Patents by Inventor Jeroen Mathijn Wissink
Jeroen Mathijn Wissink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11918732Abstract: A method for manufacturing an spray device includes assembling at least one spray nozzle plate into a thermoplastic holder, while controlling the temperature of the spray nozzle plate and/or the holder and as a result at least locally plastically deforming the holder permanently. After the thermoplastic deformation of a seat of the holder, a diameter of the seat of the holder upstream of the spray nozzle plate exceeds a diameter of the seat of the holder downstream of the nozzle plate. The thermoplastic holder may have a tapered seat, where the smallest cross section of the tapered seat is smaller than the spray nozzle plate, where a widest side of the tapered seat is pointing towards a supply side of the liquid.Type: GrantFiled: January 7, 2020Date of Patent: March 5, 2024Assignee: MEDSPRAY B.V.Inventors: Henri Van Egmond, Wilhelmus Petrus Johannes De Kruijf, Wietze Nijdam, Jeroen Mathijn Wissink, Cornelis Johannes Maria Van Rijn
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Publication number: 20200215276Abstract: A method for manufacturing an spray device includes assembling at least one spray nozzle plate into a thermoplastic holder, while controlling the temperature of the spray nozzle plate and/or the holder and as a result at least locally plastically deforming the holder permanently. After the thermoplastic deformation of a seat of the holder, a diameter of the seat of the holder upstream of the spray nozzle plate exceeds a diameter of the seat of the holder downstream of the nozzle plate. The thermoplastic holder may have a tapered seat, where the smallest cross section of the tapered seat is smaller than the spray nozzle plate, where a widest side of the tapered seat is pointing towards a supply side of the liquid.Type: ApplicationFiled: January 7, 2020Publication date: July 9, 2020Applicant: MEDSPRAY B.V.Inventors: Henri Van Egmond, Wilhelmus Petrus Johannes De Kruijf, Wietze Nijdam, Jeroen Mathijn Wissink, Cornelis Johannes Maria Van Rijn
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Patent number: 10632265Abstract: A method for manufacturing an spray device includes assembling at least one spray nozzle plate into a thermoplastic holder, while controlling the temperature of the spray nozzle plate and/or the holder and as a result at least locally plastically deforming the holder permanently. After the thermoplastic deformation of a seat of the holder, a diameter of the seat of the holder upstream of the spray nozzle plate exceeds a diameter of the seat of the holder downstream of the nozzle plate. The thermoplastic holder may have a tapered seat, where the smallest cross section of the tapered seat is smaller than the spray nozzle plate, where a widest side of the tapered seat is pointing towards a supply side of the liquid.Type: GrantFiled: June 19, 2015Date of Patent: April 28, 2020Assignee: Medspray B.V.Inventors: Henri Van Egmond, Wilhelmus Petrus Johannes De Kruijf, Wietze Nijdam, Jeroen Mathijn Wissink, Cornelis Johannes Maria Van Rijn
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Patent number: 10369300Abstract: An aerosol generator for generating an inhalation aerosol from an inhalation liquid, includes an intake duct for guiding air to a mouth of a user, and a nozzle, arranged in the intake duct for injecting the inhalation liquid into the intake duct. The nozzle is arranged for generating a Rayleigh droplet train of the inhalation liquid propagating along a droplet train propagation path. The intake duct includes at least two first orifices having at least partly opposing discharging directions extending towards the droplet train propagation path. The at least two first orifices are configured for providing respective first air streams in at least partly opposing directions so as to interact in the droplet train propagation path.Type: GrantFiled: March 7, 2014Date of Patent: August 6, 2019Assignee: MEDSPRAY XMEMS B.V.Inventors: Wilhelmus Petrus Johannes De Kruijf, Wietze Nijdam, Jeroen Mathijn Wissink, Tom Vincent Huijgen
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Patent number: 9802013Abstract: An inhaler with a mixing channel (1) for producing an aerosol to be inhaled includes an outlet (9) at one end that can be inserted in the mouth of a person in order to inhale the aerosol that is produced; at least one inlet (3) at its other end for drawing air into the mixing channel (1); and at least one injection zone (6) that lies between the inlet (3) and the outlet (9) and forms part of the channel wall. The injection zone (6) has at least one nozzle orifice (10) for supplying a liquid, especially a liquid drug, wherein the inner surface of the injection zone (6) is largely flush at least with that portion of the mean surface curvature (22) of the inner surface of the channel wall (11) that is adjacent to it on the inlet end. A possible height difference (17) between the inner surface of the injection zone (6) and that portion of the mean surface curvature (22) of the inner surface of the channel wall (11) that is adjacent to it is less than 1 mm or at most 100 ?m or at most 20 ?m.Type: GrantFiled: March 9, 2006Date of Patent: October 31, 2017Assignee: MEDSPRAY XMEMS BVInventors: Jeroen Mathijn Wissink, Wietze Nijdam, Iwan Rutger Heskamp, Marc Herman Padberg
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Publication number: 20170281880Abstract: A method for manufacturing an spray device includes assembling at least one spray nozzle plate into a thermoplastic holder, while controlling the temperature of the spray nozzle plate and/or the holder and as a result at least locally plastically deforming the holder permanently. After the thermoplastic deformation of a seat of the holder, a diameter of the seat of the holder upstream of the spray nozzle plate exceeds a diameter of the seat of the holder downstream of the nozzle plate. The thermoplastic holder may have a tapered seat, where the smallest cross section of the tapered seat is smaller than the spray nozzle plate, where a widest side of the tapered seat is pointing towards a supply side of the liquid.Type: ApplicationFiled: June 19, 2015Publication date: October 5, 2017Inventors: Henri Van Egmond, Wilhelmus Petrus Johannes De Kruijf, Wietze Nijdam, Jeroen Mathijn Wissink, Cornelis Johannes Maria Van Rijn
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Patent number: 9597490Abstract: The present invention provides a microneedle, comprising a shaft of a monocrystalline material having at least three walls which are formed by a crystal plane of the monocrystalline material; and a tip connected to an end of the shaft comprising at least three walls which are formed by a crystal plane of the material. The material is preferably silicon. Two of the walls of the tip are formed by the same crystal planes as two walls of the shaft. These two walls are formed by a <111> crystal plane. Preferably, three walls of the tip are formed by a <111> crystal plane.Type: GrantFiled: June 24, 2009Date of Patent: March 21, 2017Assignee: U-NEEDLE HOLDING B.V.Inventors: Johan Willem Berenschot, Jeroen Mathijn Wissink, Niels Roelof Tas, Meint Jelle DeBoer
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Patent number: 9566398Abstract: A method of manufacturing an atomizing body for an atomizing device includes the steps of providing a support element having a first layer on a first surface of the support element and a second layer on a second surface of the support element, the first layer including a first perforated membrane and the second layer including a process orifice, etching a cavity through the support element, the cavity forming a fluid connection from the process orifice to the perforated membrane, by providing etching substance to the process orifice. The atomizing body as obtained may advantageously be applied in an atomizing device or an inhaler.Type: GrantFiled: April 22, 2010Date of Patent: February 14, 2017Assignee: MEDSPRAY XMEMS B.V.Inventors: Iwan Rutger Heskamp, Wilhelmus Petrus Johannes de Kruijf, Wietze Nijdam, Jeroen Mathijn Wissink
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Publication number: 20160015912Abstract: An aerosol generator for generating an inhalation aerosol from an inhalation liquid, includes an intake duct for guiding air to a mouth of a user, and a nozzle, arranged in the intake duct for injecting the inhalation liquid into the intake duct. The nozzle is arranged for generating a Rayleigh droplet train of the inhalation liquid propagating along a droplet train propagation path. The intake duct includes at least two first orifices having at least partly opposing discharging directions extending towards the droplet train propagation path. The at least two first orifices are configured for providing respective first air streams in at least partly opposing directions so as to interact in the droplet train propagation path.Type: ApplicationFiled: March 7, 2014Publication date: January 21, 2016Inventors: Wilhelmus Petrus Johannes DE KRUIJF, Wietze NIJDAM, Jeroen Mathijn WISSINK, Tom Vincent HUIJGEN
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Patent number: 8936160Abstract: Nozzle device and nozzle for atomisation and/or filtration as well as methods for using the same. The present invention relates to a nozzle and nozzle device for atomisation, in particular a micro-machined reinforced nozzle plate, that may produce small liquid droplets in air (spray) or into a liquid (emulsion) with a narrow droplet size distribution and to make small air bubbles into a liquid (foam) and to methods of making the same. The invention is further related to a nozzle part for filtration as well as means and methods to facilitate atomisation and filtration.Type: GrantFiled: April 16, 2012Date of Patent: January 20, 2015Assignee: Aquamarijn Holding B.V.Inventors: Cornelis Johannes Maria Van Rijn, Jeroen Mathijn Wissink, Wietze Nijdam
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Patent number: 8814059Abstract: An atomizing device, includes an atomizing body (1) with an inlet (16) for receiving a fluid under increased pressure, and with at least one set of outflow ports (18) for allowing the fluid to escape on a delivery side with forming of a vapor. Imaginary central axes of the outflow ports directed in a flow direction herein enclose a mutual angle (?) in order to intersect each other at an intersection (S). The atomizing body includes a roof (21) and a bottom (11 which extend over at least a first distance (d1) beyond the set of outflow ports (18) and bound a vaporizing space (17) on either side. The intersection (S) of the imaginary central axes of the outflow ports lies at a second distance (d2) from the set of outflow ports, wherein the second distance (d2) is greater than the first distance (d1) and extends beyond the vaporizing space.Type: GrantFiled: June 30, 2008Date of Patent: August 26, 2014Assignee: Medspray XMEMS B.V.Inventors: Jeroen Mathijn Wissink, Iwan Rutger Heskamp, Wilhelmus Petrus Johannes De Kruijf, Wietze Nijdam, Cornelis Johannes Maria Van Rijn
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Publication number: 20120228238Abstract: Nozzle device and nozzle for atomisation and/or filtration as well as methods for using the same. The present invention relates to a nozzle and nozzle device for atomisation, in particular a micro-machined reinforced nozzle plate, that may produce small liquid droplets in air (spray) or into a liquid (emulsion) with a narrow droplet size distribution and to make small air bubbles into a liquid (foam) and to methods of making the same. The invention is further related to a nozzle part for filtration as well as means and methods to facilitate atomisation and filtration.Type: ApplicationFiled: April 16, 2012Publication date: September 13, 2012Applicant: MEDSPRAY XMEMS B.V.Inventors: Cornelis Johannes Maria VAN RIJN, Jeroen Mathijn Wissink, Wietze Nijdam
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Publication number: 20120012105Abstract: A method of manufacturing an atomising body for an atomising device includes the steps of providing a support element having a first layer on a first surface of the support element and a second layer on a second surface of the support element, the first layer including a first perforated membrane and the second layer comprising a process orifice, etching a cavity through the support element, the cavity forming a fluid connection from the process orifice to the perforated membrane, by providing etching substance to the process orifice. The atomising body as obtained may advantageously be applied in an atomising device or an inhaler.Type: ApplicationFiled: April 22, 2010Publication date: January 19, 2012Applicant: MEDSPRAY XMEMS B.V.Inventors: Iwan Rutger Heskamp, Wilhelmus Petrus Johannes de Kruijf, Wietze Nijdam, Jeroen Mathijn Wissink
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Publication number: 20110172605Abstract: The present invention provides a microneedle, comprising a shaft of a monocrystalline material having at least three was which are formed by a crystal plane of the monocrystalline material; and a tip connected to an end of the shaft comprising at least three walls which are formed by a crystal plane of the material. The material is preferably silicon. Two of the walls of the tip are formed by the same crystal planes as two walls of the shaft. These two walls are formed by a <111> crystal plane. Preferably, three walls of the tip are formed by a <111> crystal plane.Type: ApplicationFiled: June 24, 2009Publication date: July 14, 2011Applicant: U-NEEDLE HOLDING B.V.Inventors: Johan Willem Berenschot, Jeroen Mathijn Wissink, Niels Roelof Tas, Meint Jelle DeBoer
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Patent number: 7963466Abstract: Nozzle device and nozzle for atomization and/or filtration as well as methods for using the same. The nozzle and nozzle device for atomization, in particular a micro-machined reinforced nozzle plate, may produce small liquid droplets in air (spray) or into a liquid (emulsion) with a narrow droplet size distribution and make small air bubbles into a liquid (foam). A nozzle part for filtration as well as elements and methods to facilitate atomization and filtration are also disclosed.Type: GrantFiled: April 8, 2005Date of Patent: June 21, 2011Assignee: Medspray XEMEMS B.V.Inventors: Cornelis Johannes Maria Van Rijn, Jeroen Mathijn Wissink, Wietze Nijdam
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Publication number: 20110049262Abstract: An atomizing device, includes an atomizing body (1) with an inlet (16) for receiving a fluid under increased pressure, and with at least one set of outflow ports (18) for allowing the fluid to escape on a delivery side with forming of a vapour. Imaginary central axes of the outflow ports directed in a flow direction herein enclose a mutual angle (?) in order to intersect each other at an intersection (S). The atomizing body includes a roof (21) and a bottom (11 which extend over at least a first distance (d1) beyond the set of outflow ports (18) and bound a vaporizing space (17) on either side. The intersection (S) of the imaginary central axes of the outflow ports lies at a second distance (d2) from the set of outflow ports, wherein the second distance (d2) is greater than the first distance (d1) and extends beyond the vaporizing space.Type: ApplicationFiled: June 30, 2008Publication date: March 3, 2011Applicant: MEDSPRAY XMEMS B.V.Inventors: Jeroen Mathijn Wissink, Iwan Rutger Heskamp, Wilhelmus Petrus Johannes De Kruijf, Wietze Nijdam, Cornelis Johannes Maria Van Rijn
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Publication number: 20100288271Abstract: The invention relates to a system for artificial respiration of persons, comprising: a respirator apparatus, comprising: a respirator device and at least one respiratory tube coupled to the respirator device, which respiratory tube is adapted to enable respiration of a person; and at least one atomizing device for atomizing an additive in an airflow to be inhaled by the persons, comprising: at least one atomized body coupled to the respiratory tube and at least one supply container for holding a supply of at least one additive.Type: ApplicationFiled: November 9, 2007Publication date: November 18, 2010Applicant: INDES HOLDING B.V.Inventors: Wilhelmus Petrus Johannes De Kruijf, Klaas Jacobus Blacquiere, Evert Jan Klip, Jeroen Mathijn Wissink, Marco Voogsgerd
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Publication number: 20090050137Abstract: An inhaler with a mixing channel (1) for producing an aerosol to be inhaled includes an outlet (9) at one end that can be inserted in the mouth of a person in order to inhale the aerosol that is produced; at least one inlet (3) at its other end for drawing air into the mixing channel (1); and at least one injection zone (6) that lies between the inlet (3) and the outlet (9) and forms part of the channel wall. The injection zone (6) has at least one nozzle orifice (10) for supplying a liquid, especially a liquid drug, wherein the inner surface of the injection zone (6) is largely flush at least with that portion of the mean surface curvature (22) of the inner surface of the channel wall (11) that is adjacent to it on the inlet end. A possible height difference (17) between the inner surface of the injection zone (6) and that portion of the mean surface curvature (22) of the inner surface of the channel wall (11) that is adjacent to it is less than 1 mm or at most 100 ?m or at most 20 ?m.Type: ApplicationFiled: March 9, 2006Publication date: February 26, 2009Inventors: Jeroen Mathijn Wissink, Wietze Nijdam, Iwan Rutger Heskamp, Marc Herman Padberg