activating enzyme, preferably thrombin, a cross-linking enzyme, preferably a transglutaminase, and more preferably factor XIII transglutaminase. The cross-linking enzyme is activatable by the activating enzyme in water with or without a buffer, and at least one structural compound A. The structural compound is crosslinkable by a selective reaction mediated by the crosslinking enzyme to form a hydrogel, wherein the cross-linking enzyme is activated.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: September 1, 2020
    Assignee: QGEL SA
    Inventors: Simone Rizzi, Jeremy Touati
  • Publication number: 20190153420
    Abstract: A hydrogel precursor formulation which is in the form of an unreacted powder. The formulation comprises an activating enzyme, preferably thrombin, a cross-linking enzyme, preferably a transglutaminase, and more preferably factor XIII transglutaminase. The cross-linking enzyme is activatable by the activating enzyme in water with or without a buffer, and at least one structural compound A. The structural compound is crosslinkable by a selective reaction mediated by the crosslinking enzyme to form a hydrogel, wherein the cross-linking enzyme is activated.
    Type: Application
    Filed: July 20, 2017
    Publication date: May 23, 2019
    Inventors: Simone RIZZI, Jeremy TOUATI