Abstract: Described is a natural product-containing supplement that enhances intracellular concentration of bioactive molecules through inhibition of MDR efflux pumps. Specifically described are dosage forms for administration to a subject, the dosage forms having at least four ingredients selected from the group consisting of apigenin, cannabidiol, chrysin, harmine, caffeic acid, piperine, nobiletin, Hypericum perforatum extract, bee propolis, oleanolic acid, biochanin, luteolin, vanillin, honokiol, pterostilbene, and withaferin A. Upon administration to a mammalian subject, the dosage forms generally inhibit mis-regulated MDR efflux pumps that are responsible for pushing out good nutrients from the cell—thus increasing intracellular concentration of health-promoting compounds.

Abstract: Described, among other things, are dosage form for administration to a subject, the dosage forms having at least four ingredients selected from okra, quercetin, gypenosides from Gynostemma pentaphyllum, punicalagins from pomegranate, zinc gluconate, chromium picolinate, curcuminoids, cinnamon Ceylon, mangiferin, Gymnema sylvestre extract, Schisandra chinensis, bitter melon, and Costus igneus. Upon administration to a mammalian subject, the dosage forms generally promote the subject's health through the maintenance of a healthy blood sugar level.